Abstract: The present disclosure generally relates to a biopsy needle configured to maximize tissue sampling yield and collect a unit of sampled tissue. The biopsy needle includes an elongate tubular body comprising a lumen extending therethrough from a proximal open end to a distal open end of the body. The distal end includes first and second tip portions extending therefrom and formed on opposing sides of the needle body. The first tip portion generally extends further from the distal end than the second tip portion, resembling a staggered configuration, resulting in an increased surface area of multiple cutting edges formed between the first and second tip portions on either side of the needle body. Additionally, each of the tip portion defines a penetrating point configured to pierce the tissue to be sampled and direct sampled tissue towards the lumen of the body to be excised by the cutting edges.

Abstract: Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. A stent delivery system may include a tubular member configured to advance through an access site and a primary constrainment member configured to releasably couple the stent to the tubular member. The stent delivery system may further include a secondary constrainment member at least partially disposed around the primary constrainment member, the stent, and the tubular member. In some cases, the tubular member and the primary constrainment member may be configured to reposition the stent within the body lumen after removal of the secondary constrainment member such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the primary constrainment member, and the secondary constrainment member from the body lumen through the access site.

Abstract: Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering the stent through an access site and deploying a distal portion of the stent from within an outer sheath. In some cases, the method may further include pushing a proximal portion of the stent from the outer sheath such that upon fully exiting the outer sheath, the proximal portion extends proximally to at least partially cover the access site with the stent. The system for delivering the stent into the body lumen may include a stent, a stent delivery apparatus, and an outer sheath. The system may further include an internal pusher configured to push a proximal portion of the stent from the outer sheath and axially compress the stent such that upon fully exiting the outer sheath, the proximal portion extends proximally to cover the access site.

Abstract: Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

Abstract: Methods, apparatuses and systems are described for delivering a stent through an access hole of a body lumen and covering up the access hole after deploying the stent. Stents are described that include a stent body defining a body lumen contact surface area and a deployable member configured to deploy from the stent body and increase the body lumen contact surface area of the stent. Deployable members that hinge, unroll, extend, expand, and coaxially translate with respect to the stent body are described. A system for delivering a stent into a body lumen are described that may include a coverage member configured to at least partially cover the hole in the wall of the stent upon withdrawing a tubular member through the hole in the wall of the stent. Coverage members may include a self-sealing membrane, a flap valve, or a hinged valve.

Abstract: Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. The method may include delivering the stent through an access site in a wall of the body lumen. In some cases, the method may include repositioning the stent within the body lumen to at least partially cover the access site with the stent. The stent may be repositioned within the body lumen by retracting the stent towards the access site such that a proximal portion of the stent at least partially covers the access site. The stent may then expand within the body lumen. In some cases, the stent may expand within the body lumen by releasing a primary constrainment member from the stent by pulling the primary constrainment member in a proximal direction away from the stent.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical. device.

Abstract: Methods, apparatuses and systems are described for implanting a plurality of fiducial markers into a tissue. Systems include a needle, a stylet sized to slide within a lumen of the needle, and a multi-stop stylet spacer having stopping features configured to engage with the stylet to stop the distal end of the stylet at one or more predetermined distances from the distal end of the needle. Methods for implanting a plurality of fiducial markers into a tissue are described and include inserting a needle preloaded with fiducial markers into a tissue, adjusting a multi-stop stylet spacer from a safety position to a first deployment position, deploying a first fiducial marker into the tissue, adjusting the stylet spacer from the first deployment position to a second deployment position, and deploying a second fiducial marker into the tissue.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.

Abstract: Methods, apparatuses and systems are described for implanting a plurality of fiducial markers into a tissue. Systems include a needle, a stylet sized to slide within a lumen of the needle, and a multi-stop stylet spacer having stopping features configured to engage with the stylet to stop the distal end of the stylet at one or more predetermined distances from the distal end of the needle. Methods for implanting a plurality of fiducial markers into a tissue are described and include inserting a needle preloaded with fiducial markers into a tissue, adjusting a multi-stop stylet spacer from a safety position to a first deployment position, deploying a first fiducial marker into the tissue, adjusting the stylet spacer from the first deployment position to a second deployment position, and deploying a second fiducial marker into the tissue.

