Abstract: The invention relates to cushioned articles selected from items of footwear, cushioned seating, pillows, mattresses, beds, with air or gas pockets, inflatable air beds, orthopaedic support devices, orthotic insoles, soft robotic devices, safety headwear, safety body wear, body armour, crumple zones in vehicles, pneumatic deformable crash structures or barriers, and spring systems with multiple spring rates, which have improved compliance and shock absorbance characteristics. The cushioned articles include one or more cushioning elements which comprise pressurised gas contained within one or more primary pressurised gas storage chambers, wherein the bulk modulus, K, of the pressurised gas inside said pressurised chambers is <1. The pressurised gas in such cushioned articles is preferably in fluid communication with one or more gas adsorbent materials.

Abstract: A system, apparatus, and/or method is disclosed for—inter alia—producing a product. One or more financial characteristics relating to one or more sample products may be received. For each of the sample products, a value for each of one or more respective properties of the sample product may be received. The received values of the one or more respective properties of the sample products, the one or more received financial characteristics relating to the sample products, and a desired financial characteristic for a potential product may be input into the machine learning model. A value for each of the one or more respective properties for the potential product may be determined based on the desired financial characteristic for the potential product. A product having the determined value for each of the one or more respective properties for the potential product may be produced.

Abstract: A video wall and system is disclosed having a computer with a memory or access to a public or private cloud containing a video file and a processor for executing the video file and a plurality of light emitting diode (LED) tiles interconnected to one another and to the computer via wired or wireless transmission, each of the plurality of LED tiles configured to work together to display a video content generated from the video file that extends across all of the plurality of LED tiles. Upon user interaction or detection of a user, one or more of the plurality of LED tiles seamlessly transitions away from the video content to display a separate video content for interaction with the user.

Abstract: According to one aspect, a method includes obtaining a command on a vehicle, the command being arranged to identify a first action to be taken by the vehicle, wherein the vehicle is in a first vehicle state and the command has a first command state. The method also includes determining, on the vehicle, whether the first command state is consistent with the first vehicle state. When it is determined that the first command state is consistent with the first vehicle state, the method includes executing the first command. When it is determined that the first command state is not consistent with the first vehicle state, the method includes identifying the first command as an illegitimate command and ignoring the illegitimate command.

Abstract: An automated documents management system may be configured to: enable an applicant user, such as a seafarer, to create, store, and access personal, career, and professional development information in the system database so that the applicant user can see all his documents and applications with their statuses in online format; enable an applicant user, such as a seafarer, to take online tests or examinations, via one or more client devices, instead of having to going offline and travel to special testing centers in order to earn a license, professional certification, or other credential that verifies someone's knowledge, skills and abilities to perform a specific job; and generate electronic documents, such as a license, professional certification, or other credential that verifies someone's knowledge, skills and abilities to perform a specific job which can then be verified in any point of the world if via an internet network connection.

Abstract: An injection-molded ski includes a ski body and two ski edges attached to opposite edge surfaces of the ski body. The ski body is formed from a uniform material and has top, bottom, and edge surfaces and a binding mounting platform. The binding mounting platform is formed on the top surface and receives a boot binding. The ski edges comprise an edge portion and securing features. In one embodiment, a ski is injection-molded using a molding material, such as glass-reinforced nylon or a combination of one or more suitable materials. A novel mold facilitates injection of molding material around and/or between the securing features thereby locking the edges in place when the molding material cools. Compared to conventional skis, the novel injection-molded ski has improved durability, flexibility, strength, and performance characteristics, reduced manufacturing complexity that avoids typical layup processes, and reduced susceptibility to failure due to moisture or wear.

Abstract: The present invention relates to a method and apparatus for providing and/or receiving audible sound. In particular, the invention relates to apparatus, such as a micro speaker, which includes an active region which comprises an adsorbent element in the form of a self-supporting monolith-like element with a porous reticulated structure. The adsorbent element includes adsorbent material which comprises microporous organic polymer (MOP) material. The apparatus of the present invention is suitable for use in an electronic device, for example a mobile or portable electronic device, to provide improved audible sound.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.

