Abstract: Embodiments described herein relate to blended meat substitute products and methods of producing the same. In some aspects, a method of producing a meat substitute product can include providing a plant based scaffolding with a carrier material, the carrier material including animal cells, adding a gelation agent to at least one of the plant-based scaffolding, and incubating the carrier material and the plant-based scaffolding in a controlled environment to produce a meat substitute product. In some embodiments, the animal cells can include at least one of skeletal muscle cells, fat cells, connective tissue cells, or skin cells.

Abstract: A dynamic exercise device having a base, a handle rotatably mounted in the base, and a stand which supports the base, the base being mounted in the stand via a sliding joint. In a first mode of use, the stand is detached and the base is placed against a surface on which the exercise device is used, and in a second mode of use, the stand is attached to the base such that in the second mode of use the stand is placed against the surface on which the exercise device is used.

Abstract: A dynamic exercise device having a hand grip mounted in an inner ring, the inner ring mounted in an outer ring, and the outer ring mounted in a base. The inner ring, outer ring and base are each movable in at least one degree of freedom relative to each of the others. The base further includes a first support strut, a second support strut, and a bridge member interconnecting the first and second support struts and having a planar surface-engaging face configured to engage a surface on or against which the exercise device is used.

Abstract: The present invention relates to receptor tyrosine kinase-like orphan receptor 1 (ROR1) specific antigen binding molecules and associated fusion proteins and conjugates. In a further aspect, the present invention relates to conjugated immunoglobulin-like shark variable novel antigen receptors (VNARs).

Abstract: A dynamic exercise device having a hand grip mounted in an inner ring, the inner ring mounted in an outer ring, and the outer ring mounted in a base. Each of the above elements is movable in at least one degree of freedom relative to each of the other elements. Optionally, the base has feet. The feet may be fixed elements that provide immobility, or dynamic elements, such as roller bearings, that may provide adjustable movement.

Abstract: A process of hydrogen production comprising the steps of: subjecting a gaseous mixture comprising a hydrocarbon and steam, and having a steam to carbon ratio of at least 0.9:1, to adiabatic pre-reforming in a pre-reformer followed by autothermal reforming with an oxygen-rich gas in an autothermal reformer to generate a reformed gas mixture, optionally adding steam to the reformed gas mixture, increasing the hydrogen content of the reformed gas mixture by subjecting it to one or more water-gas shift stages in a water-gas shift unit to provide a hydrogen-enriched reformed gas, cooling the hydrogen-enriched reformed gas and separating condensed water therefrom, passing the resulting de-watered hydrogen-enriched reformed gas to a carbon dioxide separation unit to provide a carbon dioxide gas stream and a crude hydrogen gas stream, passing the crude hydrogen gas stream to a purification unit to provide a purified hydrogen gas and a fuel gas.

Abstract: A process for the production of hydrogen comprising the steps of subjecting a gaseous mixture comprising a hydrocarbon and steam and having a steam to carbon ratio of at least 2.6:1, to steam reforming in a gas-heated reformer followed by autothermal reforming with an oxygen-rich gas in an autothermal reformer to generate a reformed gas mixture, increasing the hydrogen content of the reformed gas mixture by subjecting it to one or more water-gas shift stages in a water-gas shift unit to provide a hydrogen-enriched reformed gas, cooling the hydrogen-enriched reformed gas and separating condensed water therefrom, passing the resulting de-watered hydrogen-enriched reformed gas to a carbon dioxide separation unit to provide a carbon dioxide gas stream and a crude hydrogen gas stream, and passing the crude hydrogen gas stream to a purification unit to provide a purified hydrogen gas and a fuel gas.

Abstract: A multi-functional exercise device that enables a user to exercise different muscle groups. The exercise device has a first planar support member, a second planar support member extending from the first planar support member, and a handle having a first end coupled to the first planar support member, a second end coupled to the second planar support member, and a gripping portion therebetween. The gripping portion of the handle is oriented generally parallel to the first planar support member and generally perpendicular to the second planar support member. The exercise device also includes a first plurality of rotatable components engaging the first planar support member and adapted to rotate relative thereto, and a second plurality of rotatable components engaging the second planar support member and adapted to rotate relative thereto. The rotatable elements may comprise spheres.

Abstract: A medical implant for treating a shoulder joint. The implant includes a humeral head attachment region configured to be attached to a humeral head of the shoulder joint, a glenoid attachment region configured to be attached to a glenoid of the shoulder joint, and a rotator cuff tendon attachment region configured to be attached to a rotator cuff tendon of the shoulder joint.

