Abstract: A water soluble preservative admixture of biocidal compounds for addition to commercial use compositions at predetermined use levels, and uniformly distributed therein, to provide long-time synergistic biocidal activity against a wide range of fungi and both gram-negative and gram-positive bacteria, which comprises powders of(a) one or more methylol compounds, or their equivalents, and(b) iodopropynyl alcohol, or its ester, carbamate or ether derivative thereof, in a weight ratio of (a):(b) of 100:1 to 2000:1.

Abstract: A water soluble, antimicrobial composition having antifungal activity useful for disinfecting a contact lens comprise (a) polyhexamethylene biguanide and (b) iodopropynylbutyl carbamate, in a weight ratio of (a):(b) of at least 100:1.

Abstract: A water soluble preservative admixture of biocidal compounds for addition to commercial use compositions at predetermined use levels, and uniformly distributed therein, to provide long-time synergistic biocidal activity against a wide range of fungi and both gram-negative and gram-positive bacteria, which comprises powders of(a) one or more methylol compounds, or their equivalents, and(b) iodopropynyl alcohol, or its ester, carbamate or ether derivative thereof,in a weight ratio of (a):(b) of 100:1 to 2000:1.

Abstract: What is provided herein are active antimicrobial polymeric quaternary ammonium compounds which are capped with defined C.sub.12 /C.sub.14 alkyl groups optionally coprecipitated with polyvinylpyrrolidone (PVP). The compounds of the invention have the formula: ##STR1## where n is at least 2, e.g. 2-30, and C.sub.12 /C.sub.14 alkyl preferably is 50:50 wt. % of dodecyl/tetradecyl alkyl.

Abstract: A free-flowing, fine white powder of a substantially aqueous stable complex of a strongly swellable, moderately crosslinked polyvinylpyrrolidone (PVP) having an aqueous gel volume of about 15 to 150 ml/g of PVP and a Brookfield viscosity in 5% aqueous solution of at least about 10,000 cps, and H.sub.2 O.sub.2, in substantially a 1:1 molar ratio of said constituents.

Abstract: PVP-HI-I.sub.2 complexes having a partition coefficient above 300 were prepared by oxidizing a PVP-HI intermediate in air and light at room temperature. These complex products were light in color, water soluble and stable.

Abstract: What is described herein is a PVP-I.sub.2 composition comprising strongly swellable, lightly crosslinked PVP complex to iodine, wherein said composition is capable of releasing free iodine slowly with time in the presence of water. Preferably the complex has about 10-15% by weight available iodine and about 4-8 weight % iodide, and is a free-flowing, fine, lightly yellow powder.

Abstract: An antimicrobial, low toxicity, non-irritating composition comprises a blend of several bis-quaternary ammonium compounds coprecipitated with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer.

Abstract: An antimicrobial, low toxicity blend composition of several bis-quaternary ammonium compounds of defined structure, and in defined amounts of the composition, and polyvinylpyrrolidone, is described herein.

Abstract: This invention relates to an antifungal block copolymer of poly(vinyl lactam) having the formula ##STR1## where m has a value of from 1 to 3 and from about 15 to about 25 wt. % of a quaternized amino alkyl acrylamide comonomer wherein the quaternizing anion is in part halide --O--CO(CH.sub.2).sub.s CH.dbd.CHZ wherein s has a value of from 4 to 14 and Z is hydrogen or a C.sub.1 to C.sub.4 alkyl radical, which copolymer is comprised of the following units ##STR2## wherein m has a value of from 1 to 3; p has a value of from 1 to 5; r has a value of from 2 to 6; each of X and Y is hydrogen or a C.sub.1 to C.sub.4 alkyl and each of R.sub.1, R.sub.2 and R.sub.3 is C.sub.1 to C.sub.4 alkyl. The invention also relates to the use of the above polymers as antifungal agents.

Abstract: Urea-hydrogen peroxide-polyvinylpyrrolidone (PVP) in the form of a free-flowing powder is stable against decomposition in water and alcohol solvents. The product is obtained by spraying an aqueous solution of urea-hydrogen peroxide onto a fluidized bed of PVP and drying; it contains about 5%-20% by weight H.sub.2 O.sub.2 and less than about 5% water. The urea-hydrogen peroxide solution is applied onto the fluidized PVP bed at a predetermined rate, suitably about 0.5-30 g of solution/minute/kg PVP in the bed, and, preferably, about 1-3 g/min/kg PVP.

Abstract: An antimicrobial, low toxicity blend composition of several bis-quaternary ammonium compounds of defined structure, and in defined amounts of the composition, is described herein.

Abstract: Copolymers of vinyl pyrrolidone and a quaternary ammonium monomer complexed with H.sub.2 O.sub.2 in the form of free-flowing powders is described. The products are made in a fluidized bed of said copolymer maintained at a reaction temperature of from room temperature to about 60.degree. C. The fluidized bed is contacted with finely divided droplets of a 30 to 85% by weight aqueous H.sub.2 O.sub.2 solution at a feed rate of about 1-10 g/minute/kg copolymer present. The copolymer-H.sub.2 O.sub.2 product preferably contains about 10-20% H.sub.2 O.sub.2 (1:1 molar ratio), and less than about 5% water. The product can be used as a hair bleach enhancer which provides dual hair conditioning properties.

Abstract: A toothpaste composition is provided which includes the strontium salt of maleic anhydride-methyl vinyl ether copolymer. This ingredient is capable of desensitizing the nerve endings of a tooth in saliva or water because of an extension of the contact time of the strontium on the tooth surface.

Abstract: Urea-hydrogen peroxide-polyvinylpyrrolidone (PVP) in the form of a free-flowing powder is stable against decomposition in water and alcohol solvents. The product is obtained by spraying an aqueous solution of urea-hydrogen peroxide onto a fluidized bed of PVP and drying; it contains about 5%-20% by weight H.sub.2 O.sub.2 and less than about 5% water. The urea-hydrogen peroxide solution is applied onto the fluidized PVP bed at a predetermined rate, suitably about 0.5-30 g of solution/minute/kg PVP in the bed, and, preferably, about 1-3 g/min/kg PVP.

Abstract: A free-standing, porous foam product comprising an integral network of PVP molecules hydrogen-bonded to H.sub.2 O.sub.2 molecules, optionally including a water-soluble gelling agent; e.g. hydroxyethyl cellulose; in an amount up to 60% by weight of the product, its PVP content being about 25-90% by weight of the product, and the H.sub.2 O.sub.2 content being about 5-24% by weight. In the absence of a gelling agent, the product has a bulk density of about 0.3 to about 0.5 g/cc and a porosity of about 60-70%. When a gelling agent is present in the product, its bulk density and porosity of the product is substantially reduced and, accordingly, it has a more foam-like structure and appearance.

Abstract: A process is described for carrying out aqueous and non-aqueous polymerization of polymerizable monomers, particularly vinyl monomers, and, preferably, vinylpyrrolidone, in the presence of a mixture of a stable, high purity, free-flowing, fine white powder of a substantially anhydrous 1:1 molar ratio complex of polyvinylpyrrolidone-hydrogen peroxide (PVP--H.sub.2 O.sub.2), respectively, and a transition metallic ion, as a free radical initiator, is described herein. Preferred polymerizations are the homopolymerization of vinylpyrrolidone and the copolymerization of maleic anhydride and a C.sub.1 -C.sub.5 alkyl vinyl ether.

Abstract: A method of preparing a stable, low K-value, water-soluble polyvinylpyrrolidone-iodine product in the form of a uniform, free-flowing powder which comprises mixing a given amount of water-soluble polyvinylpyrrolidone polymer having a K-value of about 10-20 and about 10-20% by wt. iodine, and about 0.1-0.5% isopropanol, intimately mixing the reactants at room temperature for a sufficient period of time for the iodine to disappear as a separate phase, and then heating the reaction powders while mixing at about 65.degree.-85.degree. C. for a reaction period of at least about 18 hours.

Abstract: A process for preparing a water-insoluble PVP-iodine product which comprises intimately mixing water-insoluble PVP, about 10 to 20% by weight of iodine powder and about 0.05 to 1% by weight of isopropanol, heating the reaction mixture at a mixing temperature of about 30.degree.-60.degree. C. for about 0.5 to 6 hours, and heating the mixture at a reaction temperature of about 75.degree. to 98.degree. C. for about 10-24 hours, thereupon forming a stable, uniform, free-flowing powder having an available iodine content of about 9-13% and an iodide content of about 4-6%.

Abstract: What is provided herein is a stabilized, aqueous, film-forming, antimicrobial composition of hydrogen peroxide. The active, oxygen-generating hydrogen peroxide component in the composition is stabilized in an aqueous-polyol solvent system of predetermined polarity containing PVP. In contrast, similar formulations without PVP experienced a loss of peroxide activity upon standing. Suitably, the composition herein includes about 1-20% by weight hydrogen peroxide, about 0.1-50% by weight PVP, and about 0.1-80% by weight of a polyol, the rest being water. Preferably, about 5-20% by weight of water is present in the composition. Additional solvents may be included therein, such as alcohols, ether oxides, esters, triglycerides of fatty acids, hydrocarbons, N-vinyl lactams, silicone oils, and polyether oligomers.