Abstract: A system including a communication interface to communicatively couple to a sensor cartridge, a fluidic subsystem to exchange a reagent solution with the sensor cartridge, and a computational circuitry communicatively coupled to the communication interface and the fluidic subsystem. The computation circuitry is to monitor a sensor signal of a sensor of the sensor cartridge, detect a leak based on the sensor signal, and control fluid flow of the fluidic subsystem in response to detecting.

Abstract: An apparatus for detecting chemical reactions may be provided. The apparatus may comprise a chemical detection device. The chemical detection device may include a chemical sensor, which may be mounted on the chemical detection device. The apparatus may further comprise a valve block. The valve block may fluidly couple a plurality of reagent containers to the chemical detection device. The apparatus may further comprise a heat exchanger and a controller. The controller may control a fluid connection between the valve block and the chemical detection device. The controller may be also configured to adjust a temperature of a selected reagent from the plurality of reagent containers via the heat exchanger. The temperature of the selected reagent may be adjusted prior to the reagent entering the chemical detection device.

Abstract: A leak resistant electrical connector configured as a fluidic barrier between a fluidics device, which may comprise a chemFET sensor, and other electrical circuitry wherein the fluidics device further comprises one or more electrical contacts conductively coupled to one or more electrical contacts associated with the electrical circuitry through the connector.

Abstract: The invention is directed to apparatus and methods for delivering multiple reagents to, and monitoring, a plurality of analytical reactions carried out on a large-scale array of electronic sensors underminimal noise conditions. In one aspect, the invention provides method of improving signal-to-noise ratios of output signals from the electronic sensors sensing analytes or reaction byproducts by subtracting an average of output signals measured from neighboring sensors where analyte or reaction byproducts are absent. In other aspects, the invention provides an array of electronic sensors integrated with a microwell array for confining analytes and/or particles for analytical reactions and a method for identifying microwells containing analytes and/or particles by passing a sensor-active reagent over the array and correlating sensor response times to the presence or absence of analytes or particles.

Abstract: The invention relates to a thin film coated array and the process of fabricating and using the array including methods of etching, depositing a thin film coating, preparing and using the thin film coated array.

Abstract: This invention relates to microwell array compositions which are coated with one or more thin film coatings. The invention includes the process of fabricating and using thin film coated microwell arrays.

Abstract: An improved heat exchanger design is disclosed. The design of the heat exchanger provides for a safe separation of the flow streams even in the event of leakage. An improved heat recovery device for use in the drain conduit of standard shower installations, comprising the heat exchanger of the invention, is also disclosed.

Abstract: The invention relates to a thin film coated array and the process of fabricating and using the array including methods of etching, depositing a thin film coating, preparing and using the thin film coated array.

Abstract: This invention relates to microwell array compositions which are coated with one or more thin film coatings. The invention includes the process of fabricating and using thin film coated microwell arrays.

Abstract: Embodiments of the present invention are directed to methods and devices/systems for amplifying genetic material and may include providing a water-in-oil emulsion in a continuous flow. The emulsion may include a plurality of water droplets comprising microreactors. Each of the plurality of microreactors may include a single bead capable of capturing a nucleic acid template, a single species nucleic acid template and sufficient reagents to amplify the copy number of the nucleic acid template. The method also includes flowing the emulsion across a first temperature zone and a second lower temperature zone to thermally process the microreactors to amplify the nucleic acid template by polymerase chain reaction.

Abstract: A tape dispensing apparatus comprising a frame, and a tape marking assembly. The frame has a tape supply section for holding a tape supply therein, and a tape dispensing opening for dispensing tape from the apparatus. The tape marking assembly is connected to the frame for marking the tape dispensed from the tape dispensing opening of the apparatus. The tape marking assembly is pivotably mounted to the frame for pivoting relative to the frame between an operating position, and a non-operating position of the tape marking assembly. The tape marking assembly includes at least one control arm extending between the tape marking assembly and the frame. The at least one control arm is spring loaded for biasing the tape marking assembly towards the operating position of the assembly. The at least one control arm bias on the tape marking assembly increases as the assembly is pivoted towards the operating position.

Abstract: A tape dispensing apparatus comprising a frame and at least one tape creasing part. The frame has a tape supply section for holding a tape supply therein, and a tape dispensing opening for dispensing tape from the apparatus. The tape creasing part is connected to the frame for creasing tape dispensed from the tape dispensing opening and forming a self-supporting tape section extending from the tape dispensing apparatus substantially without droop.

Abstract: In a mailpiece stacking system, a pressure pad is used to direct incoming mailpieces from a mailing machine used with the system onto a feed deck, where the mailpieces are stacked against a stacking wall in the system. To properly handle mailpieces including window envelopes, the length of the pressure pad is selected in accordance with the invention such that it effectively deflects each mailpiece to land beyond the window part of any window envelope preceding thereto on the feed deck. Advantageously, the risk of having the mailpiece getting caught by an edge of the window part, resulting in a congestion, is avoided. In addition, among other things, a catch nub is included in the pressure pad for hooking onto a stub shaft mounted on the frame of the system. The nub hooks onto the stub shaft when the pressure pad is raised to allow it to stay in the raised position.

Abstract: A mail piece stacking machine is disclosed which is designed for use on conjunction with a mail piece processing or handling machine, such as a typical mailing machine, for stacking a plurality of pieces of mail as they are ejected seriatim from an outlet end of the processing or handling machine. The stacking machine has an elongate frame with a first feeding device consisting of a pair of cooperating rollers disposed adjacent the inlet end of the stacking machine, receives the mail pieces seriatim from the processing or handling machine and positively feeds the mail pieces into the stacking machine.

Abstract: A bicycle fairing comprises a blunt molded body shield having a upstanding, rearwardly sloping, flexible, transparent windshield attached thereto. The body shield has a blunt end extending outwardly therefrom having an axis passing therethrough forming an angle with the rearwardly sloping windshield from a side elevation which is more than twice the angle of a rearwardly sloping lower surface of the shield. The body portion of the fairing above the axis in side elevation is approximately twice the length of the fairing extending below the axis. Accordingly, the windshield is high enough to shield the rider while the fairing extends downwardly enough to prevent airflow from coming up from the bottom onto the rider. The fairing is mounted at four fixed points at its extremeties for maximum rigidity and is easily adjustable and removable or can be permanently installed.