Abstract: An audio system for user hearing assessment includes one or more audio capture devices, and processing circuitry. The one or more audio capture devices are configured to capture audio of a conversation of a user and convert the audio to audio signals. The processing circuitry is configured to use the audio signals to identify multiple conditions associated with user hearing difficulty. The conditions include any of words, phrases, frequencies, or phonemes, and environmental audio conditions that are followed by an indication of user hearing difficulty. The processing circuitry is configured to generate a hearing profile for the user based on the identified conditions associated with user hearing difficulty. The processing circuitry is configured to adjust an operation of an audio output device using the hearing profile to reduce a frequency of user hearing difficulty if the user requires audio enhancement.

Abstract: An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk.

Abstract: A dual deflection ring system includes a pair of components that rotate relative to one another about an axis of rotation. One or more deflection rings are disposed between the components. The deflection ring(s) include two sets of pockets configured to provide two levels of compressibility in-series between the components. The two sets of pockets project radially relative to the axis of rotation and are compressible between the components.

Abstract: The present disclosure generally relates to displaying a user interface for sharing an account associated with a first user identity with a second user identity. The user interface includes a first sharing option and a second sharing option. One or more inputs corresponding to a request to share the account are detected. If the one or more inputs include a selection of the first sharing option, a request to invite the second user identity to become a joint owner of the account is transmitted. If the one or more inputs include a selection of the second sharing option, a request to invite the second user identity to become a participant of the account without becoming a joint owner of the account is transmitted.

Abstract: The disclosed computer-implemented method may include applying, via a sound reproduction system, sound cancellation that reduces an amplitude of various sound signals. The method further includes identifying, among the sound signals, an external sound whose amplitude is to be reduced by the sound cancellation. The method then includes analyzing the identified external sound to determine whether the identified external sound is to be made audible to a user and, upon determining that the external sound is to be made audible to the user, the method includes modifying the sound cancellation so that the identified external sound is made audible to the user. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts, solvates and prodrugs thereof: wherein Q is selected from O, S and Se; J is S or Se; W1 and W2, when present, are independently selected from N and C; R1 and R2 are independently selected from the group consisting of hydrogen, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, heterocyclyl, heteroaryl, cycloalkyl, cycloalkenyl, amino, amido, alkylthio, acyl, arylalkyl and acylamido, all of which may be optionally substituted; and wherein at least one of W1 and W2 is present and is a nitrogen atom and when R1 or R2 are cyclic then the respective W1 or W2 may form part of the ring structure. The present invention also relates to pharmaceutical compositions including such compounds, to methods of treatment using such compounds, in particular in relation to NLRP3 inflammasome mediated disorders, and to associated diagnostic uses.

Abstract: The present disclosure generally relates to a computer system displaying user interfaces for accessing passes and transfer accounts. In some examples, passes are added to the computer system. In some examples, passes are accessed. In some examples, transfers relating to the passes and transfer accounts are displayed, such as in search user interfaces.

Abstract: A magnetic inductive resonance charging circuit includes a resonant network having an inductive secondary coil that converts a magnetic field received from an inductive primary coil into an alternating current (AC) signal and a synchronous rectifier that rectifies the AC signal to generate a direct current (DC) signal for application to a load. The synchronous rectifier includes a variety of configurations for shunting the AC waveform of an AC current source in the event of a fault. For example, a rectifier controller may hold a pair of normally open switches of the rectifier off and a pair of normally closed switches of the rectifier on to shunt the AC current source when an over-voltage, over-current fault condition or an over-temperature fault condition is detected. Configurations are provided for grounding the capacitive electromagnetic interference produced in the chassis of an electric vehicle when the resonant network is unbalanced.

Abstract: The present invention relates to compounds of formula (I): wherein Q is O or S; R1 is a cyclic group substituted with at least one group X, wherein R1 may optionally be further substituted; X is any group comprising a carbonyl group; and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the dual action of NLRP3 inhibition and the stimulation of insulin secretion.

Abstract: A robotic procedure system for treating neurovasculature of a patient including a guide sheath, catheter system having a support catheter and a navigation catheter, and robotic drive system configured to drive the catheter system within a patient's vessel. The robotic drive system includes a cassette with at least a first set of rollers and at least a second set of rollers and a controller operatively coupled to the cassette. The first set of rollers is configured to engage a proximal control element of the support catheter and the second set of rollers configured to engage a proximal extension of the navigation catheter. The controller is configured to control the first set and second set of rollers so as to determine a magnitude of linear translation of the support catheter and a magnitude of linear translation of the navigation catheter. Related devices, systems, and methods are provided.

