Patents by Inventor John C. Clark

John C. Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030215507
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Application
    Filed: April 14, 2003
    Publication date: November 20, 2003
    Applicant: Wyeth
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Publication number: 20030204015
    Abstract: This invention provides compositions for treating fibrous substrates to render those substrates durably repellent to water and oil and durably resistant to dry soil comprising a 1) fluorochemical urethane formed by reacting a tri- or higher order isocyanate with a fluorochemical monofunctional compound and optionally a non-fluorinated aliphatic monofunctional compound; and 2) a fluorochemical polymeric surfactant
    Type: Application
    Filed: April 17, 2002
    Publication date: October 30, 2003
    Inventors: Malcolm B. Burleigh, David P. Cheatham, John C. Clark, A. Dale Otteson
  • Patent number: 6613862
    Abstract: A process is described which imparts exceptional antisoiling, anti-staining and repellent properties to carpets. The process makes use of a water-based exhaustion process wherein the water-based treating solution contains (1) glassy fluorochemical material, glassy hydrocarbon material, or combinations thereof; (2) a stainblocking material; (3) a polyvalent metal salt, acid, or combinations thereof; and (4) water. Subsequent to exhaustion, the wet treated carpet is heated, usually in a steaming step, rinsed, and dried in a dry heat oven.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: September 2, 2003
    Assignee: 3M Innovative Properties Company
    Inventors: John C. Clark, John C. Newland, Robert F. Kamrath, Malcolm B. Burleigh, Kevin R. Schaffer
  • Publication number: 20030136938
    Abstract: This invention provides compositions for treating fibrous substrates to render those substrates durably repellent to water and oil and durably resistant to dry soil comprising a fluorochemical urethane formed by reacting a tri- or higher order isocyanate with a fluorochemical monofunctional compound; and optionally a non-fluorinated aliphatic monofunctional compound.
    Type: Application
    Filed: December 4, 2001
    Publication date: July 24, 2003
    Applicant: 3M Innovative Properties Company
    Inventors: John C. Clark, Malcolm B. Burleigh, Chetan P. Jariwala, Qiu Zai-Ming
  • Publication number: 20030139521
    Abstract: A fluorochemical composition for rendering a fibrous substrate oil and/or water repellent which comprises a solution or dispersion of a fluoropolymer having a partially or fully fluorinated backbone and comprising one or more repeating units corresponding to the general formula: 1
    Type: Application
    Filed: May 21, 2001
    Publication date: July 24, 2003
    Inventors: Jeffrey G. Linert, E. Steven McAlister, Lian S. Tan, Richard S. Buckanin, Naiyong Jing, Frans A. Audenaert, Thomas J. Blong, John C. Clark, Linda G. Cote, Harald Kaspar, Franz Marz
  • Publication number: 20030026997
    Abstract: Fluorochemical urethane compositions comprising one or more compounds or oligomers having at least on fluorine-containing repeatable unit and at least one fluorine-containing terminal group are described. The compositions are useful as coatings or incorporated as melt additives. The fluorochemical compositions impart oil and water repellency to the substrate. In other aspects, this invention relates to processes for imparting oil and water repellency characteristics to substrates and articles.
    Type: Application
    Filed: March 9, 2001
    Publication date: February 6, 2003
    Inventors: Zai-Ming Qiu, John C. Clark, Wayne W. Fan
  • Publication number: 20020197307
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Application
    Filed: May 21, 2002
    Publication date: December 26, 2002
    Applicant: Wyeth
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Stephen A. White
  • Patent number: 6419958
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: July 16, 2002
    Assignee: Wyeth
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Patent number: 6403120
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and fiber provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Grant
    Filed: September 12, 2001
    Date of Patent: June 11, 2002
    Assignee: Wyeth
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Publication number: 20020025339
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and fiber provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Application
    Filed: September 12, 2001
    Publication date: February 28, 2002
    Applicant: American Home Products Corporation
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Publication number: 20010055612
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Application
    Filed: June 19, 2001
    Publication date: December 27, 2001
    Applicant: American Home Products Corporation Five Giralda Farms
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Patent number: 6274171
    Abstract: This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma levels than conventional tablet formulations which must be administered two or more times a day and further provides a lower incidence of nausea and vomiting than the conventional tablets. More particularly, the invention comprises an extended release formulation of venlafaxine hydrochloride comprising a therapeutically effective amount of venlafaxine hydrochloride in spheroids comprised of venlafaxine hydrochloride, microcrystalline cellulose and, optionally, hydroxypropylmethylcellulose coated with a mixture of ethyl cellulose and hydroxypropylmethylcellulose.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: August 14, 2001
    Assignee: American Home Products Corporation
    Inventors: Deborah M. Sherman, John C. Clark, John U. Lamer, Steven A. White
  • Publication number: 20010005530
    Abstract: A process is described which imparts exceptional antisoiling, anti-staining and repellent properties to carpets. The process makes use of a water-based exhaustion process wherein the water-based treating solution contains (1) glassy fluorochemical material, glassy hydrocarbon material, or combinations thereof; (2) a stainblocking material; (3) a polyvalent metal salt, acid, or combinations thereof; and (4) water. Subsequent to exhaustion, the wet treated carpet is heated, usually in a steaming step, rinsed, and dried in a dry heat oven.
