Patents by Inventor John Eid
John Eid has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220211780Abstract: Compositions and methods are provided for treating, mitigating, managing, reducing or preventing the onset of symptoms, signs or indicators of liver disorders as well as the disorders themselves. The compositions and methods include microbial compositions that are selected to improve gut function in the subjects to which they are administered, so as to bring about treatment of liver disorders and/or the signs, symptoms and indicators of those disorders.Type: ApplicationFiled: May 20, 2020Publication date: July 7, 2022Inventors: Orville Kolterman, Fanny Perraudeau, James Bullard, John Eid, Colleen Cutcliffe
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Publication number: 20220170091Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: November 5, 2021Publication date: June 2, 2022Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 11214830Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: October 21, 2019Date of Patent: January 4, 2022Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Publication number: 20200149100Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: October 21, 2019Publication date: May 14, 2020Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 10563255Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: June 23, 2017Date of Patent: February 18, 2020Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Publication number: 20170342481Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: June 23, 2017Publication date: November 30, 2017Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 9738929Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: December 19, 2016Date of Patent: August 22, 2017Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid, Cheryl Heiner, Kevin Travers
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Publication number: 20170121764Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: December 19, 2016Publication date: May 4, 2017Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 9556480Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: May 11, 2015Date of Patent: January 31, 2017Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Publication number: 20150307934Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: May 11, 2015Publication date: October 29, 2015Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 9057102Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: November 27, 2013Date of Patent: June 16, 2015Assignee: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 8906831Abstract: Methods for non-random loading of single analyte molecules into array structures are provided. The methods allow for distribution of a population of target molecules into a plurality of size confined regions such as wells. Sizing moieties are linked to individual target molecules. The sizing moieties are of sufficient size, relative to the size-confined reaction or observation regions, such that only a selected number of sizing moieties will fit into the size confined regions. The confined regions and the sizing moieties or target molecules comprise a selected charge that allow for controlling the loading of the sizing moities.Type: GrantFiled: March 30, 2009Date of Patent: December 9, 2014Assignee: Pacific Biosciences of California, Inc.Inventors: John Eid, Stephen Turner, Ravi Dalal, Benjamin Flusberg, Jonas Korlach, Steven Lin, Adrian Fehr, Fred Christians, Robin Emig, Jeremy Gray, Robert Sebra, Lei Sun, Stephen Dudek
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Publication number: 20140134629Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: ApplicationFiled: November 27, 2013Publication date: May 15, 2014Applicant: Pacific Biosciences of California, Inc.Inventors: Stephen Turner, Jon Sorenson, Kenneth Mark Maxham, John Eid
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Patent number: 8465922Abstract: Methods and systems for monitoring reactions by observing signals deriving from those reactions, using signal processing that allows differentiation between signals that are otherwise optically overlapping by conventional detection methods. Centroid determination is used to identify signal sources that are presenting confounding overlapping signals due to their physical proximity, and/or to identify discrete signals from different reaction centers.Type: GrantFiled: August 24, 2011Date of Patent: June 18, 2013Assignee: Pacific Biosciences of California, Inc.Inventors: John Eid, Stephen Turner
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Patent number: 8415128Abstract: Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage mitigating agents within the reaction mixture and/or interrogating different observation regions of the reaction mixture for a period that is less than a photodamage threshold period.Type: GrantFiled: July 26, 2011Date of Patent: April 9, 2013Assignee: Pacific Biosciences of California, Inc.Inventors: John Eid, Devon Murphy, Geoffrey Otto, Stephen Turner
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Patent number: 8383369Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: September 16, 2009Date of Patent: February 26, 2013Assignee: Pacific Biosciences of California, Inc.Inventors: Kenneth Mark Maxham, Jon Sorenson, John Eid, Patrick Marks, Kevin Travers, Donald Gray, Robin Emig, Mark Chaisson, Benjamin Flusberg
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Patent number: 8304191Abstract: Sequencing methods that use an exonuclease that comprises template dependent nucleobase binding activity are provided. Related compositions and sequencing systems are also provided.Type: GrantFiled: April 28, 2011Date of Patent: November 6, 2012Assignee: Pacific Biosciences of California, Inc.Inventors: John Eid, Alex Dewinter
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Patent number: 8143030Abstract: Methods, devices, and systems for performing intermittent detection during analytical reactions are provided. Such methods facilitate collection of reaction data from disparate reaction times. Further, such methods are useful for reducing photo-induced damage of one or more reactants in an illuminated analytical reaction at a given reaction time. In preferred embodiments, the reaction mixture is subjected to at least one illuminated and non-illuminated period and allowed to proceed such that the time in which the reaction mixture is illuminated is less than a photo-induced damage threshold period.Type: GrantFiled: March 27, 2009Date of Patent: March 27, 2012Assignee: Pacific Biosciences of California, Inc.Inventors: Kenneth Mark Maxham, Jon Sorenson, John Eid, Patrick Marks, Kevin Travers
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Publication number: 20120052490Abstract: Methods and systems for monitoring reactions by observing signals deriving from those reactions, using signal processing that allows differentiation between signals that are otherwise optically overlapping by conventional detection methods. Centroid determination is used to identify signal sources that are presenting confounding overlapping signals due to their physical proximity, and/or to identify discrete signals from different reaction centers.Type: ApplicationFiled: August 24, 2011Publication date: March 1, 2012Applicant: Pacific Biosciences of California, Inc.Inventors: John Eid, Stephen Turner
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Publication number: 20120028250Abstract: Compositions, devices, systems and methods for reducing and/or preventing photodamage of one or more reactants in illuminated analytical reactions by one or more of incorporating photodamage mitigating agents within the reaction mixture and/or interrogating different observation regions of the reaction mixture for a period that is less than a photodamage threshold period.Type: ApplicationFiled: July 26, 2011Publication date: February 2, 2012Applicant: Pacific Biosciences of California, Inc.Inventors: John Eid, Devon Murphy, Geoffrey Otto, Stephen Turner