Patents by Inventor John Lezdey

John Lezdey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial coatings
    Patent number: 8084132
    Abstract: There is provided a two component polyurethane coating system which contains anti-microbial complexes consisting of phenol complexes which provide anti-microbial characteristics to the coating system and improved abrasion resistance. There is also provided substrates coated with the antimicrobial coatings.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: December 27, 2011
    Assignee: World Pharmaceutical Trust
    Inventor: John Lezdey
  • Anti-microbial compositions and polymers
    Patent number: 7828885
    Abstract: Anti-microbial compositions, polymers and paints having incorporated therein at least one phenolic complex. Preferably a chloroxylenol complex is utilized for topical treatment of a patient with a bacterial or viral skin infection.
    Type: Grant
    Filed: January 17, 2008
    Date of Patent: November 9, 2010
    Assignee: World-Pharm Trust
    Inventor: John Lezdey
  • Method of treatment
    Publication number: 20080234225
    Abstract: A method and composition for preventing the formation of lesions in a patient having a site of inflammation by the use of a cromolyn compound. The cromolyn compound is used with a composition containing penetrating aids.
    Type: Application
    Filed: March 15, 2004
    Publication date: September 25, 2008
    Inventors: John Lezdey, Darren Lezdey
  • DNA for expression of alpha 1-antitrypsin in methylotropic yeast
    Patent number: 7270979
    Abstract: Alpha 1-antitrypsin is prepared by growing in a fermentor methylotropic yeast transformants containing in their genome at least one copy of DNA encoding alpha 1-antitrypsin, in operational linkage with DNA encoding a signal sequence, which is effective for directing secretion of proteins from the host cells, DNA constructs and recombinant yeast strains used for the expression and secretion of alpha 1-antritrypsin are also provided. The fermentation medium requires a pH of 6.5 to 7.5. The fermentation is at a pH between 5 and 6.8.
    Type: Grant
    Filed: September 26, 2003
    Date of Patent: September 18, 2007
    Assignee: Alphamed Pharmaceuticals Corp
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Surgical and examination gloves
    Patent number: 6684405
    Abstract: An examination or surgical glove having an inner coating of a compound which prevents the degranulation of mast cells which releases medicators of inflammation. The coating includes anti-mast cell and anti-inflammatory agents such cromolyn compounds and human type protease inhibitors.
    Type: Grant
    Filed: June 5, 2001
    Date of Patent: February 3, 2004
    Inventor: John Lezdey
  • Treatment of osteocarcinoma with alpha-1—antitrypsin or secretory leucocyte protease inhibitor
    Patent number: 6670325
    Abstract: The present invention relates to the treatment of cancerous conditions in mammals by the administration to the site of disease compositions containing serine protease inhibitor. The cancerous conditions include osteocarcinomas, melanoma, Karopsi sarcoma and keratosis. The compositions are also useful to relieve the pain associated with the disease.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: December 30, 2003
    Assignee: Alpha Med Pharmaceuticals Corp.
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Topical wound therapeutic compositions
    Patent number: 6573249
    Abstract: There is provided a composition for healing burns and wounds in mammals, which contains a cromolyn compound or the combination of a cromolyn compound and hyaluronic acid a corticosteroid. Advantageously, elements found in amniotic fluid are also included.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: June 3, 2003
    Assignee: AlphaMed Pharmaceutical Corp.
    Inventors: John Lezdey, Darren Lezdey
  • Treatment of collagen related diseases
    Patent number: 6566331
    Abstract: The present invention provides for the treatment of a patient suffering from a collagen related disease utilizing a serine protease inhibitor. The treatment includes the use of a corticosteroid that is administered separately or in combination. The serine proteases preferred are alpha 1-antitrypsin, alpha 2-macroglobulin and secretory leucocyte protease inhibitor.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: May 20, 2003
    Assignee: Alphamed Pharmaceutical Corp
    Inventors: Darren Lezdey, K. Anne Kronis, John Lezdey
  • Anti-cancer compositions
    Publication number: 20030077266
    Abstract: The present invention relates to the treatment of cancerous conditions in mammals by the administration to the site of disease compositions containing serine protease inhibitor. The cancerous conditions include osteocarcinomas, melanoma, Karopsi sarcoma and keratosis. The compositions are also useful to relieve the pain associated with the disease.
    Type: Application
    Filed: October 19, 2001
    Publication date: April 24, 2003
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Cromolyn for eye and ear infections
    Patent number: 6511960
    Abstract: The present invention provides a method and composition for treating eye and ear inflammation and eye and ear infections. The compositions contain a cromolyn compound alone or in combination with a corticosteroid. A steroidal antiphlogistic compound, a non-steroidal antiphlogistic compound and optionally hyaluronic acid may be added.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: January 28, 2003
    Assignee: Alphamed Pharmaceuticals Corp
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Oral methods of treatment
    Publication number: 20030007960
    Abstract: A method is provided for the treatment of non-pulmonary diseases and injuries by the oral administration of a stabilized protease inhibitor that transgresses the gastrointestinal tract. Crystalline, crosslinked and polyethylene glycol adducts can be used as well as coated protease inhibitors and coated stabilized protease inhibitors.
