Patents by Inventor John Colin Emmett

John Colin Emmett has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzyl pyridyl and pyridazinyl compounds
    Patent number: 5061798
    Abstract: This invention relates to chemical compounds which have selective thyromimetic activity. A compound of this invention is 3,5-dibromo-3'-[6-oxo-3)1H)-pyridazinylmethyl)-thyronine.
    Type: Grant
    Filed: October 27, 1989
    Date of Patent: October 29, 1991
    Assignee: Smith Kline & French Laboratories, Ltd.
    Inventors: John Colin Emmett, Paul D. Leeson
  • Pharmacologically active compounds
    Patent number: 4104381
    Abstract: Heterocyclic compounds which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A specific compound of this invention is 2-[2-(4-methyl-5-imidazolylmethylthio)ethylamino]-4-pyrimidone.
    Type: Grant
    Filed: October 29, 1976
    Date of Patent: August 1, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Process for preparing heterocyclicalkylthioalkyl-N-cyanoguanidines and thioureas
    Patent number: 4093621
    Abstract: Process for preparing heterocyclicalkylthioalkyl-N-cyanoguanidines and thioureas by treating a heterocyclicalkyl derivative with a mercaptoalkyl-N-cyanoguanidine or thiourea. Two specific products are N-cyano-N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidine and N-methyl-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]thiourea, both useful as histamine H.sub.2 -antagonists.
    Type: Grant
    Filed: November 15, 1976
    Date of Patent: June 6, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Thomas Henry Brown, Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmacologically active compounds
    Patent number: 4083988
    Abstract: The compounds are guanidines, for example N-benzenesulphonyl-N'-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidi ne, which are inhibitors of histamine activity.
    Type: Grant
    Filed: September 24, 1976
    Date of Patent: April 11, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pyridyl-alkylaminoethylene compounds
    Patent number: 4080459
    Abstract: The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-[2-((4-methyl-5-imidazolyl)methylthio)ethylamino]2-[2-((3-chloro -2-pyridyl)methylthio)ethylamino]ethylene.
    Type: Grant
    Filed: November 19, 1976
    Date of Patent: March 21, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin, Hunter Douglas Prain
  • Pharmacologically active guanidine compounds as H-2 histamine receptor inhibitors
    Patent number: 4070475
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl-, and oxyalkyl-guanidines which are inhibitors of histamine activity.
    Type: Grant
    Filed: February 2, 1977
    Date of Patent: January 24, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmacologically active thiourea and urea compounds as inhibitors of H-2 histamine receptors
    Patent number: 4069327
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
    Type: Grant
    Filed: January 5, 1977
    Date of Patent: January 17, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pyridylbutylamino ethylene compounds
    Patent number: 4067984
    Abstract: The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[4-(3-chloro-2-pyridyl)butylamino]ethylene.
    Type: Grant
    Filed: October 4, 1976
    Date of Patent: January 10, 1978
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin, Hunter Douglas Prain
  • Pyridyl alkylguanidine compounds
    Patent number: 4060621
    Abstract: The compounds are pyridyl alkylguanidines, fo example N-benzenesulphonyl-N'-methyl-N"-[2-((3-hydroxy-2-pyridyl)methylthio)ethyl] guanidine, which are inhibitors of histamine activity.
    Type: Grant
    Filed: April 5, 1976
    Date of Patent: November 29, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmacologically active thiourea and urea compounds
    Patent number: 4053473
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
    Type: Grant
    Filed: December 5, 1975
    Date of Patent: October 11, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • 4-Methyl-5-imidazolylmethylthioethylamine and -S-methylisothiourea
    Patent number: 4049672
    Abstract: The compounds are heterocyclic thioalkyl-, aminoalkyl- and oxyalkylguanidines which are inhibitors of histamine activity, particularly inhibitors of H-2 histamine receptors.
    Type: Grant
    Filed: March 17, 1976
    Date of Patent: September 20, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Method of inhibiting histamine activity with quanidine compounds
    Patent number: 4048319
    Abstract: A method of inhibiting histamine activity, in particular inhibiting H-2 histamine receptors, by administering heterocyclicalkylguanidines.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: September 13, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: James Whyte Black, Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Imidazole alkylaminoethylene compounds
    Patent number: 4046907
    Abstract: The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[2-((4-methyl-5-imidazolyl)methylthio)-ethylamino] ethylene.
    Type: Grant
    Filed: November 5, 1975
    Date of Patent: September 6, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin, Hunter Douglas Prain
  • Imidazolyl alkylaminopyridone and pyridinethione compounds
    Patent number: 4035374
    Abstract: Heterocyclic compounds which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A specific compound of this invention is 2-[2-(4-methyl-5-imidazolylmethylthio)ethylamino]-4-pyrimidone.
    Type: Grant
    Filed: October 6, 1975
    Date of Patent: July 12, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmaceutical compositions and methods of inhibiting H-2 histamine receptors with pyridyl substituted thioalkyl- and oxyalkyl-thioureas and ureas
    Patent number: 4027026
    Abstract: Pharmaceutical compositions and methods of inhibiting H-2 histamine receptors with pyridyl substituted thioalkyl- and oxyalkyl-thioureas and ureas.
    Type: Grant
    Filed: June 13, 1975
    Date of Patent: May 31, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmacologically active guanidine compounds
    Patent number: 4024271
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-guanidines which are inhibitors of histamine activity.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: May 17, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Ethylene derivatives
    Patent number: 4024260
    Abstract: The compounds are ethylene derivatives which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A compound of this invention is 1-nitro-2-methylamino-2-[2-((4-methyl-5-imidazolyl)methylthio)-ethylamino[ ethylene.
    Type: Grant
    Filed: November 11, 1975
    Date of Patent: May 17, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin, Hunter Douglas Prain
  • Certain thiazole, isothiazole, oxazole, and isoxazole compounds
    Patent number: 4022797
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-guanidines which are inhibitors of histamine activity.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: May 10, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pyridyl substituted aminoalkyl-thioureas and ureas
    Patent number: 4018928
    Abstract: The compounds are pyridyl substituted aminoalkylthioureas and ureas which are inhibitors of H-2 histamine receptors. A compound of this invention is N-methyl-N'-[2-(2-pyridylmethylamino)ethyl]thiourea.
    Type: Grant
    Filed: October 29, 1975
    Date of Patent: April 19, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin
  • Pharmacologically active thiourea and urea compounds
    Patent number: 4018931
    Abstract: The compounds are substituted thioalkyl-, aminoalkyl- and oxyalkyl-thioureas and ureas which are inhibitors of histamine activity.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: April 19, 1977
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Graham John Durant, John Colin Emmett, Charon Robin Ganellin