Patents by Inventor John Frenz

John Frenz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purified forms of DNase
    Patent number: 6932965
    Abstract: The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: August 23, 2005
    Assignee: Genentech, Inc.
    Inventors: John Frenz, Steven J. Shire, Mary B. Sliwkowski
  • Purified forms of DNase
    Publication number: 20030077267
    Abstract: The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
    Type: Application
    Filed: May 22, 2002
    Publication date: April 24, 2003
    Applicant: Genentech, Inc.
    Inventors: John Frenz, Steven J. Shire, Mary B. Sliwkowski
  • Purified forms of DNase
    Patent number: 6440412
    Abstract: The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
    Type: Grant
    Filed: August 11, 2000
    Date of Patent: August 27, 2002
    Assignee: Genentech, Inc.
    Inventors: John Frenz, Steven J. Shire, Mary B. Sliwkowski
  • Purified forms of DNase
    Patent number: 5783433
    Abstract: The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 21, 1998
    Assignee: Genentech, Inc.
    Inventors: John Frenz, Mary B. Sliwkowski
  • Purified forms of DNASE
    Patent number: 5279823
    Abstract: The present invention provides the identification and characterization of two components of a recombinant preparation of DNase. These components are the purified deamidated and non-deamidated human DNases. Taught herein are the separation of these components and the use of the non-deamidated species as a pharmaceutical per se, and in particular in compositions wherein the species is disclosed within a plastic vial, for use in administering to patients suffering from pulmonary distress.
    Type: Grant
    Filed: June 8, 1992
    Date of Patent: January 18, 1994
    Assignee: Genentech, Inc.
    Inventors: John Frenz, Steven J. Shire, Mary B. Sliwkowski