    Type: Application
    Filed: September 20, 2001
    Publication date: January 9, 2003
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Oral methods of treatment
    Publication number: 20030007959
    Abstract: A method is provided for the treatment of pulmonary diseases and acquired immune disease by the oral administration of a stabilized protease inhibitor that transgresses the gastrointestinal tract. Crystalline crosslinked and polyethylene glycol adducts can be used as well as coated protease inhibitors and coated stabilized protease inhibitors.
    Type: Application
    Filed: June 20, 2001
    Publication date: January 9, 2003
    Inventors: John Lezdey, Darren Lezdey
  • Surgical and examination gloves
    Publication number: 20020189001
    Abstract: An examination or surgical glove having an inner coating of a compound which prevents the degranulation of mast cells which releases medicators of inflammation. The coating includes anti-mast cell and anti-inflammatory agents such cromolyn compounds and human type protease inhibitors.
    Type: Application
    Filed: June 5, 2001
    Publication date: December 19, 2002
    Inventor: John Lezdey
  • DNA for expression of alpha 1-antitrypsin in methylotrophic yeast
    Publication number: 20020164695
    Abstract: Alpha 1-antitrypsin is prepared by growing methylotropic yeast transformants containing in their genome at least one copy of DNA encoding alpha 1-antitrypsin, in operational linkage with DNA encoding a signal sequence, which is effective for directing secretion of proteins from the host cells, DNA constructs and recombinant yeast strains used for the expression and secretion of alpha 1-antritrypsin are also provided. The fermentation medium requires a pH of 6.5 to 7.5.
    Type: Application
    Filed: October 16, 2001
    Publication date: November 7, 2002
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Method for treating infectious viral diseases
    Patent number: 6468557
    Abstract: The present invention provides for the treatment of an individual suffering from infections from herpes virus or human papilloma virus by utilizing a cromolyn compound. The treatment includes the use of a corticosteroid or L-lysine that can be administered separately or in combination.
    Type: Grant
    Filed: January 5, 2001
    Date of Patent: October 22, 2002
    Assignee: AlphaMed Pharmaceutical Corp.
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Lubrication composition
    Patent number: 6428791
    Abstract: A lubricating composition for use in mucosal areas is provided to enhance sexual performance. The composition contains combination of a compound which enhances blood circulation to body parts and/or increase nitrous oxide levels at the site of administration together with a compound which can generate heat without any substantial irritation or create the feel of heat in a lubrication base. Preferably, the composition is homeopatic.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: August 6, 2002
    Assignee: Alphamed Pharmace Vticals, Corp
    Inventors: John Lezdey, Jarett Lezdey
  • Cromolyn for eye and ear infections
    Publication number: 20020091100
    Abstract: The present invention provides a method and composition for treating eye and ear inflammation and eye and ear infections. The compositions contain a cromolyn compound alone or in combination with a corticosteroid. A steroidal antiphlogistic compound, a non-steroidal antiphlogistic compound and optionally hyaluronic acid may be added.
    Type: Application
    Filed: January 5, 2001
    Publication date: July 11, 2002
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Antimicrobial compositions
    Publication number: 20020064544
    Abstract: The invention provides antimicrobial composition which contain phenols complexed with polycarboxylic acid and a quaternary amine compound to form a long lasting film which can be sprayed on surfaces or combined with a polymer
    Type: Application
    Filed: November 23, 2001
    Publication date: May 30, 2002
    Inventors: John Lezdey, Jarett Lezdey
  • Cosmetic compositions containing cromolyn compounds for revitalizing the skin
    Patent number: 6379684
    Abstract: Cosmetic compositions and methods are provided for revitalizing the skin especially where it is placed in an environment that can cause injury to the skin. The compositions contain an effective amount of cromolyn compounds to provide a prophylactic or repairing effect.
    Type: Grant
    Filed: May 2, 2001
    Date of Patent: April 30, 2002
    Assignee: Alphamed Pharaceutical Corp.
    Inventors: John Lezdey, K. Anne Kronis, Darren Lezdey
  • Antimicrobial compositions
    Publication number: 20020028229
    Abstract: The invention provides antimicrobial compositions which contain a phenol complex with a film forming complex of a polycarboxylic acid and a microbicide containing at least two quaternary amine groups.
    Type: Application
    Filed: January 25, 2000
    Publication date: March 7, 2002
    Inventors: John Lezdey, Jarett R. Lezdey