Abstract: One or more techniques for optimizing cancer classification based on covariate characteristics is disclosed. In a first approach, an analytics system may determine separate cutoff thresholds for positively detecting disease signal for different labels for a covariate characteristic. The system may subdivide training samples based on their labels for the covariate characteristic, to separately determine the cutoff thresholds. In other approaches, the system may train disparate classifiers for each population. The system separates the training samples based on their labels for the covariate characteristic, and separately trains classifiers to generate a signal vector representing an amount of disease signal detected in a sample. The classifiers may be trained on different feature sets as determined based on mutual information gain, genomic region coverage, and healthy activation fraction.

Abstract: Systems and methods for defending against volumetric attacks, implemented in a cloud-based system. Embodiments include steps of, monitoring flows and a rate of requests to a Data Center (DC); receiving a request from an address to the DC, the request being for a service in a cloud-based system; determining if the address has been successfully authenticated within a past predetermined time period; responsive to the address not having been successfully authenticated within the past time period, and one of (i) the rate of requests being above a threshold or (ii) the number of flows being above a threshold, placing the address in a penalty box for a predetermined amount of time; and blocking requests from the address in the penalty box for the predetermined amount of time.

Abstract: A user equipment (UE) can be a mobile terminating (MT) device that may receive data from another UE or other network element via a telecommunication network. When a small data payload is available for an MT UE, a base station of the telecommunication network can send a paging message to the UE that includes a Mobile Terminating Small Data Transmission (MT-SDT) paging cause. Based on the MT-SDT paging cause in the paging message, the UE can use Small Data Transmission (SDT) procedures to respond to the paging message. The SDT procedures can allow the UE to obtain the small data payload while the UE remains in a Radio Resource Control (RRC) Inactive state.

Abstract: The automated generation of a natural language explanation of what code does. The code is structured to perform tasks because the code itself semantically specifies that those tasks are to be performed. A task-centric representation of the code is automatically generated that includes a task representation of each of some or all of the tasks to be performed as specified by the code. Natural language utterances are then automatically generated by generating a corresponding natural language utterance that semantically describes in natural language the corresponding task represented by the corresponding task representation. Controls are rendered for each natural language utterance that each permit a user to edit the corresponding natural language utterance. After editing, the code itself may be automatically modified or regenerated to reflect the changed natural language utterances.

Abstract: In some embodiments, an affixed group of pharmaceutical vials with frangible connectors includes: a plurality of pharmaceutical vials arranged as a group of pharmaceutical vials, each of the plurality of pharmaceutical vials shaped and positioned to minimize a total volume of the group of pharmaceutical vials, each of the pharmaceutical vials including at least one external side with a surface configured to reversibly mate with a corresponding external side and a surface of an adjacent pharmaceutical vial; and a plurality of frangible connectors, wherein at least one frangible connector is affixed to the surface of at least two of the plurality of pharmaceutical vials within the group of pharmaceutical vials, and at least one frangible connector is affixed to each of the plurality of pharmaceutical vials.

Abstract: An antenna for an electronic device comprising of a metal-sheet antenna and an antenna feed connecting the metal-sheet antenna to a radio frequency (RF) printed circuit board (PCB). A screw configured to operate as a ground feed for the metal-sheet antenna and to provide mechanical support in the electronic device wherein the screw is further configured to provide radiation for additional bands for the antenna. The metal-sheet antenna supports a first band, and the screw supports a second band, based on dimensions of a screw boss, and a third band, based on a gap between the screw boss and the metal-sheet antenna.

Abstract: Embodiments described herein provide a technique to facilitate the synchronization of workgroups executed on multiple graphics cores of a graphics core cluster. One embodiment provides a graphics core including a cache memory and a graphics core coupled with the cache memory. The graphics core includes execution resources to execute an instruction via a plurality of hardware threads and barrier circuitry to synchronize execution of the plurality of hardware threads, wherein the barrier circuitry is configured to provide a plurality of re-usable named barriers.

Abstract: A method includes obtaining an under-display camera (UDC) image captured using a camera located under a display. The method also includes processing, using at least one processing device of an electronic device, the UDC image based on a machine learning model to restore the UDC image. The method further includes displaying or storing the restored image corresponding to the UDC image. The machine learning model is trained using (i) a ground truth image and (ii) a synthetic image generated using the ground truth image and a point spread function that is based on an optical transmission model of the display.

Abstract: An exemplary method and system is disclosed that facilitate the integration of multiplexed single-cell impedance cytometry in a high throughput format, which can be deployed upstream from microfluidic sample preparation and/or downstream to microfluidic cell separation. In exemplary method and system may employ impedance-based quantification of cell electrophysiology on the same microfluidic chip (i.e., “on-chip”) to provide distinguishing phenotypic information on the sample, without the need for additional sample handling, preparation or dilution steps as would be needed for other flow cytometry techniques.

Abstract: Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders.

