Patents by Inventor John L. Krstenansky

John L. Krstenansky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiolabeled anticoagulant peptides
    Patent number: 5279812
    Abstract: This invention relates to the usage of anticoagulant peptide derivatives that are iodinated.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: January 18, 1994
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: John L. Krstenansky, Simon J. T. Mao
  • Cyclic anticoagulant peptides
    Patent number: 5236898
    Abstract: This invention relates to cyclic peptide derivatives which are useful anticoagulant agents.
    Type: Grant
    Filed: September 20, 1991
    Date of Patent: August 17, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: John L. Krstenansky, Simon J. T. Mao
  • Anticoagulant peptides
    Patent number: 5232912
    Abstract: This invention relates to peptide derivatives which are useful anticoagulant agents.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: August 3, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: John L. Krstenansky
  • Cyclic anticoagulant peptides
    Patent number: 5192745
    Abstract: This invention relates to cyclic peptide derivatives which are useful anticoagulant agents.
    Type: Grant
    Filed: September 23, 1991
    Date of Patent: March 9, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventors: John L. Krstenansky, Simon J. T. Mao
  • Anticoagulant peptides
    Patent number: 5192747
    Abstract: The invention relates to peptide derivatives which are useful anticoagulant agents.
    Type: Grant
    Filed: December 3, 1991
    Date of Patent: March 9, 1993
    Assignee: Merrell Dow Pharmaceuticals Inc.
    Inventor: John L. Krstenansky
  • Anticoagulant peptide alcohols
    Patent number: 4971953
    Abstract: This invention relates to peptide derivatives which are useful anticoagulant agents.
    Type: Grant
    Filed: April 3, 1990
    Date of Patent: November 20, 1990
    Assignee: Merrell Dow Pharmaceuticals
    Inventor: John L. Krstenansky
  • 5H-6-oxo-2,3,4,4a,7,7a-hexahydropyrano[2,3-b]pyrrole and the preparation thereof
    Patent number: 4535169
    Abstract: Conformationally restricted peptide analogs incorporating a rigid .beta.-bend are formed by replacing a portion of the peptide backbone chain with a bicyclic heterocycle, 5H-6-oxo-2,3,4,4a,7,7a-hexahydropyrano[2,3-b]pyrrole. Properly substituted derivatives of the pyranopyrrole are conformationally rigid and cannot assume non-.beta.-bend conformations in the interior of the peptide chain, while the terminal binding residues are maintained in the proper orientation for receptor interaction. Also described are a novel intermediate for preparation of the peptide analogs and a method for preparation of the intermediate.
    Type: Grant
    Filed: September 12, 1983
    Date of Patent: August 13, 1985
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: John L. Krstenansky, Bruce L. Currie