Patents by Inventor John Ernest Walker

John Ernest Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Over-expression of proteins
    Patent number: 6361966
    Abstract: The invention describes a method for selecting host cell mutants which are resistant to expression system toxicity, comprising the steps of growing an expression system comprising host cells transformed with an expression vector, inducing the expression system such that a toxic effect is observed, and selecting viable cells in which the expression vector continues to function. Cells thus obtained are useful for the expression of polypeptide gene products in microorganisms.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: March 26, 2002
    Assignee: Medical Research Council
    Inventors: John Ernest Walker, Bruno Miroux