Abstract: A bioactive scaffold for use in reconstruction of an anterior cruciate ligament of a patient, may include a tissue matrix configured to wrap around a graft configured to extend from a first bone of a joint to a second bone of the joint. The tissue matrix may include collagen type I. The tissue matrix may include a first plurality of apertures extending through the tissue matrix along a first edge of the tissue matrix and a second plurality of apertures extending through the tissue matrix along a second edge of the tissue matrix. At least one filament may be configured to be laced through the first plurality of apertures and the second plurality of apertures and draw the first edge of the tissue matrix toward the second edge of the tissue matrix when the at least one filament is subjected to tension thereby closing the tissue matrix around the graft.

Abstract: A dynamic exercise device having a hand grip mounted in an inner ring, the inner ring mounted in an outer ring, and the outer ring mounted in a base. Each of the above elements in movable in at least one degree of freedom relative to each of the other elements. Optionally, the base has feet. The feet may be fixed elements that provide immobility, or dynamic elements, such as roller bearings, that may provide adjustable movement.

Abstract: A multi-functional exercise device that enables a user to exercise different muscle groups. The exercise device has a a first planar support member, a second planar support member extending from the first planar support member at an angle therebetween, and a handle coupled to the first planar support member and to the second planar support member. The handle has an elongated gripping portion that is oriented generally parallel to the first planar support member and generally perpendicular to the second planar support member. The exercise device is configured to be alternated between a first orientation in which the first planar support member is positioned against a surface, and a second orientation in which the second planar support member is positioned against the surface.

Abstract: A multi-functional exercise device that enables a user to exercise different muscle groups. The exercise device has a first planar support member, a second planar support member extending from the first planar support member, and a handle having a first end coupled to the first planar support member, a second end coupled to the second planar support member, and a gripping portion therebetween. The gripping portion of the handle is oriented generally parallel to the first planar support member and generally perpendicular to the second planar support member. The exercise device also includes a first plurality of rotatable components engaging the first planar support member and adapted to rotate relative thereto, and a second plurality of rotatable components engaging the second planar support member and adapted to rotate relative thereto. The rotatable elements may comprise spheres.

Abstract: The present invention relates to bi-specific antigen binding molecules and associated fusion proteins and conjugates. In particular, the present invention relates to bi-specific antigen binding molecules with specificity for both receptor tyrosine kinase-like orphan receptor 1 (ROR1) and epidermal growth factor receptor (EGFR) and associated fusion proteins and conjugates. In a further aspect, the present invention relates to conjugated immunoglobulin-like shark variable novel antigen receptors (VNARs).

Abstract: Described are systems and methods for dynamically generating advertisements for presentation in an application executing on a client device, such as an application executing on a smart phone or tablet of a user. The described systems and methods select content items of specific content types based on determined user preference for content types as well as the device capabilities and access permissions of the application through which the advertisement is to be presented.

Abstract: Described are systems and methods for dynamically generating advertisements for presentation in an application executing on a client device, such as an application executing on a smart phone or tablet of a user. The described systems and methods select content items of specific content types based on determined user preference for content types as well as the device capabilities and access permissions of the application through which the advertisement is to be presented.

Abstract: A multi-functional exercise device that enables a user to exercise different muscle groups. The exercise device has a handle and two surface-engaging members connected to the handle, allowing for multiple orientations for use.

Abstract: Described are systems and methods for dynamically generating advertisements for presentation in an application executing on a client device, such as an application executing on a smart phone or tablet of a user. The described systems and methods select content items of specific content types based on determined user preference for content types as well as the device capabilities and access permissions of the application through which the advertisement is to be presented.

Abstract: A method of repairing a partial or complete ACL tear using a biologically active suture combined with a suture anchor. The biologically active material may be an angiogenic material that provides a biological stimulus (such as blood vessel growth) to initiate the repair cascade throughout the tear.

Abstract: Support panels for masonry objects and associated methods of use are disclosed herein. A support panel for masonry objects may include an inner surface, an outer surface, at least one stiffening channel formed longitudinally along the support panel, and a plurality of substantially C-shaped tabs extending from the outer surface, the tabs being disposed in spaced apart relation to one another to form a grid, wherein the tabs are configured to contactingly support at least a portion of a masonry object.