Abstract: The present specification discloses pharmaceutical composition disclosed herein comprises one or more therapeutic compounds, one or more glycerolipids, and one or more digestion enhancers. The disclosed glycerolipids comprise one or more hard fats and one or more liquid fats. The disclosed digestion enhancers comprise one or more bile acids, one or more phospholipids, one or more free C14-24 fatty acids, one or more free C14-24 fatty acid surfactants, or any combination thereof. The present specification also discloses methods and procedures to formulate the disclosed one or more therapeutic compounds into the disclosed pharmaceutical compositions.

Abstract: A method and system for generating synthetic images for use in a database is described. The database is used for delineation of features in real images, the method comprising the steps of: providing a delineated image acquired using a first scanner, defining a model related to the generation of synthetic images using a second scanner, processing the delineated image using the model to generate a synthetic image, mapping contours to the synthetic image to form a synthetic image-contour pair; repeating providing, defining and processing steps to generate a plurality of synthetic images and contour pairs for the database; using said database of synthetic images and contour pairs to optimise a contouring algorithm, where the optimised algorithm generates contours for the real images of the same type as the synthetic images; processing one or more further real images to contour and delineate features on the further real image using the algorithm.

Abstract: A method (900) of generating an atlas for a universal atlas database (901) is provided. A new medical scan image (905) is provided. A universal auto-contouring operation (920) is performed on the medical scan image, to generate a set of universal contours (930) for the medical scan image. A local auto-contouring customisation operation (940) is performed on the medical scan image, to generate a set of local contours (950) for the medical scan image. The set of local contours is standardised (980) using a trained model to compensate for biases in the set of local contours, thereby creating a set of standardised global contours (985) for the medical scan image. The set of standardised global contours (985) and the medical scan image (905) can be added to the universal atlas database (901) as a new atlas, thereby expanding the set of atlases that are available in the universal atlas database.

Abstract: A method and system for generating synthetic images for use in a database is described. The database is used for delineation of features in real images, the method comprising the steps of: providing a delineated image acquired using a first scanner, defining a model related to the generation of synthetic images using a second scanner, processing the delineated image using the model to generate a synthetic image, mapping contours to the synthetic image to form a synthetic image-contour pair; repeating providing, defining and processing steps to generate a plurality of synthetic images and contour pairs for the database; using said database of synthetic images and contour pairs to optimise a contouring algorithm, where the optimised algorithm generates contours for the real images of the same type as the synthetic images; processing one or more further real images to contour and delineate features on the further real image using the algorithm.

Abstract: A method (900) of generating an atlas for a universal atlas database (901) is provided. A new medical scan image (905) is provided. A universal auto-contouring operation (920) is performed on the medical scan image, to generate a set of universal contours (930) for the medical scan image. A local auto-contouring customisation operation (940) is performed on the medical scan image, to generate a set of local contours (950) for the medical scan image. The set of local contours is standardised (980) using a trained model to compensate for biases in the set of local contours, thereby creating a set of standardised global contours (985) for the medical scan image. The set of standardised global contours (985) and the medical scan image (905) can be added to the universal atlas database (901) as a new atlas, thereby expanding the set of atlases that are available in the universal atlas database.

Abstract: Methods and systems for digital rights management are disclosed. Exemplary embodiments of the invention provide a system and method that allows the author of a design file to encrypt the file's contents, so that only authorized users can view the file, and that allows the author to identify specific users for authorization. The author selects the users that are allowed to open the encrypted file. Selected users are called “recipients”. The author then designates the rights granted to the recipients. Preferably, the author identifies users and users are authenticated by means of the user's digital certificates. The author may also have the ability to specify what operations a given user can perform, including view, print/plot, export, copy to clipboard, access history, and edit. An author can also digitally sign a document or file using their digital certificate. A hash value is created for the item to be signed.

Abstract: Conventional file-based engineering design data for an engineering model are represented by a plurality of components. The plurality of components are kept in stores, which reside on servers. Each store contains the components that correspond to the elements of one design file. The stores also maintain a history of changes made to the components. A plurality of client computers are bidirectionally connected to the servers. Each client computer may obtain the current version of the components and may send locally edited versions of the components back to the servers to replace the current versions in the stores. At the client computer, the user interacts with the components using conventional file-based software.

Abstract: Methods and systems for digital rights management are disclosed. Exemplary embodiments of the invention provide a system and method that allows the author of a design file to encrypt the file's contents, so that only authorized users can view the file, and that allows the author to identify specific users for authorization. The author selects the users that are allowed to open the encrypted file. Selected users are called “recipients”. The author then designates the rights granted to the recipients. Preferably, the author identifies users and users are authenticated by means of the user's digital certificates. The author may also have the ability to specify what operations a given user can perform, including view, print/plot, export, copy to clipboard, access history, and edit. An author can also digitally sign a document or file using their digital certificate. A hash value is created for the item to be signed.

Abstract: A computer system for modeling is disclosed, where the computer system has a storage device, first and second platforms, a portable persistent model, and first and second platform-dependent computerized modeling systems (CMS). Each platform is interfaced to the storage device and provides system-dependent services. The first platform has a first type of operating system and a first type of computer hardware including a first memory, and the second platform has a second type of operating system and a second type of computer hardware including a second memory. The model resides in the storage device in a platform-independent format and includes persistent component objects. The first CMS resides in the first platform memory and the second platform-dependent CMS resides in the second platform memory.

Abstract: A computer system for modeling is disclosed, where the computer system has a storage device, first and second platforms, a portable persistent model, and first and second platform-dependent computerized modeling systems (CMS). Each platform is interfaced to the storage device and provides system-dependent services. The first platform has a first type of operating system and a first type of computer hardware including a first memory, and the second platform has a second type of operating system and a second type of computer hardware including a second memory. The model resides in the storage device in a platform-independent format and includes persistent component objects. The first CMS resides in the first platform memory and the second platform-dependent CMS resides in the second platform memory.

Abstract: A computer system for modeling is disclosed, where the computer system has a storage device, first and second platforms, a portable persistent model, and first and second platform-dependent computerized modeling systems (CMS). Each platform is interfaced to the storage device and provides system-dependent services. The first platform has a first type of operating system and a first type of computer hardware including a first memory, and the second platform has a second type of operating system and a second type of computer hardware including a second memory. The model resides in the storage device in a platform-independent format and includes persistent component objects. The first CMS resides in the first platform memory and the second platform-dependent CMS resides in the second platform memory.

Abstract: A close-spaced diode array in which connection to driver circuitry is enabled by application of a flip-chip solder bonding technique. Not only does this allow dense packing, high pixel content to be achieved but has concomitant advantages of increased light efficiency and improved heat sinking.