Abstract: Disclosed are antibodies thereof that bind to coagulation factor XI (FXI) and/or its activated form factor XIa (FXIa), or to fragments of FXI and/or FXIa, and compositions containing the antibodies. Also disclosed are methods of preparing the antibodies and use of the antibodies for treating and/or preventing coagulation associated conditions such as thrombosis and complications or conditions associated with thrombosis.

Abstract: A method includes identifying, using at least one processing device of an electronic device, a spatially-variant point spread function associated with an under-display camera. The spatially-variant point spread function is based on an optical transmission model and a layout of a display associated with the under-display camera. The method also includes generating, using the at least one processing device, a ground truth image. The method further includes performing, using the at least one processing device, a convolution of the ground truth image based on the spatially-variant point spread function in order to generate a synthetic sensor image. The synthetic sensor image represents a simulated image captured by the under-display camera. In addition, the method includes providing, using the at least one processing device, the synthetic sensor image and the ground truth image as an image pair to train a machine learning model to perform under-display camera point spread function inversion.

Abstract: A device including a housing that is substantially impermeable to ultraviolet radiation having a wavelength of from 280 nm to 400 nm, and at least one window defined in the housing, the window including a UV-C radiation band-pass mirror film having a multiplicity of alternating first and second optical layers collectively transmitting UV-C radiation at a wavelength from at least 100 nm to less than 280 nm and not transmitting UV-A and UV-B radiation at a wavelength of from 280 nm to 400 nm, and an ultraviolet radiation source positioned within the housing, the ultraviolet radiation source being capable of emitting ultraviolet radiation at one or more wavelength from 100 nm to 400 nm. The device optionally further includes an ultraviolet mirror film positioned within the housing so as to reflect ultraviolet radiation emitted by the ultraviolet radiation source. A method of disinfecting a material is also disclosed.

Abstract: Methods, systems, and devices for wireless communication are described. For example, the described techniques provide for a first device (e.g., a cellular modem or user equipment (UE)) mapping quality of service flows of a first radio access technology (e.g., cellular) to service classes of a second RAT (e.g., Wi-Fi). The first device may communicate mapping information that indicates the mapping to a second network device (e.g., a router). The first device and the second device may communicate various packets via the quality of service flows and the service classes.

Abstract: A memory controller monitors memory command selected for dispatch to the memory and sends commands controlling a read clock state. A memory includes a read clock circuit and a mode register. The read clock circuit has an output for providing a hybrid read clock signal in response to a clock signal and a read clock mode signal. The read clock circuit provides the hybrid read clock signal as a free-running clock signal that toggles continuously, and as a strobe signal that is active only in response to the memory receiving a read command.

Abstract: An electric-vehicle frame includes a mid-section and an end section. The mid-section has first and second frame rails spaced from each other by a first distance along a cross-vehicle axis defining a battery compartment therebetween. The end-section has first and second frame rails spaced from each other by a second distance along the cross-vehicle axis smaller than the first distance. A first connector is fixed to the first frame rail of the mid-section and to the first frame rail of the end-section. A second connector is fixed to the second frame rail of the mid-section and to the second frame rail of the end-section.

Abstract: Authenticating a mobile user device with a mobile network operator in advance of an MNO authentication request from the mobile user device can be done by a satellite network sending an authentication request to the MNO system, obtaining a set of authentication vectors related to the mobile user device, storing them into a proxy home location register, receiving the MNO authentication request from the mobile user device, generating an authentication request response based on the authentication vectors, sending the authentication request response to the mobile user device, receiving an authentication response including a received signed response, comparing the received signed response with the stored signed response, and if the received signed response and stored signed response match, deem that to be a successful authentication, add an MNO location update message to a request queue and forward the MNO location update message to the MNO system over the channel when available.

Abstract: One embodiment can provide a photovoltaic roof tile. The photovoltaic roof tile can include a transparent front cover, a transparent back cover, and a plurality of polycrystalline-Si-based photovoltaic structures positioned between the front cover and the back cover. A respective polycrystalline-Si-based photovoltaic structure has a front surface facing the front cover and a back surface facing the back cover. The photovoltaic roof tile can further include a paint layer positioned on a back surface of the back cover facing away from the front cover. A color of the paint layer substantially matches a color of the front surface of the respective polycrystalline-Si-based photovoltaic structure.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: Systems and methods for a multi-layered peel-away sheath assembly for insertion of a blood pump, the peel-away sheath assembly including a sheath hub and a sheath body having a proximal end that is connected to the sheath hub, and a distal end. The sheath body comprises multiple layers including a reinforcing layer. The reinforcing layer improves flexibility and kink resistance of the assembly The reinforcing layer can comprise LCP, PEBAX, stainless steel, Nitinol, or Kevlar. The reinforcing layer may be a laser-cut hypotube or a braided or coiled filament. A first layer material and a third layer material are thermoplastics, including PEBAX or TPU. The reinforcing layer has at least one discontinuity, which is aligned with peel-away lines in the sheath body to allow an operator to peel-away the assembly. The peel-away lines are formed of inner notches, outer notches, or both. The sheath hub also includes a discontinuity to allow the sheath hub to peel-away.