Abstract: In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Abstract: A detector for a test system having multiple indicators uses position sensitive light detection by multiple light detecting elements to produce a measured signal vector. The measured signal vector, which may include fewer components than there are indicators, has a magnitude and a direction that can identify how many and/or which set of the indicators are active. Analysis of the measured vector signal can use vector composition/decomposition techniques.

Abstract: An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location of the at least one position marker indicates a position of the region of interest. A diagnostic test system includes a reader that obtains light intensity measurement from exposed regions of the test strip, and a data analyzer that performs at least one of (a) identifying ones of the light intensity measurements obtained from the test region based on at least one measurement obtained from the at least one reference feature, and (b) generating a control signal modifying at least one operational parameter of the reader based on at least one measurement obtained from the at least one reference feature.

Abstract: In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspect, an assay test strip includes a test label that specifically binds a target analyte and at least one non-specific-binding label that is free of any specific binding affinity for the target analyte. Systems and methods of reading assay test strips also are described.

Abstract: A detector for a test system having multiple indicators uses position sensitive light detection by multiple light detecting elements to produce a measured signal vector. The measured signal vector, which may include fewer components than there are indicators, has a magnitude and a direction that can identify how many and/or which set of the indicators are active. Analysis of the measured vector signal can use vector composition/decomposition techniques.

Abstract: A diagnostic assay reader includes a detector configured to read a diagnostic assay result and develop a result signal that is indicative of the result, a processor configured to process the result signal, and an external power interface connected to the detector and to the processor, the external power interface configured to receive external power for the diagnostic assay reader.

Abstract: A solid state relay uses an optically controlled shunt and series enhancement circuit between a photodiode array and an output device to provide enhanced turn-off and transient immunity characteristics. A Faraday shield may be used to cover optically active components and to provide protection against false turn-on and turn-off caused by the transients.

Abstract: A solid state relay uses an optically controlled shunt and series enhancement circuit between a photodiode array and an output device to provide enhanced turn-off and transient immunity characteristics. A Faraday shield may be used to cover optically active components and to provide protection against false turn-on and turn-off caused by the transients.