Patents by Inventor John Efcavitch

John Efcavitch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240093275
    Abstract: The invention provides methods and compositions to enhance the efficiency and sensitivity of molecular inversion probe (MIP) reactions. Probes include elements that allow MIP ends to abut for ligation while avoiding the possibility of polymerase strand displacement errors. Elements facilitate multiplexed detections, including MIP reaction product detections employing next generation sequencing (NGS) techniques.
    Type: Application
    Filed: September 8, 2023
    Publication date: March 21, 2024
    Inventors: Michael H. SHAPERO, Lawrence GREENFIELD, Ronald J. SAPOLSKY, Keith JONES, Laurent BELLON, Robert J. LIPSHUTZ, August ESTABROOK, John EFCAVITCH
  • Publication number: 20150284786
    Abstract: The invention provides methods and compositions to enhance the efficiency and sensitivity of molecular inversion probe (MIP) reactions. Probes include elements that allow MIP ends to abut for ligation while avoiding the possibility of polymerase strand displacement errors. Elements facilitate multiplexed detections, including MIP reaction product detections employing next generation sequencing (NGS) techniques.
    Type: Application
    Filed: April 3, 2015
    Publication date: October 8, 2015
    Inventors: Michael H. Shapero, Lawrence Greenfield, Ronald J. Sapolsky, Keith Jones, Laurent Bellon, Robert J. Lipshutz, August Estabrook, John Efcavitch