Patents by Inventor John M. Gleisner

John M. Gleisner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6780651
    Abstract: A method of making strip for testing for the presence of an analyte generally comprises providing a support member which includes a spreading layer and a reagent layer, and a capillary in communication with the support layer and spreading layer for transporting a sample of body fluid thereto.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: August 24, 2004
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
  • Patent number: 6750962
    Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: June 15, 2004
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, Jeffrey N. Roe, John H. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
  • Publication number: 20020067484
    Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.
    Type: Application
    Filed: April 10, 2001
    Publication date: June 6, 2002
    Inventors: Joel S. Douglas, Jeffrey N. Roe, John H. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
  • Publication number: 20020052050
    Abstract: A method of making strip for testing for the presence of an analyte generally comprises providing a support member which includes a spreading layer and a reagent layer, and a capillary in communication with the support layer and spreading layer for transporting a sample of body fluid thereto.
    Type: Application
    Filed: June 7, 2001
    Publication date: May 2, 2002
    Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
  • Patent number: 6285454
    Abstract: A multi-use assay system accurately docks a removable test strip supporting a reagent-analyte reaction with an optics system including an LED, photodetector, and lenses or light pipes for directing light to and from the test strip. Docking is achieved using alignment fixturing, whereby an optics block holder is relied upon to align the test strip and test pad with the various optical components. Signals from the photodetector indicative of test strip reaction progress are provided to a processor for measuring the analyte.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: September 4, 2001
    Assignee: Mercury Diagnostics, Inc.
    Inventors: Joel S. Douglas, Jeffrey N. Roe, John E. Priest, John M. Gleisner, Charles C. Raney, David A. Hasker, Ryszard Radwanski, John Ramirez
  • Patent number: 6271045
    Abstract: A strip for testing for the presence of an analyte generally comprises a support member which contains a spreading layer and a reagent layer, and a capillary tube in communication with the support layer and spreading layer for transporting a sample of body fluid thereto. A method of testing a fluid for the presence or concentration of an analyte is also provided which generally includes providing a test strip with a support member, a spreading layer, and a reagent layer on the spreading layer. A capillary tube is provided on the support member whereby a fluid containing an analyte to be tested is introduced into the tube and flows through the tube to the spreading layer and contacts the reagent layer.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: August 7, 2001
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
  • Patent number: 6242207
    Abstract: A dry chemistry reagent matrix composition is provided containing a matrix material and a reagent composition containing 3-methyl-6(sulfonate salt)-benzothiazolinone-(2)-hydrazone (MBTH-S), N-ethyl-N-(3-sulfopropyl)aniline, and an oxidase enzyme or a peroxidase enzyme or a mixture thereof. The dry chemistry reagent matrix composition is useful in reagent test strips for determining the presence or concentration of an analyte in a fluid sample, such as blood.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: June 5, 2001
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, Karen R. Drexler, John M. Gleisner, John H. Priest
  • Patent number: 6121011
    Abstract: This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount of reagent applied to the test device. The analytical test devices prepared by the methods of this invention are used to determine the presence or the quantity of an analyte in a liquid sample, such as whole blood.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: September 19, 2000
    Assignee: Amira Medical
    Inventors: Joel S. Douglas, John M. Gleisner
  • Patent number: 5948695
    Abstract: A strip for testing for the presence of an analyte generally comprises a support member which contains a spreading layer and a reagent layer, and a capillary tube in communication with the support layer and spreading layer for transporting a sample of body fluid thereto. A method of testing a fluid for the presence or concentration of an analyte is also provided which generally includes providing a test strip with a support member, a spreading layer, and a reagent layer on the spreading layer. A capillary tube is provided on the support member whereby a fluid containing an analyte to be tested is introduced into the tube and flows through the tube to the spreading layer and contacts the reagent layer.
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: September 7, 1999
    Assignee: Mercury Diagnostics, Inc.
    Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner
  • Patent number: 5876957
    Abstract: This invention provides methods and apparatus for applying a reagent to an analytical test device. The methods and apparatus employ a nozzle and a flexible restrictor to accurate control the amount of reagent applied to the test device. The analytical test devices prepared by the methods of this invention are used to determine the presence or the quantity of an analyte in a liquid sample, such as whole blood.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: March 2, 1999
    Assignee: Mercury Diagnostics, Inc.
    Inventors: Joel S. Douglas, John M. Gleisner
  • Patent number: 5547702
    Abstract: A method for making a test strip is described. The test strip is generally a substrate, a layer disposed on the substrate and located near the distal end of the substrate. The layer typically contains a chemical reagent detection system capable of detecting the presence of a predetermined analyte in a sample of biological fluid, wherein the reagent detection system produces a detectable change in the layer in the presence of the analyte.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: August 20, 1996
    Assignee: Polymer Technology International Corporation
    Inventor: John M. Gleisner
  • Patent number: 5128171
    Abstract: A test strip for the detection of a predetermined substance in a fluid is described. This test strip is stable to storage and accelerated keeping test conditions and comprises a support having thereof a reagent layer wherein the reagent layer contains a dialyzed latex polymer and a reagent detection system which reacts with the substance to provide a detectable change.
    Type: Grant
    Filed: June 26, 1990
    Date of Patent: July 7, 1992
    Assignee: Polymer Technology International
    Inventor: John M. Gleisner
  • Patent number: 4952515
    Abstract: A method for the detection of a predetermined substance in a fluid is described. The method uses a test strip that is stable to storage and accelerated keeping test conditions. A sample of a fluid containing an unknown quantity of a predetermined substance is contacted with a support having thereon a reagent layer wherein the reagent layer contains a dialyzed latex polymer and a reagent detection system which reacts with the substance to provide a detectable change. The detectable change can be determined qualitatively or quantitatively to determine the presence or the amount of the predetermined substance.
    Type: Grant
    Filed: February 10, 1989
    Date of Patent: August 28, 1990
    Assignee: Polymer Technology International Corp.
    Inventor: John M. Gleisner
  • Patent number: 4814142
    Abstract: A diagnostic test strip for the detection of a analyte in a test fluid. The test strip has a reagent layer on a support layer. The reagent layer contains an analyte detection system in a non-particulate dialyzed latex polymer.
    Type: Grant
    Filed: May 22, 1987
    Date of Patent: March 21, 1989
    Assignee: Polymer Technology International Corp.
    Inventor: John M. Gleisner
  • Patent number: D403975
    Type: Grant
    Filed: June 17, 1997
    Date of Patent: January 12, 1999
    Assignee: Mercury Diagnostics, Inc.
    Inventors: Joel S. Douglas, Ryszard Radwanski, Brent G. Duchon, John H. Priest, David A. Hasker, John M. Gleisner