Patents by Inventor John P. O'Donnell

John P. O'Donnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120249588
    Abstract: Datacenter datasets and other information are visually displayed in an augmented reality view using a portable device. The visual display of this information is presented along with a visual display of the actual datacenter environment. The combination of these two displays allows installers and technicians to view instructions or other data that are visually correlated to the environment in which they are working.
    Type: Application
    Filed: March 21, 2012
    Publication date: October 4, 2012
    Applicant: PANDUIT CORP.
    Inventors: Jack D. Tison, Zachary J. Smolinski, John P. O'Donnell, Brendan F. Doorhy
  • Publication number: 20110065783
    Abstract: Hydroxylated nebivolol metabolites increase NO release from human endothelial cell preparations in a concentration dependent fashion following acute administration. In addition, hydroxylated nebivolol metabolites, including but not limited to 4-hydroxy-6,6?difluoro-, 4-hydroxy-5-phenol-6,6?difluoro-, and 4-hydroxy-8-pheno-6,6?difluoro-, have the ability to increase the capacity for NO release in human endothelial cells following chronic administration. This invention provides hydroxylated nebivolol metabolites and compositions comprising nebivolol and/or at least one hydroxylated metabolite of nebivolol and/or at least one additional compound used to treat cardiovascular diseases or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 20, 2010
    Publication date: March 17, 2011
    Inventors: John P. O'Donnell, Walter Owens, Joseph Duncan, Andrew Shaw, Jinn Wu
  • Patent number: 7838552
    Abstract: Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: November 23, 2010
    Assignee: Forest Laboratories Holdings Limited
    Inventors: Eric Davis, John P. O'Donnell, Peter Bruce Bottini, Andrew Shaw, R. Preston Mason
  • Patent number: 7795243
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: September 14, 2010
    Assignee: Pfizer, Inc.
    Inventors: Katherine E. Brighty, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
  • Patent number: 7795244
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: September 14, 2010
    Assignee: Pfizer Inc.
    Inventors: Katherine Elizabeth Brighty, Anthony Marfat, Dale M. McLeod, John P. O'Donnell
  • Publication number: 20090042853
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof preparation thereof formulation thereof and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Application
    Filed: June 30, 2008
    Publication date: February 12, 2009
    Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. Mcleod, John P. O'Donnell
  • Publication number: 20080161296
    Abstract: Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.
    Type: Application
    Filed: November 15, 2005
    Publication date: July 3, 2008
    Inventors: Eric Davis, John P. O'Donnell, Peter Bruce Bottini, Andrew Shaw, R. Preston Mason
  • Publication number: 20080125408
    Abstract: The invention relates to prodrugs of sulopenem of formula (I): wherein R1 is —(C2-C8)alkyl, or a solvate or hydrate thereof. The invention also relates to the preparation, formulation, and use of the prodrugs of sulopenem to treat a disorder such as an infection in a patient in need thereof.
    Type: Application
    Filed: November 13, 2007
    Publication date: May 29, 2008
    Inventors: Katherine Elizabeth Brighty, Anthony Marfat, Dale Gordon McLeod, John P. O'Donnell, Stephen R. Anderson
  • Publication number: 20080009474
    Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 10, 2008
    Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
  • Patent number: 6531449
    Abstract: The invention provides metabolites of the compound 2-amino-N-[2-(3a(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo-[4,3-c]pyridin-5-yl)-1-(R)-benzyl-oxymethyl-2-oxo-ethyl]-isobutyramide, the racemic-diastereomeric mixtures and optical isomers thereof, the prodrugs thereof, and the pharmaceutically acceptable salts of the metabolites, racemic-diastereomeric mixtures, optical isomers, and prodrugs; to pharmaceutical compositions thereof; and to methods of using the metabolites and the compositions in the treatment of diseases associated with reduced levels of growth hormone.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 11, 2003
    Assignee: Pfizer Inc.
