Abstract: The anastomosis trimming device is used for trimming one end section of a tubular structure, such as a blood vessel or vascular graft, which is to be anastomosed, to provide the anastomotic end with a smooth, reproducible shape. The end is trimmed in such a manner as to mate with a similarly trimmed end of a second tubular structure or with an incision in the side of a second tubular structure. The device comprises first and second arms pivotably connected to each other at one end, with the first arm mounting a cutting die including a cutting element on a free end thereof. The cutting element faces toward the second arm, and the free end of the second arm mounts a mating element facing toward the first arm which, upon pivoting of the free ends of the first and second arm, mates with the cutting element on the first arm.

Abstract: Composite grafts are provided that have a porous wall structure to permit ingrowth thereinto under in vivo conditions but which include a generally non-porous membrane in the wall to prevent substantial fluid passage therethrough so as to provide an implantable porous graft that does not require preclotting prior to implantation. One or more of such membranes are formed in place by applying a polymeric membrane-forming composition during the formation of a graft body by winding elongated extruded fibers on a mandrel.

Abstract: Vascular grafts are provided that have an external surface which has a porous structure that is conducive to tissue ingrowth thereinto after the vascular graft has been implanted. The vascular graft is prepared by winding an extruded fiber onto a mandrel in the presence of intermittently applied electrostatic forces. Such vascular graft may include an internal surface that was formed under the influence of the electrostatic charge, which internal surface has a porosity that is substantially less than that of said porous external surface.