Patents by Inventor John R. Mabus

John R. Mabus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azetidinyl diamides as monoacylglycerol lipase inhibitors
    Patent number: 8697683
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: April 15, 2014
    Assignee: Janssen Pharmaceutica NV
    Inventors: Haiyan Bian, Kristen M. Chevalier, Jose Clemente, Peter J. Connolly, Christopher M. Flores, Shu-Chen Lin, Li Liu, John R. Mabus, Mark J. Macielag, Mark E. McDonnell, Philip M. Pitis, Yue-Mei Zhang, Sui-Po Zhang, Bin Zhu
  • PROKINETICIN 1 RECEPTOR
    Publication number: 20120245077
    Abstract: The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
    Type: Application
    Filed: March 26, 2012
    Publication date: September 27, 2012
    Inventors: John R. Mabus, Jeffrey M. Palmer, Stephen M. Prouty, Pamela J. Hornby, Paul R. Wade
  • Methods of treating inflammation using prokineticin 1 receptor antagonists
    Patent number: 8188081
    Abstract: The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: May 29, 2012
    Assignee: Janssen Pharmaceutica, NV
    Inventors: John R. Mabus, Jeffrey M. Palmer, Stephen M. Prouty, Pamela J. Hornby, Paul R. Wade
  • PROKINETICIN 1 RECEPTOR
    Publication number: 20110136811
    Abstract: The present invention relates to methods of monitoring the biological activity of the PK1 receptor.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 9, 2011
    Inventors: John R. Mabus, Jeffrey M. Palmer, Stephen M. Prouty, Pamela J. Hornby, Paul R. Wade
  • Methods of modulating intestine epithelial functions
    Patent number: 7825117
    Abstract: The present invention relates to prokineticin 1 receptor antagonists and methods of using the same to modulate intestine epithelial functions and to treat inflammation in the intestine in a mammal.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: November 2, 2010
    Inventors: John R. Mabus, Jeffrey M. Palmer, Stephen M. Prouty, Pamela J. Hornby, Paul R. Wade