Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: A blade having an attachment portion including an aperture defining an anchor center, the attachment portion configured to couple with an oscillating power tool. The blade also has a first blade portion having a first cutting edge, and a second blade portion having a second cutting edge. The first and second blade portions are generally coplanar and extend away from the attachment portion in an outward direction. The first cutting edge has a first horizontal linear dimension measured perpendicular to the outward direction, the first horizontal linear dimension being 3.5 to 4.0 inches to generally correspond with a first dimension of a single outlet gang box. The second cutting edge has a second horizontal linear dimension measured perpendicular to the outward direction, the second horizontal linear dimension being 2.1 to 2.6 inches to generally correspond with a second dimension of the single outlet gang box.

Abstract: A dishwasher has a tub at least partially defining a treating chamber for receiving dishes for treatment according to an automatic cycle of operation. At least one wall of the tub has spaced outer and inner panels and a conduit framework extending between the outer and inner panels to define a plurality of conduits. The conduits can convey liquid, air, and/or electrical wiring.

Abstract: A dishwasher has a tub at least partially defining a treating chamber for receiving dishes for treatment according to an automatic cycle of operation. At least one wall of the tub has spaced outer and inner panels and a conduit framework extending between the outer and inner panels to define a plurality of conduits. The conduits can convey liquid, air, and/or electrical wiring.

Abstract: A switchable valve train member, such as a deactivating valve lash adjuster or a deactivating hydraulic valve lifter, including a pin housing slidably disposed within an axial bore in a body. A transverse bore in the pin housing contains a retractable locking pin that engages a feature in the body including a locking surface whereby the body and the pin housing are locked together for mutual actuation by rotation of a cam lobe. A lash ring at the outer end of the body includes a portion extending into the axial bore that limits the travel of the pin housing within the body and thereby sets the internal mechanical lash in the switchable member. The axial thickness of the lash ring may be varied between assemblies to compensate for manufacturing variation in the components and is secured to the body in any of various configurations.

Abstract: A switchable valve train member, such as a deactivating valve lash adjuster or a deactivating hydraulic valve lifter, including a pin housing slidably disposed within an axial bore in a body. A transverse bore in the pin housing contains a retractable locking pin that engages a feature in the body including a locking surface whereby the body and the pin housing are locked together for mutual actuation by rotation of a cam lobe. A lash ring at the outer end of the body includes a portion extending into the axial bore that limits the travel of the pin housing within the body and thereby sets the internal mechanical lash in the switchable member. The axial thickness of the lash ring may be varied between assemblies to compensate for manufacturing variation in the components and is secured to the body in any of various configurations.

Abstract: A method of and an apparatus for performing efficient software emulation of a multi-processor target computer by a host computer. The software technique permits multiple processors to be emulated by a single processor. The use of software emulation permits the host computer to execute both host programs and target programs. The software emulation is made particularly efficient by utilizing the operation code combined with a separate four bit field to directly address the corresponding host instructions.

Abstract: Flame retardant textile structures which may be used alone or in combination with one or more covering layer to impart enhanced flame resistance in a wide array of applications. In particular, the textile structure incorporates a wool-based felt which contains about 60% by weight or greater of a mammal generated wool material.

Abstract: A bearing for supporting the drum of a clothes dryer which includes an interior structural layer of high coherency felted fibrous material and an exterior surface covering for contact with the dryer drum formed of fibrous material including a wool constituent. The felted interior provides support and noise damping character while the exterior surface covering provides friction reduction and enhanced flame retardancy.

Abstract: A retainer clip includes a U-shaped body, first and second legs, and a resilient segment interconnecting first ends of the legs. The legs are adapted to resiliently engage opposite sides of a wall of a rockable actuator member. A second end of the first leg includes a guide recess having a clip edge. A second end of the second leg includes a gripping recess and opposing resilient edges adapted to frictionally grip opposite sides of a cylindrical member engaged with a socket in a second side of the wall. The resilient edges frictionally grip the cylindrical member at points on an axis intersecting and normal to the axial center line of the cylindrical member. The retainer clip is adapted to frictionally retain the cylindrical member in the socket to thereby form a subassembly for installation in a valve train.

Abstract: A valve actuator subassembly, such as a finger follower and a hydraulic lash adjuster (HLA) are held together for shipping and installation in an engine valve train by a retainer clip made of wire or sheet metal or plastic material. The retainer clip has generally a U-shaped body with legs that clip over the end of a wall in the body of the finger follower. A first leg includes a gripping recess that engages diametrically opposite sides of a cylindrical member, such as the plunger of a HLA. A second leg of the clip includes a guide recess that engages a portion on a first side of the wall at a point offset from the axial centerline of the HLA and closer to the point at which the finger follower contacts the valve stem. The gripping recess includes opposed resilient edges that frictionally engage the cylindrical surface of, for example, the HLA plunger and holds it in assembly with the finger follower.