Patents by Inventor John Mendelsohn

John Mendelsohn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EGF RECEPTOR MIMICKING PEPTIDES
    Publication number: 20130059793
    Abstract: Provided are peptides which can mimic the epidermal growth factor receptor (EGFR), e.g., by selectively binding TGF-? and/or EGF. In certain embodiments, the peptides are retro-inverted peptides. The peptides may be used as soluble decoys for TGF-? and/or EGF, and anti-cancer properties of peptides are demonstrated both in vitro and in vivo. The peptides may be administered alone or comprised in a fusion construct, imaging construct, and/or a therapeutic construct, e.g., for the treatment of a cancer.
    Type: Application
    Filed: February 8, 2011
    Publication date: March 7, 2013
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Marina Cardó-Vila, Ricardo J. Giordano, John Mendelsohn, Wadih Arap, Renata Pasqualini
  • Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
    Patent number: 4943533
    Abstract: Hybrid cell lines that synthesize and secrete monoclonal antibodies against epidermal growth factor receptor generated by the fusion of myeloma cells to lymphocytes immunized with epidermal growth factor receptor are disclosed. The method of generating the hybridomas, as well as therapeutic and diagnostic uses of the monoclonal antibodies in both cancer treatment and research are also disclosed.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: July 24, 1990
    Assignee: The Regents of the University of California
    Inventors: John Mendelsohn, Tomoyuki Kawamoto, Gordon Sato, J. Denry Sato