Patents by Inventor John D. Huber

John D. Huber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9745297
    Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
    Type: Grant
    Filed: July 28, 2014
    Date of Patent: August 29, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Brian Nicholas Cook, John D. Huber, Robert Owen Hughes, Xiang Li, Shuang Liang, Ingo Andreas Mugge, Michael Robert Turner, Qiang Zhang
  • Patent number: 9745267
    Abstract: The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
    Type: Grant
    Filed: September 4, 2014
    Date of Patent: August 29, 2017
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Brian Nicholas Cook, John D. Huber, Robert Owen Hughes, Thomas Martin Kirrane, Jr., Celina Lasota, Xiang Li, Shuang Liang, Ingo Andreas Mugge, Qiang Zhang
  • Publication number: 20160251310
    Abstract: The present invention encompasses compounds of the formula (I): wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
    Type: Application
    Filed: September 4, 2014
    Publication date: September 1, 2016
    Inventors: Brian COOK, John d. HUBER, Robert Owen HUGHES, Thomas Martin KIRRANE, JR., Celina LASOTA, Xiang LI, Shuang LIANG, Andreas MUGGE, Qiang ZHANG
  • Publication number: 20160159791
    Abstract: The present invention encompasses compounds of the formula (I), wherein the variables are defined herein which are suitable for the modulation of RORC and the treatment of diseases related to the modulation of RORC. The present invention also encompasses processes of making compounds of formula (I) and pharmaceutical preparations containing them.
    Type: Application
    Filed: July 28, 2014
    Publication date: June 9, 2016
    Inventors: Brian Nicholas COOK, John D. HUBER, Robert Owen HUGHES, Xiang LI, Shuang LIANG, Ingo Andreas MUGGE, Michael Robert TURNER, Qiang ZHANG
  • Patent number: 8871786
    Abstract: Disclosed are CCR1 inhibitor compounds of the formula (I): which are useful in the treatment of autoimmune and other diseases. Also disclosed a pharmaceutical compositions containing the same, and methods of making and using same.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: October 28, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventor: John D. Huber
  • Patent number: 8658661
    Abstract: The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: February 25, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, John D. Huber, Ho Yin Lo, Pui Leng Loke, Weimin Liu, Tina Marie Morwick, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
  • Patent number: 8601938
    Abstract: The baby formula preparation device includes a powder hopper and a distributor operably associated with the powder hopper for dispensing powdered baby formula into a baby bottle. The device also includes a water dispensing system having a water storage tank and a water heater that dispenses heated water into the baby bottle. A load cell measures the weight of the bottle and a controller coupled to the load cell regulates the quantity by weight of heated water and powdered baby formula dispensed into the baby bottle.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: December 10, 2013
    Inventors: John D. Huber, Jennifer DiLorenzo
  • Patent number: 8580825
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: November 12, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, John D. Huber, Weimin Liu, Ho Yin Lo, Pui Leng Loke, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
  • Patent number: 8580829
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: August 23, 2011
    Date of Patent: November 12, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, Jonathon Alan Dines, John D. Huber, Weimin Liu, Ho Yin Lo, Pui Leng Loke, Tina Marie Morwick, Peter Allen Nemoto, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
  • Patent number: 8575201
    Abstract: The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: November 5, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Alessandra Bartolozzi, Todd Bosanac, Zhidong Chen, Stephane De Lombaert, Jonathon Alan Dines, John D. Huber, Weimin W. Liu, Pui Leng Loke, Tina Marie Morwick, Alan Olague, Doris Riether, Heather Tye, Lifen Wu, Renee M. Zindell
  • Patent number: 8569339
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A and B are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: October 29, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Jehrod Burnett Brenneman, John D. Huber, Brian Christopher Raudenbush, Christopher Ronald Sarko
  • Publication number: 20130203803
    Abstract: Disclosed are CCR1 inhibitor compounds of the formula (I): which are useful in the treatment of autoimmune and other diseases. Also disclosed a pharmaceutical compositions containing the same, and methods of making and using same.
    Type: Application
    Filed: April 26, 2011
    Publication date: August 8, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventor: John D. Huber
  • Publication number: 20130065918
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A and B are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: March 8, 2012
    Publication date: March 14, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Jehrod Burnett Brenneman, John D. Huber, Brian Christopher Raudenbush, Christopher Ronald Sarko
  • Publication number: 20120295896
    Abstract: The present invention relates to compounds of formula (I) and (IA): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: September 20, 2011
    Publication date: November 22, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, John D. HUBER, Weimin W. LIU, Pui Leng LOKE, Tina Marie MORWICK, Alan OLAGUE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
  • Publication number: 20120245162
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein.
    Type: Application
    Filed: September 20, 2011
    Publication date: September 27, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
  • Publication number: 20120220561
    Abstract: The present invention relates to compound of formula (I): or pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: August 12, 2011
    Publication date: August 30, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, John D. HUBER, Ho Yin LO, Pui Leng LOKE, Weimin LIU, Tina Marie MORWICK, Alan OLAGUE, Doris RIETHER, Heather TYE, Lifen WU, Renee M. ZINDELL
  • Publication number: 20120214787
    Abstract: The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R5 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.
    Type: Application
    Filed: August 23, 2011
    Publication date: August 23, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Alessandra BARTOLOZZI, Todd BOSANAC, Zhidong CHEN, Stephane DE LOMBAERT, Jonathon Alan DINES, John D. HUBER, Weimin LIU, Ho Yin LO, Pui Leng LOKE, Tina Marie MORWICK, Peter Allen NEMOTO, Alan OLAGUE, Doris RIETHER, Heather Tye, Lifen WU, Renee M. ZINDELL
  • Publication number: 20110131655
    Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).
    Type: Application
    Filed: November 30, 2010
    Publication date: June 2, 2011
    Applicant: Cisco Technology, Inc.
    Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi
  • Patent number: 7873833
    Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: January 18, 2011
    Assignee: Cisco Technology, Inc.
    Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi
  • Publication number: 20080022106
    Abstract: A scalable method and apparatus that detects frequent and dispersed invariants is disclosed. More particularly, the application discloses a system that can simultaneously track frequency rates and dispersion criteria of unknown invariants. In other words, the application discloses an invariant detection system implemented in hardware (and/or software) that allows detection of invariants (e.g., byte sequences) that are highly prevalent (e.g., repeating with a high frequency) and dispersed (e.g., originating from many sources and destined to many destinations).
    Type: Application
    Filed: June 29, 2006
    Publication date: January 24, 2008
    Applicant: CiSCO TECHNOLOGY, INC.
    Inventors: Sumeet Singh, John D. Huber, Flavio Bonomi