Abstract: A ranging system includes a drill string comprising a bottom hole assembly (BHA). A plurality of ranging devices are positioned in a spaced-apart orientation on the drill string and are operable to provide a conducting contact with a formation. At least one insulator member is positioned on the drill string between the plurality of ranging devices and is operable to provide a non-conducting contact with the formation. During drilling operations, the plurality of ranging devices provide conducting contact with a formation while the at least one insulator member provides non-conducting contact with the formation so to enhancing ranging operations while drilling. A method of modeling and simulating drill string response is provided to identify locations along the drill string for positioning insulator members.

Abstract: A method of manufacturing a power unit for a downhole drilling motor includes fabricating a stator that provides two or more stator lobes that define an internal profile, and fabricating a rotor that provides at least one rotor lobe that defines an external profile that both rotates and precesses within the internal profile during operation. At least one of an external geometry and an internal geometry of the rotor along all or a portion of the rotor may be varied to alter a stiffness and mass of the rotor and thereby optimize stiffness and force balancing with respect to the stator. The rotor may then be rotatably positioned within the stator and thereby optimize the functioning and reliability of the motor power unit, of the downhole drilling motor assembly, of associated downhole drilling equipment, and to enhance directional drilling tendency modelling and directional drilling trajectory control.

Abstract: The invention provides derivatives and analogs of triazatetracyclo[7.7.0.01,13.02,7]-hexadeca-2,4,6,10,12-pentaenes, 5,7,11-triazatetracyclo[8.7.0.01,6.012,17]-heptadeca-6,8,12,14,16-pentaenes, pharmaceutical compositions comprising these compounds and methods for treatment of hepatitis C viral infections using these compounds.

Abstract: A ranging system includes a drill string comprising a bottom hole assembly (BHA). A plurality of ranging devices are positioned in a spaced-apart orientation on the drill string and are operable to provide a conducting contact with a formation. At least one insulator member is positioned on the drill string between the plurality of ranging devices and is operable to provide a non-conducting contact with the formation. During drilling operations, the plurality of ranging devices provide conducting contact with a formation while the at least one insulator member provides non-conducting contact with the formation so to enhancing ranging operations while drilling. A method of modeling and simulating drill string response is provided to identify locations along the drill string for positioning insulator members.

Abstract: The invention provides derivatives and analogues of triazatetracyclo[7.7.0.01,13,02,7]-hexadeca-2,4,6,10,12-pentaenes, 5,7,11-triazatetracyclo[8.7.0.01,6,012,17]-heptadeca-6,8,12,14,16-pentaenes, pharmaceutical compositions comprising these compounds and methods for treatment of hepatitis C viral infections using these compounds.

Abstract: This invention relates to tetrahydropyranonaphthyridines derivatives having formula (III) or IV: and analogues of the tetrahydropyranonaphthyridines derivatives. The invention also relates to pharmaceutical compositions comprising these compounds and methods for treatment of tuberculosis using these compounds.

Abstract: An embodiment includes a method that includes performing a directional drilling operation. The method also includes receiving data from one or more sensors, wherein at least one of the one or more sensors output data related to a performance attribute of a downhole component that is from a group consisting of a downhole drilling motor and a rotary steerable tool. The downhole component comprises part of a drill string that is used to perform the directional drilling operation. The performance attribute is selected from a group consisting of rotations per unit of time of the downhole component, operating differential pressure across the downhole component and torque output of the downhole component. The method also includes displaying the data in a graphical and numerical representation on a graphical user interface screen.

Abstract: An apparatus (50) for drilling a wellbore that transverses a subterranean hydrocarbon bearing formation. The apparatus (50) includes a drill string (52) having an inner fluid passageway (66). A drill bit (64) is disposed at a distal end of the drill string (52) and is operable to rotate relative to at least a portion of the drill string (52). A fluid motor (54) is disposed within the drill string (52) and is operable to rotate the drill bit (64) in response to a circulating fluid received via the inner fluid passageway (66) of the drill string (52). The fluid motor (54) has a stator (68) with (n) lobes and a rotor (70) with (n?1) lobes. The stator (68) includes an inner surface formed from a first material and the rotor (70) includes an outer surface formed from a second material that is dissimilar to the first material.

Abstract: A method for treating neoplastic disorders such as lymphomas, adenocarcinomas, mastocytomas, myelomas, pulmonary tumors, and macrophage tumors is provided. The method utilizes compounds containing a cross-conjugated cyclopentenone structure, but lacking an .alpha.,.beta. unsaturated .gamma.-lactone moiety.