Abstract: This invention relates to methods of screening for anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof, for potential use in treating or preventing PACAP-associated photophobia or light aversion, and therapeutic compositions containing and methods of using anti-PACAP antibodies, or anti-PACAP receptor antibodies, and antigen binding fragments thereof.

Abstract: Systems and methods for facilitating user engagement with units of work assigned within a collaboration environment are presented herein. Implementations may: manage environment state information maintaining a collaboration environment, the environment state information the work unit records including values of an approval state parameter; effectuate presentation of a user interface of the collaboration environment, the user interface displaying individual work unit pages for individual units of work that include a set of user interface elements available for selection by the users, individual user interface elements in the set corresponding to different ones of the values of the approval state parameter; obtain user input information conveying user input characterizing the selection of the individual user interface elements; update the work unit records based on the user input information; and/or other perform other operations.

Abstract: The present application relates generally to tubes, such as thin walled catheter liners with small wall thicknesses (e.g., less than 1 mm), including crosslinked fluoropolymers, e.g., crosslinked poly(tetrafluoroethylene). The disclosure further provides methods of manufacturing such tubes and systems for manufacturing such tubes.

Abstract: The invention relates to a process for preparing heterocyclic amide derivatives, to novel polymorphic forms obtained from said process and the use of said polymorphic forms for use in the treatment and prophylaxis of cancer.

Abstract: A controlled extraction of an electronic connector from an electronic circuit board includes a press mechanism of a device positioned in spaced relation over a base fixture of the device. The base fixture receiving an electronic circuit board which includes a connector. Shafts of a removal tool of the press mechanism can be inserted into a series of openings in the connector, respectively, in response to applying a downward force to the press mechanism. A capturing element on each of the shafts can be actuated where the capturing element couples to a wall defining the opening of each of the openings. The connector can be removed from the electronic circuit board by applying an upward force to the press mechanism which removes the connector with the capturing element of the shafts coupled to the wall of the opening, and releasing the press mechanism from the base fixture.

Abstract: Omni-directional orthogonally-polarized antenna system for MIMO applications are disclosed herein. An example antenna system comprises two arrays of horizontally polarized radiating elements, and two arrays of vertically polarized radiating elements, each array having roughly 180-degree radiation pattern, disposed about a central axis in a common horizontal plane, arrays of common polarization separated by 180-degrees. Also, the example antenna system includes at least one printed circuit board having a saw tooth pattern, wherein uniform coverage in both vertical and horizontal polarization over 360 degrees is provided using beamforming and polarization diversity.

Abstract: A process for forming a fluidic module (150) with integrated fluid separation includes positioning a first positive passage mold (115A) of a first fluid passage (170) having a tortuous shape within a volume of binder-coated ceramic powder (110A) and positioning a second positive passage mold (115B) of a second fluid passage (175) having a tortuous shape within the volume of ceramic powder (110A) and spaced apart from the first positive passage mold (115A). The process further includes positioning a powder interconnect (120) adjacent to a portion of each of the first (115A) and second positive passage molds (115B) within the volume of ceramic powder (110A), pressing the volume of ceramic powder (110A, HOB) with the first and second positive passage molds (115A, 115B) and the powder interconnect (120) inside to form a pressed body (148), heating the pressed body to remove the first and second positive passage molds (115A, 115B), and sintering the pressed body (148) to form a closed-porosity ceramic body (150).

Abstract: A combination battery and battery charger construct for a vehicle such as an industrial truck. The battery comprises a battery charger construct that is attached to the battery so that the battery charger construct is resident on the battery. The battery charger construct comprises a battery chargers or battery chargers. A socket communicates with the battery charger(s) of the battery charger construct, and provides an electrical current input to the battery charger construct. The device is used with batteries for industrial vehicles that have an output of 90 volts or less.

Abstract: Solar power generation panels added on a transportation vehicle have a layout wherein power output of the panels varies according to an azimuth orientation of the vehicle. A controller includes a database of calibration curves relating an expected power output to a respective range of the azimuth orientation according to different solar altitude angles. A self-learning sequence is performed which (a) collects a magnitude of power output while the vehicle traverses the respective range of the azimuth orientation, (b) identifies a current solar altitude angle, and (c) stores a resulting calibration curve. A parking sequence comprises (a) selecting a calibration curve according to solar altitude angle, (b) determining a target vehicle azimuth angle which optimizes a cumulative power output based on the calibration curve and solar azimuth, and (d) initiating a movement of the vehicle to orient it at the target vehicle azimuth angle.

