Patents by Inventor John C. Vederas

John C. Vederas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds that stimulate glucose utilization and methods of use
    Patent number: 8202901
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: June 19, 2012
    Assignee: The Governors of the University of Alberta
    Inventors: Gary D. Lopaschuk, John C. Vederas, Jason R. Dyck
  • Novel Bacteriocins, Transport and Vector System and Method of Use Thereof
    Publication number: 20100129864
    Abstract: New bacteriocins capable of inhibiting the growth of bacteria are disclosed, along with methods of obtaining secretion of proteins from lactic acid bacteria, and methods for protecting foodstuffs.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 27, 2010
    Inventors: Michael E. Stiles, John C Vederas, Marius J van Belkum, Randy W Worobo, Rodney J Worobo, John K McCormick, Gordon G. Greer, Lynn M McMullen, Jorgen J Leisner, Alison Poon, Charles M.A.P. Franz
  • COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE
    Publication number: 20090258835
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: March 12, 2009
    Publication date: October 15, 2009
    Applicant: The Governors of the University of Alberta TEC Edmonton
    Inventors: Gary D. Lopaschuk, John C. Vederas, Jason R. Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Patent number: 7524885
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: April 28, 2009
    Assignee: The Governors of the University of Alberta
    Inventors: Gary D. Lopaschuk, John C Vederas, Jason R. Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Patent number: 7473706
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: January 6, 2009
    Assignee: The Governors of the University of Alberta
    Inventors: Gary D. Lopaschuk, John C. Vederas, Jason R. Dyck
  • Novel bacteriocins, transport and vector system and method of use thereof
    Publication number: 20030039632
    Abstract: New bacteriocins capable of inhibiting the growth of bacteria are disclosed, along with methods of obtaining secretion of proteins from lactic acid bacteria, and methods for protecting foodstuffs.
    Type: Application
    Filed: June 19, 2001
    Publication date: February 27, 2003
    Inventors: Michael E. Stiles, John C. Vederas, Marius J. Van Belkum, Randy W. Worobo, Rodney J. Worobo, John K. McCormick, Gordon G. Greer, Lynn M. McMullen, Jorgen J. Leisner, Alison Poon, Charles M.A.P. Franz
  • Bacteriocins, transport and vector system and method of use thereof
    Patent number: 6403082
    Abstract: New bacteriocins capable of inhibiting the growth of bacteria are disclosed, along with methods of obtaining secretion of proteins from lactic acid bacteria, and methods for protecting foodstuffs.
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: June 11, 2002
    Inventors: Michael E. Stiles, John C. Vederas, Marius J. Van Belkum, Randy W. Worobo, Rodney J. Worobo, John K. McCormick, G. Gordon Greer, Lynn M. McMullen, Jorgen J. Leisner, Alison Poon, Charles M. A. P. Franz
  • Syntheses of optically pure .alpha.-amino acids from 3-amino-2-oxetanone salts
    Patent number: 5200526
    Abstract: A process for the preparation of optically pure .alpha.-amino acids comprising the nucleophilic ring-opening of 3-amino-2-oxetanone salts. N-Protected serine .beta.-lactones are deprotected to form heretofore unknown 3-amino-2-oxetanone and its corresponding salts. In turn these previously unknown 3-amino-2-oxetanone salts may be used in the synthesis of other novel or rare stereochemically-pure free amino acids.
    Type: Grant
    Filed: October 23, 1990
    Date of Patent: April 6, 1993
    Assignee: The Governors of the University of Alberta
    Inventors: Lee D. Arnold, John C. Vederas
  • Polymer-supported alkyl azodicarboxylates and their use in Mitsunobu reactions
    Patent number: 4960832
    Abstract: A process for preparing an azodicarboxylate composition by chemically bonding dialkyl azodicarboxylates onto an insoluble solid polymer support. This process comprises the immobilization of hydrazodicarboxylates onto an insoluble solid polymer support and oxidizing the hydrazodicarboxylates to azodicarboxylates. The azodicarboxylate-polymer composition may be used in Mitsunobu-type reactions. After use in Mitsunobu-type reactions, the azodicarboxylate-polymer composition is recoverable and may be reused.
    Type: Grant
    Filed: April 27, 1988
    Date of Patent: October 2, 1990
    Assignee: The Governors of the University of Alberta
    Inventors: Lee D. Arnold, John C. Vederas