Abstract: The disclosure relates to a sterilization apparatus which uses thermal or non-thermal plasma to disinfect surgical scoping devices such as endoscopes, gastroscopes, laparoscopes and the like. Aspect of the disclosure provide: (i) an apparatus for sterilizing inside an instrument channel formed with an insertion tube of a surgical scoping device, (ii) a whole-device sterilization apparatus for treating the entire exterior surface of a surgical scoping device, and (iii) an apparatus for cleaning and sterilizing a distal end face of an insertion tube of a surgical scoping device.

Abstract: Disclosed are methods of synthesis and/or purification of certain 3,7-diamino-phenothiazin-5-ium compounds (“diaminophenothiazinium compounds”) including Methylthioninium Chloride (MTC) (Methylene Blue), and the resulting high purity characterized by a purity greater than 98%, and very low levels of heavy metals and organic impurities Azure A, B, C and MVB. Also disclosed are methods of treatment of a tauopathy or methemoglobinemia in a patient in need thereof, comprising administering to the patient a therapeutically effective amount of the high-purity diaminophenothiazinium compound.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: Described are methods of preparing reduced 3,7-diamino-10H-phenothiazine (DAPTZ) compounds of formula: wherein: R1 and R9 are independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R3NA and R3NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of R7NA and R7NB is independently selected from: —H; C1-4alkyl; C2-4alkenyl; and halogenated C1-4alkyl; each of HX1 and HX2 is independently a protic acid; and pharmaceutically acceptable salts, solvates, and hydrates thereof. These methods are particularly useful for producing stable reduced forms, and with high purity. The stability and purity are especially relevant for pharmaceutical compositions for the treatment of disease. The compounds are useful for treatment of e.g. tauopathies, such as Alzheimer's disease, and also as prodrugs for the corresponding oxidized thioninium drugs.

Abstract: The invention provides an adjustable stiffness assembly for use in conjunction with a fixed stiffness element to elastically connect a structure to a mass. The assembly includes a structure mount, a mass mount, and a rotatable stiffness element. The rotatable stiffness element rotatably engages with the structure mount and the mass mount, and has a minimum stiffness value with respect to forces in a direction a maximum stiffness value with respect to forces in another direction The fixed stiffness element and the adjustable stiffness assembly together provide a complete stiffness assembly having a total stiffness value with respect to force in the global direction for elastically connecting the mass and the structure. The first rotatable stiffness element is rotatable relative to the structure mount and the first mass mount to vary the total stiffness value of the complete stiffness assembly with respect to force in the global direction.

Abstract: The present invention relates to powdered beverages. In particular to a powdered beverage comprising glycolipids and a fat having a melting point above 20° C. Further aspects of the invention are a process for manufacturing a powdered beverage and the use of glycolipids to reduce the reconstitution time of a beverage powder, for example after storage.

Abstract: A method of forming end-form structures from recycled plastics includes i) providing molten agglomerated plastics in noodle form; ii) delivering the molten agglomerated plastics to a shaper; iii) forming an end-form of agglomerated plastics in the shaper by controlling movement and/or position of the shaper, the end-form comprising the agglomerated plastics welded together with voids therebetween; and iv) cooling at least an outer profile of the end-form to form the structure.

Abstract: The invention provides an adjustable stiffness assembly for use in conjunction with a fixed stiffness element to elastically connect a structure to a mass. The assembly includes a structure mount, a mass mount, and a rotatable stiffness element. The rotatable stiffness element rotatably engages with the structure mount and the mass mount, and has a minimum stiffness value with respect to forces in a direction a maximum stiffness value with respect to forces in another direction The fixed stiffness element and the adjustable stiffness assembly together provide a complete stiffness assembly having a total stiffness value with respect to force in the global direction for elastically connecting the mass and the structure. The first rotatable stiffness element is rotatable relative to the structure mount and the first mass mount to vary the total stiffness value of the complete stiffness assembly with respect to force in the global direction.

Abstract: A sports field has a stable, impermeable substrate, a water distributing layer provided over the substrate and an artificial turf layer over the water distributing layer. A bund defines a perimeter of the sports field and extends from the substrate to at least the height of the artificial turf layer. A drain channel having inlets at a height to communicate with the water distributing layer is provided such that water can flow from the water distributing layer into the drain channel and vice versa. As a result of this constructions, there is formed a containment, defined by the bund surrounding the field and by the substrate. Water can be held within the containment in the water distributing layer allowing for water attenuation and cooling of the sports field.

Abstract: A method of forming end-form structures from recycled plastics includes i) providing molten agglomerated plastics in noodle form; ii) delivering the molten agglomerated plastics to a shaper; iii) forming an end-form of agglomerated plastics in the shaper by controlling movement and/or position of the shaper, the end-form comprising the agglomerated plastics welded together with voids therebetween; and iv) cooling at least an outer profile of the end-form to form the structure.

Abstract: A method of forming a substrate for a sports surface of a sports pitch includes the steps of: a) Agglomerating plastics materials; b) Granulating the agglomerated plastics materials to form granules having a predetermined range of sizes; c) In situ coating the granules with a binding material so that they form a fluent material; d) Forming a layer of the fluent material on the site of the sports pitch; and e) Setting the laid material such that the granules adhere where they contact each other to form a voided water permeable structure.