Abstract: A correlated color temperature (CCT) of one or more luminaires is controlled by obtaining a target CCT for the one or more luminaires and obtaining a first profile associated with a first luminaire of the one or more luminaires. A first target power for a first direct-current (DC) power input of the first luminaire and a second target power for a second DC power input of the first luminaire are calculated based on the target CCT and the first profile so that the first target power and the second target power drive the first luminaire to emit light at the target CCT. A first DC power supply is controlled to deliver the first target power to the first DC power input of the first luminaire and a second DC power supply is controlled to deliver the second target power to the second DC power input of the first luminaire.

Abstract: A technique of processing insurance data collected from a plurality of companies includes obtaining a company defined configuration that specifies how to extract a set of company generated data records from a data store and how the set of company generated data records is used by an application. The data store includes common data elements shared by the plurality of companies and company-specific data elements specified by a company. It further includes obtaining from the data store the set of company generated data records based on the company defined configuration. It further includes executing the application to process the company generated data records according to how the set of company generated data records is used by the application as specified by the company defined configuration.

Abstract: A method for proactively rebuilding user data in a plurality of storage nodes of a storage cluster in a single chassis is provided. The method includes distributing user data and metadata throughout the plurality of storage nodes such that the plurality of storage nodes can read the user data, using erasure coding, despite loss of two of the plurality of storage nodes. The method includes determining to rebuild the user data for one of the plurality of storage nodes in the absences of an error condition. The method includes rebuilding the user data for the one of the plurality of storage nodes. A plurality of storage nodes within a single chassis that can proactively rebuild the user data stored within the storage nodes is also provided.

Abstract: In general, scapular tethers and methods of using scapular tethers are provided. A tether is configured to be implanted in a body of a patient and to control movement of the patient's scapula. In an exemplary embodiment, the tether is configured to be attached to at least one body structure in a patient. The tether includes a flexible member configured to, when implanted in the patient, flex in response to movement of the patient's scapula accompanying arm movement of the patient.

Abstract: A vehicle includes a transmission that performs a method of operating a clutch of a vehicle. The vehicle includes the clutch, an actuator device and a processor. The actuator device includes a piston movable to operate the clutch. The processor is configured to receive a pressure signal indicative of a selected fluid pressure for operating the clutch, determine a position for the piston in the actuator device from the pressure signal, and move the piston to the position to operate the clutch at the selected fluid pressure.

Abstract: Provided herein are methods of increasing T-cell function and T-cells produced by these methods. Also provided herein are methods of treating a subject using T-cells produced by these methods.

Abstract: Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

Abstract: Systems and methods for informed mobility platform for an item processing supervisor within a distribution facility are disclosed. In one embodiment, a supervisor mobile terminal for electronically managing item processing activities associated with a distribution facility is provided. The terminal may include a transceiver circuit configured to wirelessly communicate with a server computer a plurality of sets of data relating to the item processing activities. The terminal may further include a user interface configured to display the plurality of sets of data and a controller in data communication with the transceiver circuit and the user interface. The controller may be configured to control the user interface to modify the at least one set of data and control the transceiver circuit to wirelessly communicate the modified data with the server computer such that the at least one set of data stored in the server computer is updated with the modified data.

Abstract: A correlated color temperature (CCT) of one or more luminaires is controlled by obtaining a target CCT for the one or more luminaires and obtaining a first profile associated with a first luminaire of the one or more luminaires. A first target power for a first direct-current (DC) power input of the first luminaire and a second target power for a second DC power input of the first luminaire are calculated based on the target CCT and the first profile so that the first target power and the second target power drive the first luminaire to emit light at the target CCT. A first DC power supply is controlled to deliver the first target power to the first DC power input of the first luminaire and a second DC power supply is controlled to deliver the second target power to the second DC power input of the first luminaire.

Abstract: A method for forming and installing a retaining ring comprises: feeding a wire in a linear path into a forming die having a circular bore; forming, using the forming die, the wire into a formed ring having a ring shape; transferring the formed ring from the forming die to a transfer puck; and installing the formed ring, as a retaining ring, in a tube of a product assembly. The formed ring is maintained in a constrained state between forming in the forming die and installation in the product assembly. A system for forming and installing a retaining ring into a product assembly includes a forming die configured to form a wire into a formed ring having a ring shape; and a transfer puck to transfer the formed ring from the forming die. The formed ring is maintained in a constrained state from forming through installation.

Abstract: A system may determine one or more data sources which the system is configured to access. The system may provide a set of application programming interfaces (APIs) for interacting with data stored in one or more data sources. The APIs may be accessible to one or more web applications which the system is configured to serve. The system may determine that a web application has requested an operation for interacting with the data through one or more APIs in the set of APIs. The system may determine one or more responses based at least in part on the operation requested by the web application. The system may provide the response(s) to the web application.