Abstract: The current invention provides methods which can be implemented alongside clinical variables as risk prediction tools for improved prediction of CKD progression and mortality. Surprisingly it was found that decreased C3a-desArg was associated with adverse outcome in CKD, and when combined with increased STNFR1 and NGAL it gave an excellent predictor of progression to a composite endpoint in CKD patients.

Abstract: Systems and methods for delivering and implanting heart valves are disclosed. The delivery systems can include an integrated introducer. The integrated introducer can include a sheath having an inner diameter that is smaller than the outer diameter of a delivery capsule of the delivery system and an outer diameter that is approximately equal to the outer diameter of the delivery capsule. The integrated introducer can include a hub having a hemostatic seal. The hub can have a locking mechanism configured to fix the integrated introducer in place on the delivery system.

Abstract: Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity and treating diseases mediated by GPR120 by administering such compounds and compositions.

Abstract: One or more Bluetooth® low energy (BLE) beacons in communication with a remote server that provides check in capabilities and payment capabilities may be installed at a location. The BLE beacons may connect with a user's mobile device when the user enters the location and allow the user to check in to the location and authorize payments to be made at the location. Once the user is checked in to the location, the user may be provided with additional functionality, benefits, offers, and applications related to the location and facilitated by the check in. Further, the user may be pre-checked in into a next location when the user is at a current location.

Abstract: Techniques are described for determining a value metric for each of a plurality of payment cards, and recommending payment card(s) based on their respective value metrics. Implementations provide a recommendation engine that analyzes user data and card data, and recommends payment card(s) that may be suitable for a user. The engine consumes usage data and credit score and uses that information, along with characteristics of various available cards, to develop a value metric for each payment card that indicates how valuable owning the card would be to the particular user, such as how much money the user can expect to make or lose every year if they use the card as indicated, given the card's interest rate, rewards, fees, and so forth. The engine can rank the cards according to their value metrics, and the top-ranked card(s) are presented to the user as recommendations in a user interface.

Abstract: An internal combustion engine includes a plurality of cylinders, and a plurality of fuel injectors configured to inject a fuel into a respective cylinder of the plurality cylinders. The fuel injectors are received within a bore in a body of the engine and when in service are movable in relation to the body. A seal surrounds each fuel injector and extends between each injector and a peripheral region of the bore.

Abstract: A method of forming a fin configured for use with a water sports board. The method includes providing a mold having a mold cavity and a first insert pre-preg sheet each including structural strands bonded by a first resin material. The method further includes placing the first insert pre-preg sheet within the mold cavity. The method further includes injecting a third resin material under pressure into the mold cavity. The method further includes injecting a core substance only in the form of a gaseous material into the third resin material to form a unitary hollow volume within the third resin material.

Abstract: An intake assembly for an internal combustion engine, includes an intake manifold including a first plenum and a plurality of intake runners, the first plenum including an air supply inlet, the intake runners configured to be couplable to a cylinder head of the engine for supplying an air-fuel mixture thereto, the intake manifold configured such that, in use, air is supplied from the air supply inlet to the intake runners via the first plenum; a plurality of fuel injectors, each arranged to inject a fuel into one of the intake runners; and a fuel rail coupled to the plurality of fuel injectors, the fuel rail including a fuel supply inlet, and configured to supply fuel from the fuel supply inlet to the plurality of fuel injectors, in use. The fuel rail is mounted to the first plenum.

Abstract: A method of in-line automated inspection of a mechanical part comprising receiving a mechanical part datum, orienting the mechanical part datum within a representative inspection system, and examining each face of the plurality of faces of the mechanical part datum, wherein examining each face of the plurality of faces of the mechanical part datum comprises dividing the face into regions as a function of stylus tip data. The method comprises generating a fixture adapter model for the mechanical part datum as a function of a local region of the mechanical part datum, generating a measurement of at least a pair of part geometric data, wherein generating a measurement comprises selecting the at least a pair of part geometric data as a function of the at least an alignment datum and displaying the measurement of at least the pair of part geometric data. The method comprises producing the fixture adapter.

