Patents by Inventor John M. Gruber

John M. Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing 2-oxindole-1-carboxamides
    Patent number: 5449788
    Abstract: The present invention provides a process for preparing 2-oxindole-1-carboxamides, comprising reacting N-acyl 2-oxindole-1-carboxamides with alcohols in the presence of aprotic weak Lewis acid catalysts. In certain processes of the present invention a 2-oxindole-1-carboxamide is prepared from a 2-oxindole by reacting the 2-oxindole with an acyl isocyanate to produce the N-acyl 2-oxindole-1-carboxamide as an intermediate, which is then reacted with alcohol in the presence of aprotic weak Lewis acid catalysts. The N-acyl 2-oxindole-1-carboxamide intermediate may be converted to the 2-oxindole-1-carboxamide without isolation.
    Type: Grant
    Filed: January 28, 1994
    Date of Patent: September 12, 1995
    Assignee: Catalytica, Inc.
    Inventor: John M. Gruber
  • Substituted N-(heterocyclic-substituted phenyl)-N'-benzylureas
    Patent number: 4950678
    Abstract: Novel substituted N-(heterocyclic-substituted phenyl)-N'-benzoyl-ureas, processed for producing these compounds, intermediates therefor, compositions thereof and the use of the compounds for the control of pests.
    Type: Grant
    Filed: July 27, 1989
    Date of Patent: August 21, 1990
    Assignee: Sandoz Ltd.
    Inventors: Robert L. Carney, John M. Gruber, Alfred S. T. Lui
  • Substituted N-benzoyl-N'-thienylureas
    Patent number: 4859699
    Abstract: Substituted N-benzoyl-N'-thienylureas, processes for making these compounds, intermediates therefor and the use of the compounds for the control of pests, and in particular for the control of insects and acarids.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: August 22, 1989
    Assignee: Sandoz Ltd.
    Inventors: Robert L. Carney, Alfred S. T. Lui, Fred Kuhnen, John M. Gruber
  • Preparation of alpha-cyanobenzyl esters
    Patent number: 4849536
    Abstract: A process for the preparation of .alpha.-cyanobenzyl esters of cyclopropane carboxylic acids and substituted alkanoic acids by treating a carboxylic acid and a benzaldehyde with a metal cyanide, followed by treatment with a sulfonyl halide.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: July 18, 1989
    Assignee: Sandoz Ltd.
    Inventor: John M. Gruber