Patents by Inventor John Alston Kellum

John Alston Kellum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11629370
    Abstract: A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: April 18, 2023
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Duquesne University of the Holy Spirit
    Inventors: John Alston Kellum, John D. Hempel, Robert Hugh Edgar, John Andrew Viator
  • Publication number: 20210262001
    Abstract: A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
    Type: Application
    Filed: March 16, 2021
    Publication date: August 26, 2021
    Inventors: JOHN ALSTON KELLUM, JOHN D. HEMPEL, ROBERT HUGH EDGAR, JOHN ANDREW VIATOR
  • Patent number: 10961557
    Abstract: A system for identifying at least one species, strain or type of bacteria in a sample including at least one a labeled bacteriophage which binds selectively to the species, strain or type of bacteria, the at least one labeled bacteriophage comprising a label attached thereto, the system further comprising a detection system adapted to detect the labeled bacteriophage bound to the species of bacteria.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: March 30, 2021
    Assignees: University of Pittsburgh Of the Commonwealth System of Higher Education, Duquesne University of the Holy Spirit
    Inventors: John Alston Kellum, John D. Hempel, Robert Hugh Edgar, John Andrew Viator
  • Publication number: 20200123587
    Abstract: A system for identifying at least one species, strain or type of bacteria in a sample including at least one a labeled bacteriophage which binds selectively to the species, strain or type of bacteria, the at least one labeled bacteriophage comprising a label attached thereto, the system further comprising a detection system adapted to detect the labeled bacteriophage bound to the species of bacteria.
    Type: Application
    Filed: December 19, 2019
    Publication date: April 23, 2020
    Inventors: JOHN ALSTON KELLUM, JOHN D. HEMPEL, ROBERT HUGH EDGAR, JOHN ANDREW VIATOR
  • Patent number: 10544443
    Abstract: A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: January 28, 2020
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Duquesne University of the Holy Spirit
    Inventors: John Alston Kellum, John D. Hempel, Robert Hugh Edgar, John Andrew Viator
  • Patent number: 10322221
    Abstract: A method of reducing the concentration of carbon dioxide in blood plasma includes removing blood from a patient and treating or processing at least blood plasma of the blood by flowing the blood plasma on one side of at least one semi-permeable membrane and flowing a dialysate on the other side of the at least one semi-permeable membrane. The dialysate has a concentration of bicarbonate less than the concentration of bicarbonate in the blood plasma before treating the blood plasma and has a composition such that the blood plasma strong ion difference that results from treating the blood plasma in conjunction with an achieved reduction in blood plasma CO2 concentration results in a blood plasma pH that does not change by more than +/?0.5 during treatment.
    Type: Grant
    Filed: January 18, 2014
    Date of Patent: June 18, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: John Alston Kellum, Jr., Matthew Cove, William J. Federspiel
  • Patent number: 10258734
    Abstract: A method of modifying cells includes removing fluid including cells from a patient, contacting the removed fluid from the patient with at least one surface upon which at least one agent to interact at least one cell receptor is immobilized to modify cells in the fluid, and returning the fluid to the patient. The agent can, for example, be immobilized via covalent bonding or ionic bonding to the at least one surface. The fluid can, for example, be blood or a blood fraction. The agent can, for example, be an agonist, an antagonist or an inverse agonist.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: April 16, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: William J. Federspiel, John Alston Kellum, Kai Singbartl
  • Publication number: 20180216154
    Abstract: A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
    Type: Application
    Filed: July 29, 2016
    Publication date: August 2, 2018
    Inventors: JOHN ALSTON KELLUM, JOHN D. HEMPEL, ROBERT HUGH EDGAR, JOHN ANDREW VIATOR
  • Publication number: 20170173254
    Abstract: A method of modifying cells includes removing fluid including cells from a patient, contacting the removed fluid from the patient with at least one surface upon which at least one agent to interact at least one cell receptor is immobilized to modify cells in the fluid, and returning the fluid to the patient. The agent can, for example, be immobilized via covalent bonding or ionic bonding to the at least one surface. The fluid can, for example, be blood or a blood fraction. The agent can, for example, be an agonist, an antagonist or an inverse agonist.
    Type: Application
    Filed: March 8, 2017
    Publication date: June 22, 2017
    Inventors: WILLIAM J. FEDERSPIEL, JOHN ALSTON KELLUM, KAI SINGBARTL
  • Publication number: 20150335807
    Abstract: A method of reducing the concentration of carbon dioxide in blood plasma includes removing blood from a patient and treating or processing at least blood plasma of the blood by flowing the blood plasma on one side of at least one semi-permeable membrane and flowing a dialysate on the other side of the at least one semi-permeable membrane. The dialysate has a concentration of bicarbonate less than the concentration of bicarbonate in the blood plasma before treating the blood plasma and has a composition such that the blood plasma strong ion difference that results from treating the blood plasma in conjunction with an achieved reduction in blood plasma CO2 concentration results in a blood plasma pH that does not change by more than +/?0.5 during treatment.
    Type: Application
    Filed: January 18, 2014
    Publication date: November 26, 2015
    Inventors: John Alston Kellum, JR., Matthew Cove, William J. Federspiel
  • Publication number: 20120201799
    Abstract: A method of modifying cells includes removing fluid including cells from a patient, contacting the removed fluid from the patient with at least one surface upon which at least one agent to interact at least one cell receptor is immobilized to modify cells in the fluid, and returning the fluid to the patient. The agent can, for example, be immobilized via covalent bonding or ionic bonding to the at least one surface. The fluid can, for example, be blood or a blood fraction. The agent can, for example, be an agonist, an antagonist or an inverse agonist.
    Type: Application
    Filed: October 7, 2010
    Publication date: August 9, 2012
    Inventors: William J. Federspiel, John Alston Kellum, Kai Singbartl