    Type: Application
    Filed: February 1, 2001
    Publication date: June 28, 2001
    Applicant: 3M Innovative Properties Company
    Inventors: John C. Clark, John C. Newland, Robert F. Kamrath, Malcolm B. Burleigh, Kevin R. Schaffer
  • Patent number: 6198529
    Abstract: An automated inspection system particularly adapted for detection and discrimination of surface irregularities of specularly reflecting and other materials, such as are employed in laminate chip carriers and printed circuit boards, includes an area scan image sensor allowing illumination sources to surround an area of a surface being inspected. The illumination source preferably provides either or both bright field and dark field illumination of the surface; developing generally complementary images of surface irregularities. A self-registering rules-driven process for developing inspection masks reduces alignment operations and improves performance. Image enhancement and morphological operations to detect surface irregularities are performed by digital signal processing, preferably using a dedicated vision processor. Masks screen potential defects to critical mounting and bonding surfaces accurately without requiring alignment of data or reference images to acquired images.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: March 6, 2001
    Assignee: International Business Machines Corporation
    Inventors: John C. Clark, Jr., Earle W. Gillis, Christopher J. Majka, Matthew F. Seward, Michael M. Westgate
  • Patent number: 6197378
    Abstract: A process is described which imparts exceptional antisoiling, anti-staining and repellent properties to carpets. The process makes use of a water-based exhaustion process wherein the water-based treating solution contains (1) glassy fluorochemical material, glassy hydrocarbon material, or combinations thereof; (2) a stainblocking material; (3) a polyvalent metal salt, acid, or combinations thereof; and (4) water. Subsequent to exhaustion, the wet treated carpet is heated, usually in a steaming step, rinsed, and dried in a dry heat oven.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: March 6, 2001
    Assignee: 3M Innovative Properties Company
    Inventors: John C. Clark, John C. Newland, Robert F. Kamrath, Malcolm B. Burleigh, Kevin R. Schaffer
  • Patent number: 6052996
    Abstract: A heat recovery apparatus and method suitable for steam cycle electrical generating plants including at the exhaust of a steam turbine one or more heat transfer units for capturing the heat in steam, including the latent heat of vaporization of the steam. Heat is transferred from the steam to a working fluid in at least one heat transfer unit. The heat transfer unit may also include a cooling apparatus. Piping and valves establish communication of the working fluid between the heat transfer unit and the gas turbine generator. The working fluid is moved through the system by selectively isolating sections of the piping and adding or taking away heat from adjacent sections to create pressure differentials. Connecting adjacent sections results in the movement of the working fluid mass as a result of the pressure equalization.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: April 25, 2000
    Inventor: John C. Clark
  • Patent number: 5674592
    Abstract: Low energy surfaces based on nanostructured films exhibit advancing and receding contact angles for liquids such that (1) the difference between the advancing and receding contact angles approaches zero and (2) the advancing and receding contact angles approach 180.degree.. The low energy surface of the present invention comprises a nanostructured film coated with an organized molecular assembly (OMA). Advantageously, the chemical and wetting characteristics of the surface can be altered by changing the functionality of the OMA end groups exposed to the environment in contact with the surface of the nanostructured film.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: October 7, 1997
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: John C. Clark, Mark K. Debe, Harry E. Johnson, Danna L. Ross, Robert K. Schultz
  • Patent number: 5248306
    Abstract: A retainer is used in combination with two tubular flow connectors to prevent the inadvertent disconnection of I.V. tubing sets. The retainer includes at least one open collar having a flexible opening so as to be radially and securely attachable adjacent to an increased diameter portion on a tubing connector. A pair of parallel straps connects the collar with an axially pivotable joint so as to facilitates easy manipulation and engagement of the retainer.
    Type: Grant
    Filed: August 25, 1992
    Date of Patent: September 28, 1993
    Assignee: Abbott Laboratories
    Inventors: John C. Clark, William J. Hook, Mark E. Larkin
  • Patent number: 4659241
    Abstract: A rolling element bearing member designed for use in a preselected bearing operation, such as a gas turbine engine, which develops a predetermined operating hoop tensile stress in the member includes a hardened layer contiguous with a ductile core having a hardness less than 50 Rockwell C. For example, the hardened layer is a carburized layer of high hardness in the range of 58-66 Rockwell C. The hardened layer has improved resistance to crack initiation and propagation as a result of providing the layer with compressive residual stress in an amount greater than the predetermined operating hoop tensile stress, for example in the range of about 10-60 ksi to a depth up to about 0.06 inch. Such a member is made by providing a member of a metal alloy having the capability of developing such a hardened layer, and then processing the member to develop the layer in the amount of compression.
    Type: Grant
    Filed: February 25, 1985
    Date of Patent: April 21, 1987
    Assignee: General Electric Company
    Inventors: Eric N. Bamberger, John C. Clark, Jr., Alexander H. Nahm
  • Patent number: 4569070
    Abstract: The rotor that carries the target in a rotating anode x-ray tube is carried on a shaft that is journaled in axially spaced apart ball bearings. The outer and inner races of the bearings have curved grooves presented toward each other and there are a plurality of balls in the grooves. A preloaded spring is interposed between corresponding races of the bearings for applying oppositely directed axial forces to them. The grooves are so shaped and the clearance between the balls and groove surfaces is such that when the axial force is applied, one race shifts axially relative to the other in which case each ball has two points of contact, one point at which the ball contacts the surface of the groove in the outer race on one side of a plane transverse to the shaft axis and another point where the ball contacts the surface of the groove in the inner race on the other side of the plane.
    Type: Grant
    Filed: September 19, 1983
    Date of Patent: February 4, 1986
    Assignee: General Electric Company
    Inventors: Thomas E. Schubert, John C. Clark