Patents by Inventor John F. Leite

John F. Leite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isotopically-Labeled Proteome Standards
    Publication number: 20110262947
    Abstract: The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.
    Type: Application
    Filed: April 22, 2011
    Publication date: October 27, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: John F. Leite, Robert Marshall Pope, Mahbod Hajivandi, Xiquan Liang
  • COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY
    Publication number: 20110226942
    Abstract: The invention provides compositions, kits, and methods for calibrating a mass spectrometer using two or more recombinant proteins and one or more energy-absorbing molecules. The recombinant proteins of the invention display high purities, making them suitable for use in mass spectrometry.
    Type: Application
    Filed: January 18, 2011
    Publication date: September 22, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: MAHBOD R. HAJIVANDI, ROBERT M. POPE, MEHRNOOSH SADEGHI, XIQUAN LIANG, JOHN F. LEITE
  • Isotopically-labeled proteome standards
    Patent number: 7939331
    Abstract: The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: May 10, 2011
    Assignee: Life Technologies Corporation
    Inventors: John F. Leite, Robert Marshall Pope, Mahbod Hajivandi, Xiquan Liang