Abstract: The disclosure relates to a sterilization apparatus which uses thermal or non-thermal plasma to disinfect surgical scoping devices such as endoscopes, gastroscopes, laparoscopes and the like. Aspect of the disclosure provide: (i) an apparatus for sterilizing inside an instrument channel formed with an insertion tube of a surgical scoping device, (ii) a whole-device sterilization apparatus for treating the entire exterior surface of a surgical scoping device, and (iii) an apparatus for cleaning and sterilizing a distal end face of an insertion tube of a surgical scoping device.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A treatment apparatus which uses thermal or non-thermal plasma to treat urinary tract infections (UTIs) by destroying bacteria. The apparatus comprises an elongate probe that includes a coaxial cable for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy, a probe tip connected at the distal end of the coaxial cable for receiving the RF and/or microwave EM energy, and a gas conduit for conveying gas to the probe tip. The probe tip comprises a first electrode connected to the inner conductor of the coaxial cable, and a second electrode connected to the outer conductor of the coaxial cable, and wherein the first electrode and second electrode are arranged to produce an electric field from the received RF and/or microwave EM energy across a flow path of gas received from the gas conduit to produce a thermal or a non-thermal plasma.

Abstract: A shim or badge is affixed to a golf club body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening and extend into the toe portion in the golf club body, the golf club head can provide increased stiffness in the topline, while lowering CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.

Abstract: In one aspect, an electronic gaming system that includes at least one memory device with instructions stored thereon, and at least one processor in communication with the at least one memory device, wherein the instructions, when executed by the at least one processor, cause the at least one processor to display a game interface including a game matrix and generate a game outcome of a base game comprising a plurality of displayed symbols within the game matrix. The displayed symbols include at least a first symbol and a second symbol. If a wild symbol is displayed on a spin, a counter configured to track a number of displayed wild symbols over a predetermined period of time is incremented. If the number of counted wild symbols satisfies a threshold within the predetermined period of time, the second symbol is converted to or replaced by the first symbol.

Abstract: An electronic gaming system including a memory with instructions stored thereon and a processor in communication with the memory is described. The instructions, when executed by the processor, cause the processor to cause display of an electronic game with a first theme, receive an input associated with a second theme, and transmit an identifier associated with the second theme to a host component. The instructions also cause the processor to receive content associated with the second theme and cause display of the electronic game with the second theme. The instructions further cause the processor to cause a game outcome for the electronic game to be stored in a game log wherein upon generation of a replay of the game outcome the replay includes the at least one symbol, and cause display of the game outcome.

Abstract: In one aspect, an electronic gaming system that includes at least one memory device with instructions stored thereon, and at least one processor in communication with the at least one memory device, wherein the instructions, when executed by the at least one processor, cause the at least one processor to display a game interface including a game matrix and generate a game outcome of a base game comprising a plurality of displayed symbols within the game matrix. The displayed symbols include at least a first symbol and a second symbol. If a wild symbol is displayed on a spin, a counter configured to track a number of displayed wild symbols over a predetermined period of time is incremented. If the number of counted wild symbols satisfies a threshold within the predetermined period of time, the second symbol is converted to or replaced by the first symbol.

Abstract: Systems and methods are provided for translation of text in an image, and presentation of a version of the image in which the translated text is displayed a manner consistent with the original image. Text segments are automatically translated from their original source language to a target language. In order to provide presentation of the translated text in a manner that closely matches the source text, various display attributes of the source text are detected (e.g., font size, font color, font style, etc.).

Abstract: Techniques for adjusting the strengths of signals received from a transmitter based on the transmitter's likely location are disclosed herein. An example method includes receiving, by one or more processors, location information corresponding to one or more respective areas expected to be visited by an individual; receiving, by the one or more processors, measurements indicative of signal strengths of one or more signals transmitted by a transmitter associated with the individual and received by one or more receivers configured to receive one or more signals transmitted by the transmitter, the one or more receivers being positioned at respective receiver locations corresponding to one or more respective areas; and adjusting, by the one or more processors, the received measurements indicative of the signal strengths of the one or more signals transmitted by the transmitter based on the one or more respective areas expected to be visited by the individual.