Abstract: The reconstrainment band includes a hollow generally tubular shaped band having proximal and distal ends and having an exterior surface for engaging a stent and an interior surface for engaging a delivery tube. The exterior surface has at least one fin projecting therefrom along the longitudinal axis of the band. The fin has at least one obtusely shaped surface relative to the longitudinal axis and facing one of the ends. The reconstrainment band is included in a delivery device for intraluminally positioning and deploying a radially distensible stent. Reconstrainment of a partially deployed stent is provided by the delivery device.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.

Abstract: The reconstrainment band includes a hollow generally tubular shaped band having proximal and distal ends and having an exterior surface for engaging a stent and an interior surface for engaging a delivery tube. The exterior surface has at least one fin projecting therefrom along the longitudinal axis of the band. The fin has at least one obtusely shaped surface relative to the longitudinal axis and facing one of the ends. The reconstrainment band is included in a delivery device for intraluminally positioning and deploying a radially distensible stent. Reconstrainment of a partially deployed stent is provided by the delivery device.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.

Abstract: The present disclosure provides an adjustable delivery handle system for interchangeably delivering a needle to a biopsy site. The adjustable delivery handle system includes a delivery handle having an inner hub housing component configured to interchangeably receive a needle subassembly that can be inserted into and withdrawn from the proximal handle member. The needle subassembly includes a biopsy needle having a distinct tissue collection distal end configured to maximize tissue sampling yield and collect a cohesive unit of sampled tissue. The distal end of the needle includes first and second tip portions extending therefrom and radially opposing one another. The first tip portion has a length greater than the second tip portion, thereby resulting in an increased surface area of a curvilinear cutting edge extending from the first tip portion to the second tip portion.

Abstract: The present disclosure generally relates to a biopsy needle configured to maximize tissue sampling yield and collect a cohesive unit of sampled tissue. The biopsy needle includes an elongate tubular body comprising a lumen extending therethrough from a proximal open end to a distal open end of the body. The distal end includes first and second tip portions extending therefrom and radially opposing one another. The first tip portion has a length greater than the second tip portion, thereby resulting in an increased surface area of a curvilinear cutting edge extending from the first tip portion to the second tip portion. Additionally, each of the first and second tip portions defines a point configured to pierce the tissue to be sampled and further direct tissue towards the lumen of the body to be excised by the cutting edge upon contact therewith.

Abstract: Methods, apparatuses and systems are described for deploying a stent into a body lumen. A stent delivery system may include a sheath with a partially-tubular first portion made from a first material and a second portion made from a second material that is adhered to the first portion to form a tubular body. In some cases, the first material may be chemically incompatible with the second material such that the adhesion between the first portion and second portion is free from cross-linked bonds. The stent delivery system may further include a guidewire lumen with a distal tip that may be slidably disposed within the sheath and a tubular stent disposed between the guidewire lumen and an inside surface of the sheath. The sheath may be formed by coextruding the first material and the second material to form a striped tubular body of the sheath.

Abstract: A device for needle biopsy is provided. The device includes a handle member having proximal and distal portions. A proximal handle member is disposed to the proximal portion of the handle member and a distal handle member is disposed to the distal portion of the handle member. A sheath lumen is disposed within the handle member and extends from the distal portion of the handle member. A needle housing member is partially disposed to the proximal portion of the handle member and a needle is disposed within the sheath lumen. A plurality of protrusions are disposed upon the needle.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.

Abstract: The present disclosure generally relates to a biopsy needle configured to maximize tissue sampling yield and collect a unit of sampled tissue. The biopsy needle includes an elongate tubular body comprising a lumen extending therethrough from a proximal open end to a distal open end of the body. The distal end includes first and second tip portions extending therefrom and formed on opposing sides of the needle body. The first tip portion generally extends further from the distal end than the second tip portion, resembling a staggered configuration, resulting in an increased surface area of multiple cutting edges formed between the first and second tip portions on either side of the needle body. Additionally, each of the tip portion defines a penetrating point configured to pierce the tissue to be sampled and direct sampled tissue towards the lumen of the body to be excised by the cutting edges.