Abstract: An injector having a two stage injection comprising: an outer housing having a first end and a second end; and a plunger assembly for being received within the outer housing and comprising a barrel having a needle disposed at an end thereof and a plunger for dispensing a fluid through the needle; in use the plunger assembly being moveable within the outer housing between a retracted position wherein the needle is at least partially housed within the outer housing and an engaged position wherein the needle projects outwardly of a needle opening located at the first end of the outer housing and whereby a rotary inhibiting mechanism interacts with the plunger assembly to inhibit movement of the plunger within the barrel until the plunger assembly has reached the engaged position.

Abstract: A single layer roofing material having a headlap portion and a tab portion wherein the headlap portion has a color-value gradient or gradation and the tab portion has tabs and openings. The tabs may have a relatively uniform color. Openings between tabs expose the color gradient of the headlap portion when a first sheet of the roofing material is installed over a second sheet on a structure. A plurality of horizontal striations may be used to establish the desired color-value gradient. An illusion of depth or thickness is created when the roofing material is applied to a structure, such as a roof deck. The amount of tone and contrast may be selected to create the desired illusion of depth or thickness. The amount of contrast may be varied depending upon the color selected for each roofing material. The number of horizontal striations and their width may also be varied to provide the desired color-value gradient. Tab color, shape and size may also be varied to enhance the illusion of depth.

Abstract: The present invention relates to a method for enhancing immune function, which comprises administering orally to a subject in need thereof effective amounts of glutathione or a salt thereof. The present invention also relates to an oral agent comprising glutathione or a salt thereof for enhancing immune function, and glutathione or a salt thereof for use in enhancing immune function.

Abstract: A roofing system comprising laminated roofing shingles having a reduced-width headlap portion and a buttlap portion, wherein the roofing system comprises a plurality of courses, and wherein a trailing edge of a subsequently installed shingle in a course overlaps the leading edge of an adjacent previously installed shingle in the same course. The reduced-width headlap portion of the roofing shingles has a width that is less than the width of the buttlap portion. The roofing shingle comprises a first and a second shingle sheet and the lateral edges of the first shingle sheet are aligned with the lateral edges of the second sheet.

Abstract: A roofing system comprising laminated roofing shingles having a reduced-width headlap portion and a buttlap portion, wherein the roofing system comprises a plurality of courses, and wherein a trailing edge of a subsequently installed shingle in a course overlaps the leading edge of an adjacent previously installed shingle in the same course. The reduced-width headlap portion of the roofing shingles has a width that is less than the width of the buttlap portion. The roofing shingle comprises a first and a second shingle sheet and the lateral edges of the first shingle sheet are aligned with the lateral edges of the second sheet.