Abstract: A database is stored as a plurality of database shards in a distributed database grid comprising a plurality of grid elements, each including a mid-tier database system. A first grid element receives, from an application executing in the same memory as a mid-tier database system of the first grid element, a first database transaction including at least one database operation on specific data stored in a first database shard that belongs to the first grid element. The first grid element performs and commits the first database transaction without participation of another grid element of the plurality of grid elements. The first grid element receives a second database transaction that requires access to another database shard that does not belong to the first grid element. Multiple grid elements of the plurality of grid elements perform the second database transaction and commit the second database transaction using a two-phase commit protocol.

Abstract: Disclosed herein is a methodology which quickly provides for the analysis of multiple luminescence decays from individual phosphor samples. The disclosed method utilizes a Trust-Region method to provide non-physical solutions when the fitting application was not provided with bounds for the respective intensities and decay times. Results from Double Decay were found to be statistically similar to data analyzed in methodologies known in the art.

Abstract: Methods of treating intracranial atherosclerotic disease carotid atherosclerosis, and intracranial and cerebral aneurysms by deploying implantable expandable devices. A catheter system is advanced through a base sheath towards an intracranial vessel having an atherosclerotic lesion. A tapered end region of an inner catheter is positioned distal to a distal end of an outer catheter, at least a portion of the tapered end region of the inner catheter crosses the lesion. The outer catheter is advanced over the inner catheter across the lesion. The inner catheter is withdrawn while the outer catheter is maintained in place. A stent delivery system is advanced through the catheter lumen. The outer catheter is withdrawn to unsleeve the stent and the stent delivery system maintained in place. The stent is deployed against the lesion. Related devices, systems, and methods are provided.

Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, the system may include a device (e.g., an implantable pulse generator) and an electrode device electrically coupled to the device. In some examples, the device may be configured to generate a current that is to be applied to the anatomical element via the electrode device to stimulate the anatomical element as part of a therapy aimed at achieving or supporting glycemic control in the patient. Additionally, the current may be applied to the anatomical element based on a machine learning algorithm that uses inputs gathered for determining one or more characteristics for the current. Accordingly, the machine learning algorithm may be configured to determine the one or more characteristics for the current specific to the patient (e.g., to provide personalized therapy settings for the patient).

Abstract: A system is described that includes: a first sensor that measures a glycemic level of a patient; a second sensor that measures at least one of a protein level of the patient, a hormone level of the patient, and an activity level of the patient; a processor that receives inputs from the first sensor and inputs from the second sensor; and memory including data that, when executed by the processor, enables the processor to perform one or more functions. An example of such function(s) include: analyzing the inputs received from the first sensor and the second sensor; determining, based on the analysis, that an electrical treatment is to be applied to the patient, where the electrical treatment includes application of at least one electrical signal to a nervous system of the patient; and causing the electrical treatment to be applied to the nervous system of the patient.

Abstract: A system is provided herein for stimulating an anatomical element of a patient to regulate insulin production of the patient. In some examples, the system may include a device configured to generate a current and an electrode device electrically coupled to the device. Subsequently, the device may receive instructions to apply the current to the anatomical element via a plurality of electrodes of the electrode device, where the current is configured to regulate insulin production of the patient. For example, a first electrode may be configured for placement on or around a celiac vagal trunk, where the current downregulates neural activity of the celiac vagal trunk, and a second electrode may be configured for placement on or around a hepatic vagal trunk, where the current upregulates neural activity of the hepatic vagal trunk.

Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, a device may be configured to generate a current, and an electrode device coupled to the device may be configured to apply the current to the anatomical element. In some examples, the current may be configured to prevent hypoglycemic episodes from occurring in the patient when applied to the anatomical element. For example, the current may be configured to downregulate neural activity of a celiac vagal trunk and to upregulate neural activity of a hepatic vagal trunk. Accordingly, the current being applied to anatomical element of the patient may result in a decrease in insulin production of the patient, an increase in glucose production of the patient, an increase in blood sugar levels of the patient, or a combination thereof. Additionally, applying the current may prevent nocturnal hypoglycemic episodes from occurring.

Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, a device may be configured to generate a current, and an electrode device coupled to the device may be configured to apply the current to the anatomical element. Additionally, the system may include a user interface in communication with the implantable pulse generator, the electrode device, or both. In some examples, the user interface may include a first element that is configured to display information associated with the patient. Additionally, the user interface may include a second element that is configured to receive inputs for programming parameters of the current. The user interface may also include a third element that is configured to display diagnostic information associated with applying the current to the anatomical element.

Abstract: Systems and methods for mechanically blocking a nerve are provided. The system may comprise a blocking device configured to selectively compress the nerve. The system may also comprise a feedback mechanism configured to measure a response correlating to whether the nerve is blocked. When the blocking device compresses the nerve, a response from the feedback mechanism is received that correlates to the nerve being blocked or unblocked after a period of time.