    Inventors: S. Cyrus Khojasteh, John P. O'Donnell
  • Publication number: 20020002138
    Abstract: The invention provides metabolites of the compound 2-amino-N[2-(3a(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo-[4,3-c]pyridin-5-yl)-1-(R)-benzyl-oxymethyl-2-oxo-ethyl]-isobutyramide, the racemic-diastereomeric mixtures and optical isomers thereof, the prodrugs thereof, and the pharmaceutically acceptable salts of the metabolites, racemic-diastereomeric mixtures, optical isomers, and prodrugs; to pharmaceutical compositions thereof; and to methods of using the metabolites and the compositions in the treatment of diseases associated with reduced levels of growth hormone.
    Type: Application
    Filed: March 8, 2001
    Publication date: January 3, 2002
    Inventors: S. Cyrus Khojasteh, John P. O'Donnell
  • Patent number: 5131016
    Abstract: Data communication nodes in a network comprising a plurality of nodes linked together to form communication paths negotiate by passing messages to identify to one another the maximum supportable degree of data compression capability. Logical comparisons are made at each node between indications received from upstream and downstream nodes, if any, regarding their own or their received indications of data compression capability with the present node's own degree of compression capability. This enables logical decisions to be made to suport the maximum degree of compression capability over each link or portion of a link between terminal nodes which define the ends of the overall link, thus improving data transmission by providing the highest degree of supportable compression over the longest path length.
    Type: Grant
    Filed: January 9, 1991
    Date of Patent: July 14, 1992
    Assignee: International Business Machines Corporation
    Inventors: John C. Broughton, Robert S. Cahn, James P. Gray, John P. O'Donnell
  • Patent number: 4604481
    Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.
    Type: Grant
    Filed: May 25, 1983
    Date of Patent: August 5, 1986
    Assignee: American Hospital Supply Corporation
    Inventors: Sheung-tsam Kam, Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
  • Patent number: 4593119
    Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R.sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting .beta.-adrenergic blocking activity are also disclosed.
    Type: Grant
    Filed: December 16, 1982
    Date of Patent: June 3, 1986
    Assignee: American Hospital Supply Corporation
    Inventors: Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
  • Patent number: 4405642
    Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.
    Type: Grant
    Filed: November 28, 1980
    Date of Patent: September 20, 1983
    Assignee: American Hospital Supply Corporation
    Inventors: Sheung-tsam Kam, Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
  • Patent number: 4387103
    Abstract: A method for the treatment of prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R.sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting .beta.-adrenergic blocking activity are also disclosed.
    Type: Grant
    Filed: November 28, 1980
    Date of Patent: June 7, 1983
    Assignee: American Hospital Supply Corporation
    Inventors: Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
  • Patent number: 4357341
    Abstract: Specific method of irreversible antagonism of histamine receptors, especially H.sub.1 receptors, in, for example, isolated guinea pig vas deferens by 4(5)-[2-(4-azido-2-nitroanilino)ethyl]imidazole (AAH), which is a photoaffinity analog of histamine actuated unusually by light in the visible spectrum. Additionally, compounds of the present invention are represented by the formula ##STR1## wherein R.sub.1 and R.sub.2 represent an electron withdrawing group of the formula, H, --NO.sub.2, --Cl, --F, --Br, --I, --SO.sub.3 H. When two groups occur, it is not necessary that those groups be identical. In preferred compounds R.sub.1 is --NO.sub.2 and R.sub.2 is H and R.sub.1 is ortho to amine group.R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent a proton or lower alkyl of straight and branched carbon chains. In preferred compounds R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are protons or methyl groups with not more than two of the four positions substituted with an alkyl group. Preference is given for R.sub.4 and R.sub.5.
    Type: Grant
    Filed: May 22, 1981
    Date of Patent: November 2, 1982
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey S. Fedan, John P. O'Donnell, G. Kurt Hogaboom
  • Patent number: 4150320
    Abstract: An integral lens cathode ray tube system includes a cathode ray tube having an electron gun for providing a visual display on a substantially spherical-shaped viewing portion and a glass panel affixed to the viewing portion by a resin disposed therebetween and optically matched to the glass panel and viewing portion of the cathode ray tube.
    Type: Grant
    Filed: July 18, 1977
    Date of Patent: April 17, 1979
    Assignee: GTE Sylvania Incorporated
    Inventors: Robert B. Mitchell, John P. O'Donnell, Harry R. Swank