Abstract: A variable stator vane arrangement includes a casing, a plurality of stator vanes, at least one control ring, a plurality of connecting rods and a crankshaft. The stator vanes are circumferentially spaced apart in the casing and the plurality of stator vanes are rotatably mounted in the casing. Each control ring is rotatably mounted on the casing and each stator vane is connected to an associated control ring. The crankshaft, rotatably mounted on the casing, is drivingly connected to each control ring and has an axis and a plurality of clevizes. Each connecting rod connects one of the clevizes on the crankshaft to a respective one of the control rings. At least one clevis is adjustably secured to the crankshaft by an adjusting mechanism and the adjusting mechanism is used to select the radial and/or angular position of at least one clevis relative to the axis of the crankshaft.

Abstract: The invention provides an adjustable stiffness assembly for use in conjunction with a fixed stiffness element to elastically connect a structure to a mass. The assembly includes a structure mount, a mass mount, and a rotatable stiffness element. The rotatable stiffness element rotatably engages with the structure mount and the mass mount, and has a minimum stiffness value with respect to forces in a direction a maximum stiffness value with respect to forces in another direction The fixed stiffness element and the adjustable stiffness assembly together provide a complete stiffness assembly having a total stiffness value with respect to force in the global direction for elastically connecting the mass and the structure. The first rotatable stiffness element is rotatable relative to the structure mount and the first mass mount to vary the total stiffness value of the complete stiffness assembly with respect to force in the global direction.

Abstract: A sports field has a stable, impermeable substrate, a water distributing layer provided over the substrate and an artificial turf layer over the water distributing layer. A bund defines a perimeter of the sports field and extends from the substrate to at least the height of the artificial turf layer. A drain channel having inlets at a height to communicate with the water distributing layer is provided such that water can flow from the water distributing layer into the drain channel and vice versa. As a result of this constructions, there is formed a containment, defined by the bund surrounding the field and by the substrate. Water can be held within the containment in the water distributing layer allowing for water attenuation and cooling of the sports field.

Abstract: A method of forming a substrate for a sports surface of a sports pitch includes the steps of: a) Agglomerating plastics materials; b) Granulating the agglomerated plastics materials to form granules having a predetermined range of sizes; c) In situ coating the granules with a binding material so that they form a fluent material; d) Forming a layer of the fluent material on the site of the sports pitch; and e) Setting the laid material such that the granules adhere where they contact each other to form a voided water permeable structure.

Abstract: A method of forming a substrate for a sports surface of a sports pitch includes the steps of: a) Agglomerating plastics materials; b) Granulating the agglomerated plastics materials to form granules having a predetermined range of sizes; c) In situ coating the granules with a binding material so that they form a fluent material; d) Forming a layer of the fluent material on the site of the sports pitch; and e) Setting the laid material such that the granules adhere where they contact each other to form a voided water permeable structure.

Abstract: A variable stator vane arrangement includes a casing, a plurality of stator vanes, at least one control ring, a plurality of connecting rods and a crankshaft. The stator vanes are circumferentially spaced apart in the casing and the plurality of stator vanes are rotatably mounted in the casing. Each control ring is rotatably mounted on the casing and each stator vane is connected to an associated control ring. The crankshaft, rotatably mounted on the casing, is drivingly connected to each control ring and has an axis and a plurality of clevises. Each connecting rod connects one of the clevises on the crankshaft to a respective one of the control rings. At least one clevis is adjustably secured to the crankshaft by an adjusting mechanism and the adjusting mechanism is used to select the radial and/or angular position of at least one clevis relative to the axis of the crankshaft.

Abstract: A method of forming a substrate for a sports surface of a sports pitch includes the steps of: a) Agglomerating plastics materials; b) Granulating the agglomerated plastics materials to form granules having a predetermined range of sizes; c) In situ coating the granules with a binding material so that they form a fluent material; d) Forming a layer of the fluent material on the site of the sports pitch; and e) Setting the laid material such that the granules adhere where they contact each other to form a voided water permeable structure.

Abstract: The invention provides 1,3-DAGs with melting point ranges of from about 32° C. to about 37° C. for use in a variety of hard fat applications and in particular for the preparation of a cocoa butter substitute for confectionery use. The invention contemplates novel 1,3-DAGs, cocoa butter substitute incorporating such 1,3-DAG compounds, confectionery products and shortenings containing both and methods of making such.

Abstract: A beam device, in particular a particle beam device, for analyzing an object is provided, as well as a system comprising a particle beam device and an optical microscope for optically analyzing an object. The beam device simplifies the exchange and reduces the time of the exchange of objects to be examined. The beam device includes at least one beam generator that generates a beam, at least one objective lens that focuses the beam on an object arranged in a holding element. The objective lens comprises at least one connecting element. The holding element may be connected to the connecting element so that the holding element is removable from the connecting element for modification of the object. Alternatively, the holding element may be mounted to a beam column.