Abstract: A system, including a body worn and/or implanted medical device, wherein the medical device is configured to receive and store data indicative of past treatment of a person who is the wearer and/or has been implanted with the medical device, and the medical device is configured to at least one of provide tissue stimulation to tissue of the person or sense phenomenon associated with the person.

Abstract: The subject matter of the present disclosure generally relates to techniques for following a treatment protocol having one or more treatment parameters to cause a targeted physiological outcome at a distal site, assessing an expression level of a gene in a region of interest after completing the treatment protocol, and modifying the one or more treatment parameters based on the expression level of the gene. The treatment protocol may include one or more ultrasound energy treatments to the region of interest.

Abstract: A packaging material including one or more expandable layers that provide protection to contents of a packaging enclosure formed with the packaging material. The packaging material includes at least a first layer and a second layer bonded to one another. The first layer is pulled or extended in a first direction that is effective to cause the second layer to expand in a second direction. The second layer is a cut-patterned layer which increases in thickness and provides structural strength to the packaging material when expanded.

Abstract: An ophthalmically compatible solution includes (a) about 0.005 to about 2 wt. %, based on the total weight of the ophthalmically compatible solution, of hyaluronic acid or a salt thereof; (b) about 0.01 to about 1 wt. %, based on the total weight of the ophthalmically compatible solution, of erythritol; (c) sodium chloride, potassium chloride or any combination thereof; and (d) one or more buffers.

Abstract: Systems and methods are provided for storing excess heat from subsea flowlines. The methods described herein may include generating power from a renewable energy source; heating one or more heater cables surrounding a subsea flowline with the power from the renewable energy source to a temperature at least a threshold above a temperature necessary to prevent hydrate or wax formation within the subsea flowline; storing excess heat generated by the one or more heater cables in the seafloor; and decreasing a heat loss of the subsea flowline with the excess heat generated by the one or more heater cables when the power from the renewable energy source is insufficient to heat the one or more heater cables to the temperature necessary to prevent hydrate or wax formation within the subsea flowline.

Abstract: A docking station for a prosthetic implant includes a frame. The frame includes one or more tissue engaging elements, which is some examples are apices of the frame formed by struts of the frame. The frame and/or the apices can be configured to engage native tissue at an implantation location to retain the position of the frame without damaging the native tissue. A docking station can also include a sealing skirt and/or a protective cover coupled to the frame. The sealing skirt can reduce retrograde blood flow through and/or around the frame. The protective cover can reduce damage to the native tissue.

Abstract: A patient transport apparatus operable by a user for transporting a patient along stairs. A seat section is coupled to a support structure. A track having a belt is attached to the support structure and is arranged for selective operation between: a retracted position, and a deployed position to engage stairs. A drive system with a motor is disposed in rotational communication with the belt to control movement along stairs in the deployed position. A user interface us arranged for engagement to selectively adjust operation of the drive system between: an active state for controlling movement of the belt with the motor, and an inactive state. A braking controller is configured to sense movement of the belt in the inactive state, and to control the motor to limit movement of the belt in the inactive state to effect corresponding limited movement of the patient transport apparatus along stairs.

Abstract: In a flip-chip LED assembly having an array of LEDs formed on the same substrate, different LEDs of the array have different distances to the n-contacts of the assembly. This may cause current crowding as current has to spread from the n-contacts through the substrate to each the farthest LEDs of the LED array, requiring LEDs that are farther away to be driven with a higher voltage in order to receive a desired amount of current. To spread current more evenly through the LED assembly and reduce a voltage difference between the closest and farthest LEDs of the array, a current spreading layer having a conductive material (e.g., a conductive oxide) is formed on a surface of the substrate of the LED assembly. The current spreading layer may be a bulk layer or be patterned to increase light extraction from the LEDs of the array.

Abstract: A surgical manipulator and method of operating the same. The surgical manipulator includes an arm with a plurality of links and joints, wherein an angle between adjacent links forms a joint angle. The arm includes a distal end configured to support a surgical instrument with an energy applicator. At least one controller is coupled to the arm and models the surgical instrument and the energy applicator as a virtual rigid body. The controller(s) determine a commanded pose for the surgical instrument and the energy applicator based on a summation of a plurality of forces and/or torques, wherein the plurality of forces and/or torques are selectively applied to the virtual rigid body to emulate orientation and movement of the surgical instrument and the energy applicator. The controller(s) determine commanded joint angles for the arm that place the surgical instrument and the energy applicator according to the commanded pose.

