Patents by Inventor John Moorhouse
John Moorhouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8420754Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: GrantFiled: November 11, 2010Date of Patent: April 16, 2013Assignee: Univation Technologies, LLCInventors: Kevin J Cann, Minghui Zhang, Jose Fernando Cevallos-Candau, John Moorhouse, Mark Gregory Goode, Daniel Paul Zilker, Jr., Maria Apecetche
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Patent number: 8142994Abstract: The present invention relates to methods of genetic analysis for the classification, diagnosis and prognosis of acute myeloid leukemia (AML). The invention provides a method for producing a classification scheme for AML comprising the steps of a) providing a plurality of reference samples, the reference samples comprising cell samples from a plurality of reference subjects affected by AML; b) providing reference profiles by establishing a gene expression profile for each of the reference samples individually; c) clustering the individual reference profiles according to similarity; and d) assigning an AML class to each cluster. The invention further relates to a method for classifying the AML of an AML-affected subject, to a method for diagnosing AML in a subject, and to a method of determining the prognosis for an AML-affected subject.Type: GrantFiled: February 23, 2005Date of Patent: March 27, 2012Assignee: Erasmus University Medical Center RotterdamInventors: Michael John Moorhouse, Petrus Jacobus Maria Valk, Hendrik Rudolf Delwel, Bob Lowenberg, Petrus Johannes van der Spek
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Publication number: 20110060111Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: ApplicationFiled: November 11, 2010Publication date: March 10, 2011Applicant: UNIVATION TECHNOLOGIES, LLCInventors: Kevin J. Cann, Minghui Zhang, Jose Fernando Cevallos-Candau, John Moorhouse, Mark Gregory Goode, Daniel Paul Zilker, JR., Maria Apecetche
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Patent number: 7816296Abstract: Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition.Type: GrantFiled: January 20, 2010Date of Patent: October 19, 2010Assignee: Univation Technologies, LLCInventors: Maria A. Apecetche, John Moorhouse, Mark G. Goode, Ronald S. Eisinger, Kevin J. Cann
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Publication number: 20100137533Abstract: Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition.Type: ApplicationFiled: January 20, 2010Publication date: June 3, 2010Applicant: Univation Technologies, LLCInventors: Maria A. Apecetche, John Moorhouse, Mark G. Goode, Ronald S. Eisinger, Kevin J. Cann
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Patent number: 7563851Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: GrantFiled: August 11, 2005Date of Patent: July 21, 2009Assignee: Univation Technologies, LLCInventors: Kevin J Cann, Minghui Zhang, Jose Fernando Cevallos-Candau, John Moorhouse, Mark Gregory Goode, Daniel Paul Zilker, Jr., Maria Apecetche
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Patent number: 7504463Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: GrantFiled: August 11, 2005Date of Patent: March 17, 2009Assignee: Univation Technologies, LLCInventors: Kevin J Cann, Minghui Zhang, Jose Fernando Cevallos-Candau, John Moorhouse, Mark Gregory Goode, Daniel Paul Zilker, Jr., Maria Apecetche
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Publication number: 20080305965Abstract: The present invention relates to method of genetic analysis for the classification, diagnosis and prognosis of acute myeloid leukemia (AML). The invention provides a method for producing a classification scheme for AML comprising the steps of a) providing a plurality of reference samples, said reference samples comprising cell samples from a plurality of reference subjects affected by AML; b) providing reference profiles by establishing a gene expression profile for each of said reference samples individually; c) clustering said individual reference profiles according to similarity; and d) assigning an AML class to each cluster. The invention further relates to a method for classifying the AML of an AML affected subject, to a method for diagnosing AML in a subject, and to a method of determining the prognosis for an AML affected subject.Type: ApplicationFiled: February 23, 2005Publication date: December 11, 2008Applicant: ERASMUS UNIVERSITEIT ROTTERDAMInventors: Michael John Moorhouse, Petrus Jaobus Maria Valk, Hendrik Rudolf Delwell, Bob Lowenberg, Petrus Johannes van der Spek
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Publication number: 20080242821Abstract: Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition.Type: ApplicationFiled: June 4, 2008Publication date: October 2, 2008Applicant: UNIVATION TECHNOLOGIES, LLCInventors: Maria A. Apecetche, John Moorhouse, Mark G. Goode, Ronald S. Eisinger, Kevin J. Cann
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Patent number: 7414099Abstract: Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition.Type: GrantFiled: October 13, 2005Date of Patent: August 19, 2008Assignee: Univation Technologies, LLCInventors: Maria A. Apecetche, John Moorhouse, Mark G. Goode, Ronald S. Eisinger, Kevin J. Cann
