Abstract: Procedures and means for evaluating effectiveness of bacterial-lethality, following batch-processed containerized food production operations and aseptic-flow food-production operations as containerized in aseptic-containers, in preparing for non-refrigerated marketing are described. The evaluations significantly expedite determining whether thermally-processed containerized food-production is safe for non-refrigerated marketing. The presence or absence of live spore-forming bacteria is determined chemically free of extended storage requirements relying on a mechanical-failure indication of food-spoilage. Also, a biological-indication verification of microbial-biocidal status of the packaged food is made available.

Abstract: Procedures and means for evaluating effectiveness of bacterial-lethality, following batch-processed containerized food production operations and aseptic-flow food-production operations as containerized in aseptic-containers, in preparing for non-refrigerated marketing are described. The evaluations significantly expedite determining whether thermally-processed containerized food-production is safe for non-refrigerated marketing. The presence or absence of live spore-forming bacteria is determined chemically free of extended storage requirements relying on a mechanical-failure indication of food-spoilage. Also, a biological-indication verification of microbial-biocidal status of the packaged food is made available.

Abstract: Multiple-component integral-structure dual-test sterility indicator, method of assembling physical components, selected spores, and chemical constituents in solution, within the indicator and arranged to enable dual-evaluations of bacterial-lethality of a dry-goods load, resulting from exposure to a selected saturated-steam sterilizing cycle. The chemical constituents are formulated to chemically produce reaction-product, which is quantitatively responsive to the combined effect of cycle steam temperature and time of exposure at that temperature, for providing a promptly-available spectroscopic evaluation of bacterial-lethality. Absorption of narrow-band selected visible-light wavelength by reaction-product, if any, of chemical-constituent solution, is used to quantitatively measure that combined-effect exposure.

Abstract: Multiple early-load-release evaluations of sterilizing effectiveness for both “dry” and “wet” sterilizer loads, are made available by selective spectroscopic quantitative measurements of peak absorption of electromagnetic radiation, in selected UV and visible-light wavelength spectra developed for evaluating thermally-responsive change, in a fluid-state indicator material, which is correlated with the sterilizing effect of a selected cycle on bacterial spores of a sterilizer load. Biological evaluation of sterilizing effectiveness is made available with the same test devices, free of the risk of contamination, by measuring peak absorption of electromagentic radiation at developed wavelength spectra which evaluate pH change, if any, due to spore-growth, or the absence thereof, following a predetermined spore incubation period subsequent to completion of the thermal sterilizing cycle.

Abstract: Thermal sterilization indicator process, apparatus and test indicator product which enable indication of microbial sterility achieved during a thermal sterilizer cycle by measuring visible light absorption due to chemical change in an encapsulated liquid indicator material, including measurements taken when a thermal sterilizer cycle is completed without a time delay requirement for spore growth, and in which the liquid indicator material includes a growth nutrient and microbes, so as to enable verification of achieved microbial sterility by measurement of the liquid indication subsequent to an incubation period following completion of the thermal sterilizer cycle.

Abstract: A method and apparatus for sterilizing highly infectious material. The sterilizer incorporate an inner chamber having no drain line and having a reservoir created by low dams at the bottom of the inner chamber at each end for collecting condensate during the sterilizing cycle. The chamber has a steam jacket. Water for sterilizing can be introduced into the chamber at the time the chamber is loaded.

Abstract: Conditioning of goods for subsequent sterilization with a biocidal agent in a sealable chamber includes removal of air, and moistening and heating the goods to the desired temperature levels. Controlled evacuation of the chamber and coordinated admission of conditioning vapor into the chamber provides cyclic variations in chamber pressure between preselected subatmospheric pressures to subject goods in the chamber to a plurality of cyclic subatmospheric pressure pulses. The time required for the cyclic pressure variations is responsive to load characteristics, including heat and moisture absorption characteristics of the goods being conditioned, and is independent of prescribed times or direct measurement of load temperature. The subatmospheric pressure levels are selected based on the temperature-pressure relationship of the conditioning vapor so that chamber temperature during cyclic pulsing does not exceed the desired sterilization temperature.

Abstract: Conditioning of goods for subsequent sterilization with a biocidal agent in a sealable chamber includes removal of air, and moistening and heating the goods to the desired temperature levels. Controlled evacuation of the chamber and coordinated admission of conditioning vapor into the chamber provides cyclic variations in chamber pressure between preselected subatmospheric pressures to subject goods in the chamber to a plurality of cyclic subatmospheric pressure pulses. The time required for the cyclic pressure variations is responsive to load characteristics, including heat and moisture absorption characteristics of the goods being conditioned, and is independent of prescribed times or direct measurement of load temperature. The subatmospheric pressure levels are selected based on the temperature-pressure relationship of the conditioning vapor so that chamber temperature during cyclic pulsing does not exceed the desired sterilization temperature.

Abstract: A method and apparatus for sterilizing highly infectious material. The sterilizer incorporates an inner chamber having no drain line and having a reservoir created by low dams at the bottom of the inner chamber at each end for collecting condensate during the sterilizing cycle. The chamber has a steam jacket. Water for sterilizing can be introduced into the chamber at the time the chamber is loaded.