Patents by Inventor John E. Landers

John E. Landers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of detecting amyotrophic lateral sclerosis (ALS)
    Patent number: 8753818
    Abstract: In one aspect, the invention is directed to a method of identifying an individual that has amyotrophic lateral sclerosis (ALS) or is at risk of developing ALS comprising detecting one or more alterations in a profilin 1 (PFN1) sequence of an individual in need thereof compared to a wild type profilin sequence. In another aspect, the invention is directed to a method of identifying an individual that has amyotrophic lateral sclerosis (ALS) or is at risk of developing ALS comprising selectively sequencing a profilin 1 (PFN1) sequence of an individual in need thereof; and detecting one or more alterations in the PFN1 sequence of the individual. If the one or more alterations are detected then the individual has ALS.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 17, 2014
    Assignee: The University of Massachusetts
    Inventors: John E. Landers, Robert H. Brown
  • Methods of Detecting Amyotrophic Lateral Sclerosis (ALS)
    Publication number: 20140148445
    Abstract: In one aspect, the invention is directed to a method of identifying an individual that has amyotrophic lateral sclerosis (ALS) or is at risk of developing ALS comprising detecting one or more alterations in a profilin 1 (PFN1) sequence of an individual in need thereof compared to a wild type profilin sequence. In another aspect, the invention is directed to a method of identifying an individual that has amyotrophic lateral sclerosis (ALS) or is at risk of developing ALS comprising selectively sequencing a profilin 1 (PFN1) sequence of an individual in need thereof; and detecting one or more alterations in the PFN1 sequence of the individual. If the one or more alterations are detected then the individual has ALS.
    Type: Application
    Filed: March 15, 2013
    Publication date: May 29, 2014
    Applicant: THE UNIVERSITY OF MASSACHUSETTS
    Inventors: John E. Landers, Robert H. Brown
  • High throughput methods for haplotyping
    Patent number: 6844154
    Abstract: The invention relates to high throughput methods for determining haplotypes. The high throughput methods are based on hybridization, fluorescence detection, primer extension, MALDI TOF, and HPLC.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: January 18, 2005
    Assignee: PolyGenyx, Inc.
    Inventor: John E. Landers
  • High throughput methods for haplotyping
    Publication number: 20030096231
    Abstract: The invention relates to high throughput methods for determining haplotypes. The high throughput methods are based on hybridization, fluorescence detection, primer extension, MALDI TOF, and HPLC.
    Type: Application
    Filed: March 30, 2001
    Publication date: May 22, 2003
    Inventor: John E. Landers