Patents by Inventor John Schmieg

John Schmieg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
    Patent number: 7771726
    Abstract: The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes a synthetic glycolipid compound of Formula I, as described herein. According to the present invention, the use of a compound of Formula I as an adjuvant is attributed at least in part to the enhancement and/or extension of antigen-specific Th1-type responses, in particular, CD8+ T cell responses. The methods and compositions of the present invention can be useful for prophylaxis and treatment of various infectious and neoplastic diseases.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: August 10, 2010
    Assignees: New York University, The Research Foundation of the City University of New York, Aaron Diamond Aids Research Center
    Inventors: Moriya Tsuji, John Schmieg, Richard Franck, Yaoxing Huang
  • Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
    Publication number: 20050192248
    Abstract: The present invention relates to methods and compositions for augmenting an immunogenicity of an antigen in a mammal, comprising administering said antigen together with an adjuvant composition that includes a synthetic glycolipid compound of Formula I, as described herein. According to the present invention, the use of a compound of Formula I as an adjuvant is attributed at least in part to the enhancement and/or extension of antigen-specific Th1-type responses, in particular, CD8+ T cell responses. The methods and compositions of the present invention can be useful for prophylaxis and treatment of various infectious and neoplastic diseases.
    Type: Application
    Filed: October 8, 2004
    Publication date: September 1, 2005
    Applicant: NYU Medical Center
    Inventors: Moriya Tsuji, John Schmieg, Richard Franck, Yaoxing Huang