Abstract: The notched base ring comprises a base ring sheet body including a top portion, a bottom portion, a first end connecting the top portion to the bottom portion, and a second end connecting the bottom portion to the top portion. The top portion includes a plurality of attachment lugs and defines a plurality of notches, each notch being at least partially defined by two lugs disposed on opposite sides of the notch, the top portion also including an angled top edge that is disposed at each of the attachment lugs, and the bottom portion includes a bottom support edge.

Abstract: The notched base ring comprises a base ring sheet body including a top portion, a bottom portion, a first end connecting the top portion to the bottom portion, and a second end connecting the bottom portion to the top portion. The top portion includes a plurality of attachment lugs and defines a plurality of notches, each notch being at least partially defined by two lugs disposed on opposite sides of the notch, the top portion also including an angled top edge that is disposed at each of the attachment lugs, and the bottom portion includes a bottom support edge.

Abstract: A pressure washer system comprises a cleaning fluid tank defining a cleaning fluid supply outlet, and a pump, engine and generator (PEG) unit including a pump defining a cleaning fluid pump inlet disposed vertically below the cleaning fluid supply outlet of the cleaning fluid supply tank.

Abstract: A modular design for a pressure washer system comprises a support frame including a top mounting surface, a first power assembly configured to be mounted to the support frame, and a cage assembly including a cage frame and a cage attached to the cage frame and configured to extend upwardly from the cage frame at least partially surrounding the power assembly, wherein the cage frame is configured to be attached to the support frame.

Abstract: A pressure washer system comprises a cleaning fluid tank defining a cleaning fluid supply outlet, and a pump, engine and generator (PEG) unit including a pump defining a cleaning fluid pump inlet disposed vertically below the cleaning fluid supply outlet of the cleaning fluid supply tank.

Abstract: A modular design for a pressure washer system comprises a support frame including a top mounting surface, a first power assembly configured to be mounted to the support frame, and a cage assembly including a cage frame and a cage attached to the cage frame and configured to extend upwardly from the cage frame at least partially surrounding the power assembly, wherein the cage frame is configured to be attached to the support frame.

Abstract: A method of use for a low cleaning fluid shutdown system according to an embodiment of the present disclosure is provided. The method comprising attaching an angled plumbing fitting to a bottom wall of a cleaning fluid supply tank, inserting a float switch into an switch mount fitting, and attaching the switch mount fitting to the angled plumbing fitting.

Abstract: The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells.

Abstract: The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells.

Abstract: The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells.

Abstract: The present invention includes methods of performing ex vivo expansion of gene-modified hematopoietic stem cells which are useful for many applications involving bone marrow transplantation and ex vivo gene therapy. The present invention further includes the gene-modified hematopoietic stem cells that are used and produced by such methods. Such gene-modified hematopoietic stem cells can also contain a second heterologous gene. In addition, the present invention also includes methods of engrafting the gene-modified hematopoietic stem cells of the present invention into animals, including for ex vivo gene therapy and for reconstitution of hematopoietic cells in ablated mammals. The present invention also provides a method of isolating stem cells.

Abstract: The present invention relates to multi-drug resistance, specifically to multi-drug resistant protein 4 (MRP4) and uses thereof. The present invention provides nucleic acid encoding MRP4, MRP4 protein, antibody reactive to MRP4 and discloses MRP4 as perhaps the first mammalian efflux pump described for nucleoside analogs. The present invention provides the first example of a role of MRP4 in drug resistance. Certain patients who develop drug resistance to anti-microbial therapy or anti-cancer therapy may develop cellular resistance mediated by MRP4. Accordingly, the present invention possesses both diagnostic and therapeutic utility as diagnostic kits, including drug assays and screens are contemplated, as well as pharmaceutical compositions and the corresponding methods of their respective use. For example, a diagnostic kit is disclosed that may be used in order to facilitate determination of patient susceptibility to MRP4 mediated drug resistance.

Abstract: The present invention includes methods of identifying and/or isolating stem cells based on expression of BCRP. The present invention also describes methods of obtaining and/or using cell populations enriched for stem cells. In addition, methods are provided for diagnosing and/or prognosing leukemia, particularly human acute myelogenous leukemia (AML), through assaying for BCRP expression in leukemic cells.