Abstract: A micro-bioelectrochemical cell (?-BEC) device is disclosed that includes from 4 to 96 microfluidically connected of chambers, in which each chamber encloses a volume of about 1 ?L to 2 ?L. A working electrode, reference electrode, and counting electrode contacts each volume. The ?-BEC device includes a support layer coated with a working electrode layer, a microfluidics layer containing a plurality of wells, and an electrical layer containing the reference and counter electrodes. Methods of using the ?-BEC device to perform bioelectrochemical measurements of cells are also disclosed.

Abstract: Provided herein is a method for treating a monocarboxylate transporter MCT4-mediated disorder in a subject in need thereof. The method comprises the step of administering to the subject a compound of structural Formula I and/or a salt thereof. The treatment of the monocarboxylate transporter MCT4-mediated disorder may inhibit activity of MCT4, or a mutant thereof, sometimes with at least a 100-fold selevtivity for MCT4 over MCT1.

Abstract: A sample preparation blister pack can include a plurality of reservoirs formed as blisters. The reservoirs can have an actuatable barrier layer and a seal barrier layer with contents of the reservoirs between the actuatable barrier layer and the seal barrier layer. The contents can be to facilitate isolating a biological component from a biological sample. The individual reservoirs can be adapted to release the contents through the seal barrier layer upon actuation of the actuatable barrier layer. The blister pack can have a width and a length and the reservoirs can be lined up along the length. In this example, a first reservoir contains an inert mechanical fluid and a second reservoir contains a reagent, a buffer, or a combination thereof.

Abstract: A charger system comprising a charging station including a plurality of nests for chargers is described. Each of the plurality of nests is designed to partially eject the charger when instructed to do so, and further comprises a nest lock to lock in the charger into the nest when not ejecting. The charger system interacting with a user account, enabling a user to request the charger, wherein the charger is ejected from the nest for a valid request.

Abstract: In an example of the method, a functionalized coating layer is applied in depressions of a patterned flow cell substrate. The depressions are separated by interstitial regions. A primer is grafted to the functionalized coating layer to form a grafted functionalized coating layer in the depressions. A hydrogel is applied on at least the grafted functionalized coating layer.

Abstract: An oxygen scavenging dressing includes a patient interface layer, an absorbent layer, a foam layer, an oxygen scavenging layer, and a film layer. The film layer is configured to seal with a patient's skin and define an inner volume within which the patient interface layer, the absorbent layer, the foam layer, and the oxygen scavenging layer are positioned.

Abstract: A method for delivering a plurality of packages is described. The method includes obtaining, via a processor, information associated with a delivery plan of the plurality of packages from at least one memory. Based on the information, the method includes determining, via the processor, a current location, and a destination location of a target container. In response to the determination, the method includes determining, via the processor, a movement plan to move the target container to the destination location. Based on the movement plan, the method includes activating, via the processor, a first set of motorized tiles to move the target container to the destination location. The method further includes receiving, via the processor, an updated movement plan from a server plan when a preset condition is met. Based on the updated movement plan, the method includes activating, via the processor, a second set of motorized tiles.

Abstract: A label modification unit may receive a label modification input that indicates a label modification associated with content being written to a label or erased from the label. The label modification unit may identify an area of the label that is associated with the label modification according to the label modification input. The label modification unit may determine, based on a size of the area, a spot size of a light beam that is configured to be emitted by a laser printhead to modify the content within the area. The label modification unit may determine, based on the spot size and the content, an optical path configuration for the laser printhead. The label modification unit may operate the laser printhead according to the optical path configuration to write the content to the area or erase the content from the area.

Abstract: A damper is provided within the cavity of a golf club head and spans substantially the full length of the striking face from heel-to-toe of the golf club head. One or more cutouts and/or other relief is provided in the damper to reduce the surface area of the damper that contacts the rear surface of the striking face. By reducing the surface area that the damper contacts the rear surface of the striking face, the full length damper improves the sound and feel of the golf club head at impact and only minimally reduces performance of the golf club head. For example, the one or more cutouts and/or other relief maintains face flexibility, characteristic time (CT) and coefficient of restitution (COR) of the striking face.

Abstract: Methods, devices, apparatuses and systems are disclosed for performing mammography, such as utilizing tomosynthesis in combination with breast biopsy.