Patents by Inventor John P. O'Donnell
John P. O'Donnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120249588Abstract: Datacenter datasets and other information are visually displayed in an augmented reality view using a portable device. The visual display of this information is presented along with a visual display of the actual datacenter environment. The combination of these two displays allows installers and technicians to view instructions or other data that are visually correlated to the environment in which they are working.Type: ApplicationFiled: March 21, 2012Publication date: October 4, 2012Applicant: PANDUIT CORP.Inventors: Jack D. Tison, Zachary J. Smolinski, John P. O'Donnell, Brendan F. Doorhy
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Publication number: 20110065783Abstract: Hydroxylated nebivolol metabolites increase NO release from human endothelial cell preparations in a concentration dependent fashion following acute administration. In addition, hydroxylated nebivolol metabolites, including but not limited to 4-hydroxy-6,6?difluoro-, 4-hydroxy-5-phenol-6,6?difluoro-, and 4-hydroxy-8-pheno-6,6?difluoro-, have the ability to increase the capacity for NO release in human endothelial cells following chronic administration. This invention provides hydroxylated nebivolol metabolites and compositions comprising nebivolol and/or at least one hydroxylated metabolite of nebivolol and/or at least one additional compound used to treat cardiovascular diseases or a pharmaceutically acceptable salt thereof.Type: ApplicationFiled: October 20, 2010Publication date: March 17, 2011Inventors: John P. O'Donnell, Walter Owens, Joseph Duncan, Andrew Shaw, Jinn Wu
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Patent number: 7838552Abstract: Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.Type: GrantFiled: November 15, 2005Date of Patent: November 23, 2010Assignee: Forest Laboratories Holdings LimitedInventors: Eric Davis, John P. O'Donnell, Peter Bruce Bottini, Andrew Shaw, R. Preston Mason
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Patent number: 7795243Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.Type: GrantFiled: June 28, 2007Date of Patent: September 14, 2010Assignee: Pfizer, Inc.Inventors: Katherine E. Brighty, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
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Patent number: 7795244Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.Type: GrantFiled: June 30, 2008Date of Patent: September 14, 2010Assignee: Pfizer Inc.Inventors: Katherine Elizabeth Brighty, Anthony Marfat, Dale M. McLeod, John P. O'Donnell
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Publication number: 20090042853Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof preparation thereof formulation thereof and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.Type: ApplicationFiled: June 30, 2008Publication date: February 12, 2009Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. Mcleod, John P. O'Donnell
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Publication number: 20080161296Abstract: Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.Type: ApplicationFiled: November 15, 2005Publication date: July 3, 2008Inventors: Eric Davis, John P. O'Donnell, Peter Bruce Bottini, Andrew Shaw, R. Preston Mason
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Publication number: 20080125408Abstract: The invention relates to prodrugs of sulopenem of formula (I): wherein R1 is —(C2-C8)alkyl, or a solvate or hydrate thereof. The invention also relates to the preparation, formulation, and use of the prodrugs of sulopenem to treat a disorder such as an infection in a patient in need thereof.Type: ApplicationFiled: November 13, 2007Publication date: May 29, 2008Inventors: Katherine Elizabeth Brighty, Anthony Marfat, Dale Gordon McLeod, John P. O'Donnell, Stephen R. Anderson
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Publication number: 20080009474Abstract: Orally bioavailable prodrugs of sulopenem, e.g., and solvates and hydrates thereof, preparation thereof, formulation thereof, and use to treat and prevent infection in mammals such as humans. This abstract is not limiting to the invention.Type: ApplicationFiled: June 28, 2007Publication date: January 10, 2008Inventors: Katherine E. BRIGHTY, Anthony Marfat, Dale G. McLeod, John P. O'Donnell
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Patent number: 6531449Abstract: The invention provides metabolites of the compound 2-amino-N-[2-(3a(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo-[4,3-c]pyridin-5-yl)-1-(R)-benzyl-oxymethyl-2-oxo-ethyl]-isobutyramide, the racemic-diastereomeric mixtures and optical isomers thereof, the prodrugs thereof, and the pharmaceutically acceptable salts of the metabolites, racemic-diastereomeric mixtures, optical isomers, and prodrugs; to pharmaceutical compositions thereof; and to methods of using the metabolites and the compositions in the treatment of diseases associated with reduced levels of growth hormone.Type: GrantFiled: March 8, 2001Date of Patent: March 11, 2003Assignee: Pfizer Inc.Inventors: S. Cyrus Khojasteh, John P. O'Donnell
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Publication number: 20020002138Abstract: The invention provides metabolites of the compound 2-amino-N[2-(3a(R)-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo-[4,3-c]pyridin-5-yl)-1-(R)-benzyl-oxymethyl-2-oxo-ethyl]-isobutyramide, the racemic-diastereomeric mixtures and optical isomers thereof, the prodrugs thereof, and the pharmaceutically acceptable salts of the metabolites, racemic-diastereomeric mixtures, optical isomers, and prodrugs; to pharmaceutical compositions thereof; and to methods of using the metabolites and the compositions in the treatment of diseases associated with reduced levels of growth hormone.Type: ApplicationFiled: March 8, 2001Publication date: January 3, 2002Inventors: S. Cyrus Khojasteh, John P. O'Donnell