Abstract: A method of forming a fin configured for use with a water sports board. The method includes providing a mold having a mold cavity and first and second insert pre-preg sheets each including structural strands respectively bonded by first and second resin materials. The method further includes placing the insert pre-preg sheets within the mold cavity. The method further includes injecting a third resin material under pressure into the mold cavity between the first insert pre-preg sheet and the second insert pre-preg sheet to urge the first insert pre-preg sheet and the second insert pre-preg sheet away from each other and towards respective ones of the pair of mold cavity faces, and dispose the third resin material between the first insert pre-preg sheet and the second insert pre-preg sheet to space at least a portion of the first insert pre-preg sheet from the second insert pre-preg sheet.

Abstract: Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity and treating diseases mediated by GPR120 by administering such compounds and compositions.

Abstract: Technologies for power-aware scheduling include a computing device that receives network packets. The computing device classifies the network packets by priority level and then assigns each network packet to a performance group bin. The packets are assigned based on priority level and other performance criteria. The computing device schedules the network packets assigned to each performance group for processing by a processing engine such as a processor core. Network packets assigned to performance groups having a high priority level are scheduled for processing by processing engines with a high performance level. The computing device may select performance levels for processing engines based on processing workload of the network packets. The computing device may control the performance level of the processing engines, for example by controlling the frequency of processor cores. The processing workload may include packet encryption. Other embodiments are described and claimed.

Abstract: A beanbag comprising a first layer, forming a generally closed container, a layer of cushioning lining an inside of the first layer, a cavity within the closed container, and a resealable access port to access the cavity. In a preferred embodiment, the first layer is marine vinyl, the cushioning is a uniform layer of marine foam, and the resealable access port is a marine-grade zipper. In another embodiment, the cushioning is a layer of beanbag beans. In another embodiment, the resealable access port is an opening at the end of a protrusion, wherein the protrusion can be rolled-up and secured with a fastening mechanism. The beanbag is intended for, but not limited to, use outdoors, such as on the beach, the decks of boats, patios, pool sides, and in water. In a preferred embodiment, the beanbag floats on water and further comprises a reflective band and reflective elements.

Abstract: A beanbag comprising a first layer, forming a generally closed container, a layer of cushioning lining an inside of the first layer, a cavity within the closed container, and a resealable access port to access the cavity. In a preferred embodiment, the first layer is marine vinyl, the cushioning is a uniform layer of marine foam, and the resealable access port is a marine-grade zipper. In another embodiment, the cushioning is a layer of beanbag beans. In another embodiment, the resealable access port is an opening at the end of a protrusion, wherein the protrusion can be rolled-up and secured with a fastening mechanism. The beanbag is intended for, but not limited to, use outdoors, such as on the beach, the decks of boats, patios, pool sides, and in water. In a preferred embodiment, the beanbag floats on water and further comprises a reflective band and reflective elements.

Abstract: Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity and treating diseases mediated by GPR120 by administering such compounds and compositions.

Abstract: A hand tool may include a head section defining a first grip portion, a handle section and a second grip portion. The head section includes a top jaw and a bottom jaw defining the first grip portion. The handle section includes a top handle and a bottom handle. The top jaw and the bottom handle forming a first unitary piece, and the bottom jaw and the top handle forming a second unitary piece. The first and second unitary pieces are joined at a pivot point. The second grip portion includes a top grip portion provided at the top handle and a bottom grip portion provided at the bottom handle. The top and bottom grip portions substantially face each other. The first grip portion is made of a metallic material and the second grip portion is made of a non-metallic material.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: A method of in-line automated inspection of a mechanical part comprising receiving a mechanical part datum, orienting the mechanical part datum within a representative inspection system, and examining each face of the plurality of faces of the mechanical part datum, wherein examining each face of the plurality of faces of the mechanical part datum comprises dividing the face into regions as a function of stylus tip data. The method comprises generating a fixture adapter model for the mechanical part datum as a function of a local region of the mechanical part datum, generating a measurement of at least a pair of part geometric data, wherein generating a measurement comprises selecting the at least a pair of part geometric data as a function of the at least an alignment datum and displaying the measurement of at least the pair of part geometric data. The method comprises producing the fixture adapter.

Abstract: Provided herein are compounds, compositions including them, and methods of modulating GPR120 activity and treating diseases mediated by GPR120 by administering such compounds and compositions.