Abstract: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a ?-galactoside, an ?- or ?-N-acetylglucosamine, or a sialic acid moiety.

Abstract: In the present invention, a dripless syringe is provided that includes a barrel having fluid therein, the barrel defining an open end and a nozzle opposite the open end, a plunger disposed at least partially within the open end and including a body and a push pin extending from one end of the body, a seal plate slidably mounted to the push pin and a bung disposed over the seal plate and the push pin and sealingly engaged between the seal plate and the barrel the seal plate enables the bung to remain in sealing engagement with the interior of the barrel while the plunger is moved within the barrel. Further, when pressure is removed to cease dispensing of the fluid, the pin allows the bung to retract and provide a negative pressure on the fluid to prevent drips of fluid from leaking out of the nozzle.

Abstract: A device for delivering fluid includes a housing having a proximal end configured to receive a fluid source and a distal end configured to receive a treatment tip. In its interior, the housing includes at least a first fluid line in fluid communication with the fluid source and with the treatment tip, at least a first pump in-line with the first fluid line and configured to urge fluid from the fluid source to the treatment tip, control circuitry in electrical communication with the pump, and a power source configured to supply continuous output power to deliver the fluid to the treatment tip, the power source being in electrical communication with the control circuitry. The housing further is provided with user-operable controls and operation monitors.

Abstract: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a ?-galactoside, an ?- or ?-N-acetylglucosamine, or a sialic acid moiety.

Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: A bypass device and kit for delivering a fluid to a dental area for use with a dental handpiece. The device comprises a fluid reservoir, a length of hollow tubing that will be attached externally to the handpiece, and a nosepiece connected to the tubing. Fluid is delivered to, the dental area through the nosepiece, independently of the dental handpiece.

Abstract: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a ?-galactoside, an ?- or ?-N-acetylglucosamine, or a sialic acid moiety.

Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based compound. The resultant agent is generally less caustic than previous agents, when using a similar amount of active material.

Abstract: An evacuation and/or irrigation device for use in connection with a vacuum source and used in a relatively localized surgical area. The evacuation device has a main body connected to a dental tool and a hook-like evacuation needle connected to the body. The needle has a plurality of spaced apart vacuum ports to provide irrigation circumferentially to sterilize and clean the surgical area.

Abstract: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a ?-galactoside, an ?- or ?-N-acetylglucosamine, or a sialic acid moiety.

Abstract: A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based compound. The resultant agent is generally less caustic than previous agents, when using a similar amount of active material.

Abstract: A bypass device and kit for delivering a fluid to a dental area for use with a dental handpiece. The device comprises a fluid reservoir, a length of hollow tubing that will be attached externally to the handpiece, and a nosepiece connected to the tubing. Fluid is delivered to the dental area through the nosepiece, independently of the dental handpiece.