Patents by Inventor John Morgan Hardham

John Morgan Hardham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Vaccine Compositions for Porcine Epidemic Diarrhea Virus and Porcine Deltacoronavirus
    Publication number: 20170202951
    Abstract: The present invention is directed to novel immunogenic compositions that protect swine from disease caused by porcine epidemic diarrhea virus (PEDV). The present invention is also directed to novel immunogenic compositions that protect swine from disease caused by porcine deltacoronavirus (PDCoV), alone or as combination vaccine to protect against PEDV. The compositions of the invention provide killed viruses whose effectiveness is enhanced by the selection of preferred adjuvants. Novel culture methods are also employed to increase reproducible yield of cultured viruses. Live vaccines are also provided from the Calaf14 PEDV isolate.
    Type: Application
    Filed: July 8, 2015
    Publication date: July 20, 2017
    Inventors: Jacqueline Gayle MARX, John Morgan Hardham, Paul J. Dominowski, Vicki Jon Rielson, Monica Sanuy Balasch, Marta Cabana Sumsi, Laia Plaja Dilmé, Alicia URNIZA Hostench, Oscar Romero Galindo
  • OIL-BASED ADJUVANTS
    Publication number: 20150140034
    Abstract: The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.
    Type: Application
    Filed: September 19, 2014
    Publication date: May 21, 2015
    Inventors: Paul Joseph Dominowski, Dennis L. Foss, Guillermo Gallo, John Morgan Hardham, Richard Lee Krebs, Sandra Ann Marie Lightle, Suman Mahan, Sangita Mediratta, Kaori Mohr, Duncan Mwangi, Sharath K. Rai, Sarah A. Salmon, Shaunak Vora, Lauren Wilmes
  • Vaccine for periodontal disease
    Patent number: 7468185
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: December 23, 2008
    Assignee: Pfizer Inc.
    Inventors: John Morgan Hardham, Kendall Wayne King, Rajendra Krishnan, Kimberly Jean Dreier, David Ross McGavin
  • Vaccine For Periodontal Disease
    Publication number: 20080311151
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.
    Type: Application
    Filed: May 12, 2008
    Publication date: December 18, 2008
    Applicants: PFIZER, INC., PFIZER PRODUCTS, INC.
    Inventors: John Morgan Hardham, Kendall Wayne King, Rajendra Krishnan, Kimberly Jean Dreier, David Ross McGavin, John David Haworth
  • Vaccine for periodontal disease
    Patent number: 7378101
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: May 27, 2008
    Assignees: Pfizer, Inc., Pfizer Products, Inc.
    Inventors: John Morgan Hardham, Kendall Wayne King, Rajendra Krishnan, Kimberly Jean Dreier, David Ross McGavin, John David Haworth
  • Vaccine for periodontal disease
    Publication number: 20030228328
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease.
    Type: Application
    Filed: December 18, 2002
    Publication date: December 11, 2003
    Applicant: Pfizer Inc.
    Inventors: John Morgan Hardham, Kendall Wayne King, Rajendra Krishnan, Kimberly J. Dreier, David R. McGavin