Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: An a.c. Resonance Transformer for operating at a predetermined frequency. The transformer comprises a resonant .pi.-type or T-type stage. The .pi.-type stage includes three series connected four-terminal networks. The first of the networks and the third of the networks includes a shunt reactor of a first type. The second of the networks includes two series connected second type reactors and a first type reactor shunt connected to the junction between the second type reactors. The reactors in the second of the networks are sized so that when an input signal of a predetermined frequency is applied to the input of the first of the networks, a 180.degree. phase shift is provided between the phase angle of the input and output voltage vectors of the second of the networks and so that a zero input impedance is provided when the output is short circuited.

Abstract: A crutch has a piston 3 and cylinder 2 arrangement connected through a manually controlled valve (30, 54) and two one way ball valves 22,24 to a reservoir 12. A working fluid partly liquid and partly gas is compressed in the reservoir 12 and by manipulating the valve 30, 54 the user shortens the crutch by applying force between the handle 15 and the tip 5 and further manipulation of the valve 30,54 permits the liquid to resist shortening of the crutch.