Abstract: The subject invention relates to a novel system for rapid, venous infusion of a physiologic fluid, such as blood, into a patient, comprising in combination a reservoir for the physiologic fluid having an inlet port for receiving the physiologic fluid and an outlet port for dispensing the physiologic fluid, an infusion pump to propel the physiologic fluid through the system, a heating/cooling unit to control the temperature of the physiologic fluid, a sensor to monitor the pressure of the physiologic fluid, one or move cannula for infusing the physiologic fluid into the venous system of the patient, and flexible conduits connecting the components of the system to the physiologic fluid to and from each of the components of the system.