Abstract: This invention generally relates to the field of somatic gene therapy. The invention provides a nucleic acid construct comprising a transgene encoding a therapeutic protein, a tetracycline-responsive aptazyme sequence, and inverted terminal repeats (ITRs). The nucleic acid construct can be transferred to a subject in need thereof in the form of a viral vector, in particular an adeno-associated virus (AAV) vector. The Tet-responsive aptazyme sequence allows for a tightly controlled expression of the transgene in the subject, thereby avoiding toxic side effects. The nucleic acid construct and the viral vectors comprising same are particularly useful in the treatment of proliferative diseases like cancer.

Abstract: A liquid dispensing faucet including a flow control lever engaging a sealing member within an internal cavity of a faucet body. The sealing member is held within the faucet body in an oversized recess permitting liquid to flow about all sides of the sealing member when the flow control handle is placed in an open position and liquid flows through the faucet body. The faucet body may have a removable spout mounted at a second end of the body. An air inlet may be included within a flow path of the liquid downstream of the sealing member. This air inlet promotes the removal of residual liquid from the flow path when the flow lever is in a closed position and is positioned to discourage flow of the liquid through the air inlet when the flow lever is in an open position.

Abstract: A sanitary faucet with a foam control feature adaptable for dispensing pressurized fluids. The sanitary faucet includes a valve body, a plunger assembly, a flow restrictor assembly and an adjusting screw assembly. Also disclosed is a method of variably regulating fluid flow pressure and the production of foam in the sanitary faucet.

Abstract: A device and method for locating the point on a wall at which a nail, or other wire suspending element, is to be installed for the hanging of pictures and the like. The device includes a retrieval arm operable for engaging the framing wire of a picture and a wall striking element operable for marking on a wall the place for a nail or other hardware to be secured. The device also includes a flanged assembly operable for receiving the retrieval arm and selectively engaging and disengaging the retrieval arm. The flanged assembly is disposed for promotional information or attachments.