Patents by Inventor John Scott T. Jaques

John Scott T. Jaques has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant canine thyroid stimulating hormone and methods of production and use thereof
    Patent number: 7838492
    Abstract: The invention includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 1, which encodes the ? subunit of canine thyroid stimulating hormone (TSH). The invention also includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 2, which encodes the ? subunit of canine TSH. The invention also includes a method of producing a recombinant canine thyroid stimulating hormone (rcTSH) subunit by expressing a nucleic acid having a sequence of SEQ ID NO: 1 and a nucleic acid having a sequence of SEQ ID NO: 2 in a transgenic insect cell modified to sialylate proteins and producing a sialylated rcTSH subunit. The insect cell may be a lepidopteran cell. The rcTSH may be used for diagnosis and treatment. It may be used to diagnose canine hypothyroidism.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: November 23, 2010
    Inventors: John Scott T. Jaques, Donald L. Jarvis
  • RECOMBINANT CANINE THYROID STIMULATING HORMONE AND METHODS OF PRODUCTION AND USE THEREOF
    Publication number: 20100196276
    Abstract: The invention includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 1, which encodes the ? subunit of canine thyroid stimulating hormone (TSH). The invention also includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 2, which encodes the ? subunit of canine TSH. The invention also includes a method of producing a recombinant canine thyroid stimulating hormone (rcTSH) subunit by expressing a nucleic acid having a sequence of SEQ ID NO: 1 and a nucleic acid having a sequence of SEQ ID NO: 2 in a transgenic insect cell modified to sialylate proteins and producing a sialylated rcTSH subunit. The insect cell may be a lepidopteran cell. The rcTSH may be used for diagnosis and treatment. It may be used to diagnose canine hypothyroidism.
    Type: Application
    Filed: January 9, 2009
    Publication date: August 5, 2010
    Inventors: John Scott T. Jaques, Donald L. Jarvis
  • Recombinant canine thyroid stimulating hormone and methods of production and use thereof
    Patent number: 7479549
    Abstract: The invention includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 1, which encodes the ? subunit of canine thyroid stimulating hormone (TSH). The invention also includes a nucleic acid having a sequence at least 98% homologous to SEQ ID NO: 2, which encodes the ? subunit of canine TSH. The invention also includes a method of producing an recombinant canine thyroid stimulating hormone (rcTSH) subunit by expressing a nucleic acid having a sequence of SEQ ID NO: 1 and a nucleic acid having a sequence of SEQ ID NO: 2 in a transgenic insect cell modified to sialylate proteins and producing a sialylated rcTSH subunit. The insect cell may be a lepidopteran cell. The rcTSH may be used for diagnosis and treatment. It may be used to diagnose canine hypothyroidism.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: January 20, 2009
    Inventors: John Scott T. Jaques, Donald L. Jarvis