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Publication number: 20080090976Abstract: Broad molecular weight polyethylene and polyethylene having a bimodal molecular weight profile can be produced with chromium oxide based catalyst systems employing alkyl silanols. The systems may also contain various organoaluminum compounds. Catalyst activity and molecular weight of the resulting polyethylene may also be tuned using the present invention.Type: ApplicationFiled: December 5, 2007Publication date: April 17, 2008Applicant: UNIVATION TEHNOLOGIES, LLCInventors: Kevin Cann, Minghui Zhang, John Moorhouse, Maria Apecetche
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Publication number: 20060237522Abstract: An optical security system having a key, an optic lock, and a processing system. The lock generally has a plurality of optic reflective sensors, a plurality of rotatable readable discs, and a controller for processing information to and from the plurality of sensors. The optic security lock senses the surface changes of state during the rotation of the plurality of discs caused by the turning of the fully-engaged key. The data from the sensors is communicated to the controller, with the controller having a processor capable of processing data from the sensors to generate a lock command signal. The lock can include a plurality of detent mechanisms to provide precision interval alignment of the sensors with the rotatable discs to accurately sense the surface changes of state.Type: ApplicationFiled: May 19, 2006Publication date: October 26, 2006Inventors: John Moorhouse, Michael Bodin, Kurt Larsen, Donald Stauffenecker
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Publication number: 20060183630Abstract: Broad molecular weight polyethylene and polyethylene having a bimodal molecular weight profile can be produced with chromium oxide based catalyst systems employing alkyl silanols. The systems may also contain various organoaluminum compounds. Catalyst activity and molecular weight of the resulting polyethylene may also be tuned using the present invention.Type: ApplicationFiled: January 31, 2006Publication date: August 17, 2006Inventors: Kevin Cann, Minghui Zhang, John Moorhouse, Maria Apecetche
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Publication number: 20060128908Abstract: Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition.Type: ApplicationFiled: October 13, 2005Publication date: June 15, 2006Inventors: Maria Apecetche, John Moorhouse, Mark Goode, Ronald Eisinger, Kevin Cann
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Publication number: 20060074205Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: ApplicationFiled: August 11, 2005Publication date: April 6, 2006Inventors: Kevin Cann, Minghui Zhang, Jose Cevallos-Candau, John Moorhouse, Mark Goode, Daniel Zilker, Maria Apecetche
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Patent number: 6989344Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: GrantFiled: November 18, 2003Date of Patent: January 24, 2006Assignee: Univation Technologies, LLCInventors: Kevin J. Cann, Minghui Zhang, Jose Fernando Cevallos-Candau, John Moorhouse, Mark Gregory Goode, Daniel Paul Zilker, Jr., Maria Apecetche
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Publication number: 20050272886Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: ApplicationFiled: August 11, 2005Publication date: December 8, 2005Inventors: Kevin Cann, Minghui Zhang, Jose Cevallos-Candau, John Moorhouse, Mark Goode, Daniel Zilker, Maria Apecetche
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Publication number: 20050205657Abstract: An optical security system having a key, an optic lock, and a processing system. The lock generally has a plurality of optic reflective sensors, a plurality of rotatable readable discs, and a controller for processing information to and from the plurality of sensors. The optic security lock senses the surface changes of state during the rotation of the plurality of discs caused by the turning of the fully-engaged key. The data from the sensors is communicated to the controller, with the controller having a processor capable of processing data from the sensors to generate a lock command signal. The lock can include a plurality of detent mechanisms to provide precision interval alignment of the sensors with the rotatable discs to accurately sense the surface changes of state.Type: ApplicationFiled: March 1, 2005Publication date: September 22, 2005Inventors: John Moorhouse, Michael Bodin, Kurt Larsen, Donald Stauffenecker
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Publication number: 20050037917Abstract: The present invention is directed to the use of aluminum alkyl activators and co-catalysts to improve the performance of chromium-based catalysts. The aluminum alkyls allow for the variable control of polymer molecular weight, control of side branching while possessing desirable productivities, and may be applied to the catalyst directly or separately to the reactor. Adding the alkyl aluminum compound directly to the reactor (in-situ) eliminates induction times.Type: ApplicationFiled: November 18, 2003Publication date: February 17, 2005Inventors: Kevin Cann, Minghui Zhang, Jose Cevallos-Candau, John Moorhouse, Mark Goode, Daniel Zilker, Maria Apecetche