Abstract: Through a workflow interface, a document management system enables a user to establish a document workflow. The document workflow establishes a set of document actions for the document management system to perform automatically in response to a request from the user. The user defines the document workflow by selecting from a set of workflow operations and specifying parameters for the selected workflow operation. The user additionally defines an approval workflow operation and a rejection workflow operation that designate document actions in the event that a document is approved or rejected, respectively. The document management system performs at least a portion of the document workflow in an order determined from the workflow interface.

Abstract: Systems and methods are provided for modeling call center networks. Models are employed to run a simulation of the call center network based on call center network architecture data. The models are used to generate solution parameters for a call center network, and the solution parameters can be automatically implemented in at least a portion of the call center network.

Abstract: A session data processing network includes a POS terminal and at least one computer server. The POS terminal is configured to establish a secure communications session with a communications appliance, receive session data from the communications appliance via the communications session, extract a ledger identifier and a token from the session data, transmit an authorization request message and a rewards request message to the server. The authorization request message includes the ledger identifier and an authorization value. The rewards request message includes the token and requests a reward of loyalty points to a secondary ledger associated with the token. The server is configured to receive the authorization request message and the loyalty rewards request message, confirm authorization of a transaction in an amount equal to the authorization value from an account associated with the ledger identifier, and transmit to the POS terminal an authorization response message confirming the authorization.

Abstract: A method of manufacturing a fibrous water soluble product having particles, including: a) providing a first continuous water soluble fibrous substrate including a first side and moving in a first direction, b) providing a discretizing unit including one or more pockets comprising an opening; c) providing a continuous feed of first particles to at least one of the one or more pockets of the discretizing unit through the pocket opening at least partially filling the at least one of the one or more pockets, d) delivering the first particles from the pocket through the opening onto a portion of the first side of the first continuous water soluble fibrous substrate, and e) at least partially covering the first side of the first continuous water soluble fibrous substrate.

Abstract: A packaging material including one or more expandable layers that provide protection to contents of a packaging enclosure formed with the packaging material. The packaging material includes at least a first layer and a second layer bonded to one another. The first layer is pulled or extended in a first direction that is effective to cause the second layer to expand in a second direction. The second layer is a cut-patterned layer which increases in thickness and provides structural strength to the packaging material when expanded.

Abstract: A packaging material including one or more expandable layers that provide protection to contents of a packaging enclosure formed with the packaging material. The packaging material includes at least a first layer and a second layer bonded to one another. The first layer is pulled or extended in a first direction that is effective to cause the second layer to expand in a second direction. The second layer is a cut-patterned layer which creates structural strength in the packaging material when expanded.

Abstract: The present disclosure provides methods of increasing the activity of regulatory T cells (Tregs), e.g., to treat autoimmune or inflammatory diseases or disorders, using antagonist, nondepleting antibodies and antigen-binding fragments thereof that specifically bind to OX40 (e.g., human OX40).

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

Abstract: A method including while receiving a live digital audio stream from one or more remote servers and outputting the live digital audio stream via a speaker of a client device, receiving the updated content schedule from the one or more remote servers, generating and displaying a real-time programming guide user-interface including the updated content schedule and least one content segment component corresponding to at least one of the content segment data in the updated content schedule. The method further includes transmitting a content segment digital audio signal request to the one or more remote servers for a prior portion of the live digital audio stream corresponding to the content segment data; and, in response to receiving the prior portion of the live digital audio stream, ceasing outputting the live digital audio stream and outputting the prior portion of the live digital audio stream corresponding to the content segment data.

Abstract: A packaging material including one or more expandable layers that provide protection to contents of a packaging enclosure formed with the packaging material. The packaging material includes at least a first layer and a second layer bonded to one another. The first layer is pulled or extended in a first direction that is effective to cause the second layer to expand in a second direction. The second layer is a cut-patterned layer which increases in thickness and provides structural strength to the packaging material when expanded.