Patents by Inventor John S. Hatcher

John S. Hatcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of EGFR and/or HER2 and methods of use
    Patent number: 11945816
    Abstract: The application relates to a compound having Formula X: which modulates the activity of HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, plays a role.
    Type: Grant
    Filed: October 20, 2021
    Date of Patent: April 2, 2024
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: John M. Hatcher, Nathanael S. Gray, Jaebong Jang, Dries De Clercq, Pasi Janne, Jamie A. Saxon, Michael Eck, David A. Scott, Alyssa Verano
  • SYSTEM AND METHOD FOR TRANSFERRING HEAT USING AN EXPANDED GAS
    Publication number: 20140209276
    Abstract: A system includes a fuel source for providing a fuel, a first expansion valve formed in a first fuel line connected to the fuel source, for expanding the fuel, and a heat transfer device for delivering a heat transfer medium to the first expansion valve such that the heat transfer medium is cooled by contacting the first expansion valve. Another system includes a fuel source for providing a fuel, a first expansion valve formed in a first fuel line connected to the fuel source, for expanding the fuel, a heat exchanger connected via the first fuel line to the expansion valve, the heat exchanger being cooled by the expanded fuel, and a fan for blowing air over the heat exchanger such that the air is cooled by contacting the heat exchanger. Another system includes pneumatic or hydraulic operated system devices.
    Type: Application
    Filed: January 29, 2014
    Publication date: July 31, 2014
    Applicant: NEXOVATION, Inc.
    Inventors: Robert J. Sexton, John S. Hatcher