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Patent number: 5131016Abstract: Data communication nodes in a network comprising a plurality of nodes linked together to form communication paths negotiate by passing messages to identify to one another the maximum supportable degree of data compression capability. Logical comparisons are made at each node between indications received from upstream and downstream nodes, if any, regarding their own or their received indications of data compression capability with the present node's own degree of compression capability. This enables logical decisions to be made to suport the maximum degree of compression capability over each link or portion of a link between terminal nodes which define the ends of the overall link, thus improving data transmission by providing the highest degree of supportable compression over the longest path length.Type: GrantFiled: January 9, 1991Date of Patent: July 14, 1992Assignee: International Business Machines CorporationInventors: John C. Broughton, Robert S. Cahn, James P. Gray, John P. O'Donnell
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Patent number: 4604481Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.Type: GrantFiled: May 25, 1983Date of Patent: August 5, 1986Assignee: American Hospital Supply CorporationInventors: Sheung-tsam Kam, Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
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Patent number: 4593119Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R.sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting .beta.-adrenergic blocking activity are also disclosed.Type: GrantFiled: December 16, 1982Date of Patent: June 3, 1986Assignee: American Hospital Supply CorporationInventors: Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
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Patent number: 4405642Abstract: A method for the treatment or prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein X is an ester-containing group; R may be lower alkyl, aralkyl or an ester-containing group; R.sub.1 may be lower alkyl; and Ar may be substituted or unsubstituted aromatic; or a pharmaceutically acceptable salt thereof. Novel compounds possessing short acting .beta.-adrenergic blocking activity are also disclosed.Type: GrantFiled: November 28, 1980Date of Patent: September 20, 1983Assignee: American Hospital Supply CorporationInventors: Sheung-tsam Kam, Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
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Patent number: 4387103Abstract: A method for the treatment of prophylaxis of cardiac disorders in a mammal, comprising administering to such mammal a short-acting .beta.-blocking compound of the formula: ##STR1## wherein R may be lower alkyl, aryl, or aralkyl; n may be an integer from 0 to about 10; x may be an integer from 1 to 3; Ar may be substituted or unsubstituted aromatic; R.sub.1 may be lower alkyl, or aralkyl; and pharmaceutically accepted salts thereof. Novel compounds possessing short-acting .beta.-adrenergic blocking activity are also disclosed.Type: GrantFiled: November 28, 1980Date of Patent: June 7, 1983Assignee: American Hospital Supply CorporationInventors: Paul W. Erhardt, Robert J. Borgman, John P. O'Donnell
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Patent number: 4357341Abstract: Specific method of irreversible antagonism of histamine receptors, especially H.sub.1 receptors, in, for example, isolated guinea pig vas deferens by 4(5)-[2-(4-azido-2-nitroanilino)ethyl]imidazole (AAH), which is a photoaffinity analog of histamine actuated unusually by light in the visible spectrum. Additionally, compounds of the present invention are represented by the formula ##STR1## wherein R.sub.1 and R.sub.2 represent an electron withdrawing group of the formula, H, --NO.sub.2, --Cl, --F, --Br, --I, --SO.sub.3 H. When two groups occur, it is not necessary that those groups be identical. In preferred compounds R.sub.1 is --NO.sub.2 and R.sub.2 is H and R.sub.1 is ortho to amine group.R.sub.3, R.sub.4, R.sub.5 and R.sub.6 represent a proton or lower alkyl of straight and branched carbon chains. In preferred compounds R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are protons or methyl groups with not more than two of the four positions substituted with an alkyl group. Preference is given for R.sub.4 and R.sub.5.Type: GrantFiled: May 22, 1981Date of Patent: November 2, 1982Assignee: The United States of America as represented by the Department of Health and Human ServicesInventors: Jeffrey S. Fedan, John P. O'Donnell, G. Kurt Hogaboom
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Patent number: 4150320Abstract: An integral lens cathode ray tube system includes a cathode ray tube having an electron gun for providing a visual display on a substantially spherical-shaped viewing portion and a glass panel affixed to the viewing portion by a resin disposed therebetween and optically matched to the glass panel and viewing portion of the cathode ray tube.Type: GrantFiled: July 18, 1977Date of Patent: April 17, 1979Assignee: GTE Sylvania IncorporatedInventors: Robert B. Mitchell, John P. O'Donnell, Harry R. Swank