Abstract: The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.

Abstract: The present invention relates to a method and apparatus for providing and/or receiving audible sound. In particular, the invention relates to apparatus, such as a micro speaker, which includes an active region which comprises an adsorbent element in the form of a self-supporting monolith-like element with a porous reticulated structure. The adsorbent element includes adsorbent material which comprises microporous organic polymer (MOP) material. The apparatus of the present invention is suitable for use in an electronic device, for example a mobile or portable electronic device, to provide improved audible sound.

Abstract: The invention relates to a hydropneumatic suspension component such as a gas charged damper. The invention further relates to a floating piston for a hydropneumatic suspension component. Uses of adsorbent material and/or open-cell foam are also disclosed.

Abstract: The present invention provides processes of synthesis and purification of a bromodomain inhibitor, Compound 1, which compound includes crystalline forms, amorphous forms, solvates, and hydrates thereof. Embodiments of the disclosure relate to chemical synthesis routes of Compound 1 that provide a scalable method that results in highly pure final product. A further embodiment relates to methods to isolate the most stable polymorph of Compound 1 by crystallization from formic acid and water.

Abstract: A portable ion mobility spectrometry apparatus (1) for detecting an aerosol and a method for using the apparatus. The apparatus comprises an ion mobility spectrometer (3); a portable power source (5) carried by the apparatus for providing power to the apparatus (1); an inlet (7) for collecting a flow of air to be tested by the spectrometer (3); a heater (4) configured to heat the air to be tested to vapourise an aerosol carried by the air and a controller (2) configured to control the spectrometer (3) to obtain samples from the heated air, wherein the controller is configured to increase a heat output from the heater (4) for a selected time period before obtaining samples from the heated air.

Abstract: A digital transaction ledger with a DNA-related parameter is provided by obtaining DNA-based data unique to a particular entity, and establishing a DNA-related ledger parameter using the DNA-based data. Further, the method includes associating the DNA-based ledger parameter with a digital transaction ledger, making the digital transaction ledger related, at least in part, to the obtained DNA-based data.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R, R1B, R1C, R2B, R2C, B1, W, X, Y, Z are defined herein.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.

Abstract: Techniques for vector-based identification of software dependency relationships are described herein. An aspect includes determining a first dependency relationship value between a first code segment and a second code segment. Another aspect includes calculating a magnitude vector based on the first dependency relationship value and a second dependency relationship value corresponding to the first code segment and the second code segment. Another aspect includes determining a relationship score for the first code segment and the second code segment based on the magnitude vector and the first dependency relationship value.

Abstract: Techniques for vector-based identification of software dependency relationships are described herein. An aspect includes determining a first dependency relationship value between a first code segment and a second code segment. Another aspect includes calculating a magnitude vector based on the first dependency relationship value and a second dependency relationship value corresponding to the first code segment and the second code segment.

Abstract: A submersible pen system (100) for aquaculture is described. The pen comprises a hub (4) for coupling the pen system (100) to an anchor and a collar (1) circumferentially arranged around the hub (4) and having a variable buoyancy. A first end of at least one net panel (6) is coupled to the collar (1) and at least one tensioning element (5) is coupled to a second end of the at least one net panel (6). A stabilising diaphragm (50) is coupled to each of the hub (4) and the collar (1) and is at least partially deformable, the at least one net panel (6) providing surfaces at least partially defining a pen having a containment volume. The stabilising diaphragm (50) is configured to operatively provide a stabilising force between the hub (4) and the collar (1) such that a deformation of the stabilising resilient diaphragm (50) effects a degree of movement in the collar (1) with respect to the hub (4) when exposed to external dynamic loading.

Abstract: A scaled process of preparing maytansinol, FORMULA II, is provided by reacting a compound of Formula I, wherein R is selected from the group consisting essentially of alkyl, branched alkyl, aryl, alkenyl, alkynyl, as well as substituted variations thereof, with at least one organometallic reagent to produce the compound of Formula II; and, isolating the compound of Formula II.