Patents by Inventor John M. Gleisner
John M. Gleisner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6780651Abstract: A method of making strip for testing for the presence of an analyte generally comprises providing a support member which includes a spreading layer and a reagent layer, and a capillary in communication with the support layer and spreading layer for transporting a sample of body fluid thereto.Type: GrantFiled: June 7, 2001Date of Patent: August 24, 2004Assignee: Roche Diagnostics Operations, Inc.Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
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Patent number: 6750962Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.Type: GrantFiled: April 10, 2001Date of Patent: June 15, 2004Assignee: Amira MedicalInventors: Joel S. Douglas, Jeffrey N. Roe, John H. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
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Publication number: 20020067484Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.Type: ApplicationFiled: April 10, 2001Publication date: June 6, 2002Inventors: Joel S. Douglas, Jeffrey N. Roe, John H. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
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Publication number: 20020052050Abstract: A method of making strip for testing for the presence of an analyte generally comprises providing a support member which includes a spreading layer and a reagent layer, and a capillary in communication with the support layer and spreading layer for transporting a sample of body fluid thereto.Type: ApplicationFiled: June 7, 2001Publication date: May 2, 2002Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
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Patent number: 6285454Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.Type: GrantFiled: December 7, 1998Date of Patent: September 4, 2001Assignee: Mercury Diagnostics, Inc.Inventors: Joel S. Douglas, Jeffrey N. Roe, John E. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
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Patent number: 6271045Abstract: A strip for testing for the presence of an analyte generally comprises a support member which contains a spreading layer and a reagent layer, and a capillary tube in communication with the support layer and spreading layer for transporting a sample of body fluid thereto. A method of testing a fluid for the presence or concentration of an analyte is also provided which generally includes providing a test strip with a support member, a spreading layer, and a reagent layer on the spreading layer. A capillary tube is provided on the support member whereby a fluid containing an analyte to be tested is introduced into the tube and flows through the tube to the spreading layer and contacts the reagent layer.Type: GrantFiled: May 7, 1999Date of Patent: August 7, 2001Assignee: Amira MedicalInventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
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Patent number: 6242207Abstract: A dry chemistry reagent matrix composition is provided containing a matrix material and a reagent composition containing 3-methyl-6(sulfonate salt)-benzothiazolinone-(2)-hydrazone (MBTH-S), N-ethyl-N-(3-sulfopropyl)aniline, and an oxidase enzyme or a peroxidase enzyme or a mixture thereof. The dry chemistry reagent matrix composition is useful in reagent test strips for determining the presence or concentration of an analyte in a fluid sample, such as blood.Type: GrantFiled: October 4, 1999Date of Patent: June 5, 2001Assignee: Amira MedicalInventors: Joel S. Douglas, Karen R. Drexler, John M. Gleisner, John H. Priest
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Patent number: 6121011Abstract: This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount of reagent applied to the test device. The analytical test devices prepared by the methods of this invention are used to determine the presence or the quantity of an analyte in a liquid sample, such as whole blood.Type: GrantFiled: December 4, 1998Date of Patent: September 19, 2000Assignee: Amira MedicalInventors: Joel S. Douglas, John M. Gleisner
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Patent number: 5948695Abstract: A strip for testing for the presence of an analyte generally comprises a support member which contains a spreading layer and a reagent layer, and a capillary tube in communication with the support layer and spreading layer for transporting a sample of body fluid thereto. A method of testing a fluid for the presence or concentration of an analyte is also provided which generally includes providing a test strip with a support member, a spreading layer, and a reagent layer on the spreading layer. A capillary tube is provided on the support member whereby a fluid containing an analyte to be tested is introduced into the tube and flows through the tube to the spreading layer and contacts the reagent layer.Type: GrantFiled: June 17, 1997Date of Patent: September 7, 1999Assignee: Mercury Diagnostics, Inc.Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
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Patent number: 5876957Abstract: This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount of reagent applied to the test device. The analytical test devices prepared by the methods of this invention are used to determine the presence or the quantity of an analyte in a liquid sample, such as whole blood.Type: GrantFiled: January 8, 1998Date of Patent: March 2, 1999Assignee: Mercury Diagnostics, Inc.Inventors: Joel S. Douglas, John M. Gleisner
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Patent number: 5547702Abstract: A method for making a test strip is described. The test strip is generally a substrate, a layer disposed on the substrate and located near the distal end of the substrate. The layer typically contains a chemical reagent detection system capable of detecting the presence of a predetermined analyte in a sample of biological fluid, wherein the reagent detection system produces a detectable change in the layer in the presence of the analyte.Type: GrantFiled: July 8, 1994Date of Patent: August 20, 1996Assignee: Polymer Technology International CorporationInventor: John M. Gleisner
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Patent number: 5128171Abstract: A test strip for the detection of a predetermined substance in a fluid is described. This test strip is stable to storage and accelerated keeping test conditions and comprises a support having thereof a reagent layer wherein the reagent layer contains a dialyzed latex polymer and a reagent detection system which reacts with the substance to provide a detectable change.Type: GrantFiled: June 26, 1990Date of Patent: July 7, 1992Assignee: Polymer Technology InternationalInventor: John M. Gleisner
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Patent number: 4952515Abstract: A method for the detection of a predetermined substance in a fluid is described. The method uses a test strip that is stable to storage and accelerated keeping test conditions. A sample of a fluid containing an unknown quantity of a predetermined substance is contacted with a support having thereon a reagent layer wherein the reagent layer contains a dialyzed latex polymer and a reagent detection system which reacts with the substance to provide a detectable change. The detectable change can be determined qualitatively or quantitatively to determine the presence or the amount of the predetermined substance.Type: GrantFiled: February 10, 1989Date of Patent: August 28, 1990Assignee: Polymer Technology International Corp.Inventor: John M. Gleisner
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Patent number: 4814142Abstract: A diagnostic test strip for the detection of a analyte in a test fluid. The test strip has a reagent layer on a support layer. The reagent layer contains an analyte detection system in a non-particulate dialyzed latex polymer.Type: GrantFiled: May 22, 1987Date of Patent: March 21, 1989Assignee: Polymer Technology International Corp.Inventor: John M. Gleisner
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Patent number: D403975Type: GrantFiled: June 17, 1997Date of Patent: January 12, 1999Assignee: Mercury Diagnostics, Inc.Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner