Patents by Inventor John D. Huber
John D. Huber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9745297Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.Type: GrantFiled: July 28, 2014Date of Patent: August 29, 2017Assignee: Boehringer Ingelheim International GmbHInventors: Brian Nicholas Cook, John D. Huber, Robert Owen Hughes, Xiang Li, Shuang Liang, Ingo Andreas Mugge, Michael Robert Turner, Qiang Zhang
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Patent number: 9745267Abstract: The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.Type: GrantFiled: September 4, 2014Date of Patent: August 29, 2017Assignee: Boehringer Ingelheim International GmbHInventors: Brian Nicholas Cook, John D. Huber, Robert Owen Hughes, Thomas Martin Kirrane, Jr., Celina Lasota, Xiang Li, Shuang Liang, Ingo Andreas Mugge, Qiang Zhang
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Publication number: 20160251310Abstract: The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.Type: ApplicationFiled: September 4, 2014Publication date: September 1, 2016Inventors: Brian COOK, John d. HUBER, Robert Owen HUGHES, Thomas Martin KIRRANE, JR., Celina LASOTA, Xiang LI, Shuang LIANG, Andreas MUGGE, Qiang ZHANG
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Publication number: 20160159791Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.Type: ApplicationFiled: July 28, 2014Publication date: June 9, 2016Inventors: Brian Nicholas COOK, John D. HUBER, Robert Owen HUGHES, Xiang LI, Shuang LIANG, Ingo Andreas MUGGE, Michael Robert TURNER, Qiang ZHANG
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Patent number: 8871786Abstract: Disclosed are CCR1 inhibitor compounds of the formula (I): which are useful in the treatment of autoimmune and other diseases. Also disclosed a pharmaceutical compositions containing the same, and methods of making and using same.Type: GrantFiled: April 26, 2011Date of Patent: October 28, 2014Assignee: Boehringer Ingelheim International GmbHInventor: John D. Huber
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Patent number: 8658661Abstract: The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: GrantFiled: August 12, 2011Date of Patent: February 25, 2014Assignee: Boehringer Ingelheim International GmbHInventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, John D. Huber, Ho Yin Lo, Pui Leng Loke, Weimin Liu, Tina Marie Morwick, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
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Patent number: 8601938Abstract: The baby formula preparation device includes a powder hopper and a distributor operably associated with the powder hopper for dispensing powdered baby formula into a baby bottle. The device also includes a water dispensing system having a water storage tank and a water heater that dispenses heated water into the baby bottle. A load cell measures the weight of the bottle and a controller coupled to the load cell regulates the quantity by weight of heated water and powdered baby formula dispensed into the baby bottle.Type: GrantFiled: January 17, 2008Date of Patent: December 10, 2013Inventors: John D. Huber, Jennifer DiLorenzo
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Patent number: 8580825Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: GrantFiled: September 20, 2011Date of Patent: November 12, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, John D. Huber, Weimin Liu, Ho Yin Lo, Pui Leng Loke, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
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Patent number: 8580829Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: GrantFiled: August 23, 2011Date of Patent: November 12, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, Jonathon Alan Dines, John D. Huber, Weimin Liu, Ho Yin Lo, Pui Leng Loke, Tina Marie Morwick, Peter Allen Nemoto, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
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Patent number: 8575201Abstract: The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: GrantFiled: September 20, 2011Date of Patent: November 5, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, Jonathon Alan Dines, John D. Huber, Weimin W. Liu, Pui Leng Loke, Tina Marie Morwick, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
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Patent number: 8569339Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A and B are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: GrantFiled: March 8, 2012Date of Patent: October 29, 2013Assignee: Boehringer Ingelheim International GmbHInventors: Jehrod Burnett Brenneman, John D. Huber, Brian Christopher Raudenbush, Christopher Ronald Sarko
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Publication number: 20130203803Abstract: Disclosed are CCR1 inhibitor compounds of the formula (I): which are useful in the treatment of autoimmune and other diseases. Also disclosed a pharmaceutical compositions containing the same, and methods of making and using same.Type: ApplicationFiled: April 26, 2011Publication date: August 8, 2013Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventor: John D. Huber
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Publication number: 20130065918Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A and B are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: ApplicationFiled: March 8, 2012Publication date: March 14, 2013Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Jehrod Burnett Brenneman, John D. Huber, Brian Christopher Raudenbush, Christopher Ronald Sarko
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Publication number: 20120295896Abstract: The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: ApplicationFiled: September 20, 2011Publication date: November 22, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, John D. HUBER, Weimin W. LIU, Pui Leng LOKE, Tina Marie MORWICK, Alan OLAGUE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
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Publication number: 20120245162Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein.Type: ApplicationFiled: September 20, 2011Publication date: September 27, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
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Publication number: 20120220561Abstract: The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: ApplicationFiled: August 12, 2011Publication date: August 30, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Ho Yin LO, Pui Leng LOKE, Weimin LIU, Tina Marie MORWICK, Alan OLAGUE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
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Publication number: 20120214787Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.Type: ApplicationFiled: August 23, 2011Publication date: August 23, 2012Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBHInventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Tina Marie MORWICK, Peter Allen NEMOTO, Alan OLAGUE, Doris RIETHER, Heather Tye, Lifen WU, Renee M. ZINDELL
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Publication number: 20110131655Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).Type: ApplicationFiled: November 30, 2010Publication date: June 2, 2011Applicant: Cisco Technology, Inc.Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi
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Patent number: 7873833Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).Type: GrantFiled: June 29, 2006Date of Patent: January 18, 2011Assignee: Cisco Technology, Inc.Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi
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Publication number: 20080022106Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).Type: ApplicationFiled: June 29, 2006Publication date: January 24, 2008Applicant: CiSCO TECHNOLOGY, INC.Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi