Abstract: A compartmentalized refrigeration case for cans of beverage and/or food with a handle and straps for portability by hand or over the shoulders. The refrigeration compartments in the interior of the case are formed by at least one horizontal layer of thermoplastic coated, removable, reusable, cooling units shaped to surround standard size beverage cans. The compartments are enclosed by multi-layer panels comprised of a thermally insulating and supportive foam sandwiched between an inner lining of waterproof material and an outer covering of water-resistant, durable fabric. Each refrigeration compartment is accessible through the front panel of the case by an insulated, door with a fastener such as VELCRO adjacent each compartment. This results in a convenient and versatile case, since every can in the case is accessible through one of the doors at all times.