Patents by Inventor John T. McCaffrey

John T. McCaffrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9447696
    Abstract: A blade outer air seal system for a gas turbine engine includes a plurality of ring carriers made of a first material having a first coefficient of thermal expansion. A plurality of seal segments are carried, respectively, on the plurality of ring carriers. A ring member is carried in the plurality of ring carriers. The ring member is made of a second material that is different from the first material in composition. The second material has a second coefficient of thermal expansion such that the first coefficient of thermal expansion is 75-175% of the second coefficient of thermal expansion.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: September 20, 2016
    Assignee: United Technologies Corporation
    Inventors: Michael G. McCaffrey, Brandon T. Rouse, Thomas Almy, Igor S. Garcia, John R. Farris, Mark Borja
  • Patent number: 8075752
    Abstract: The invention relates to an electrochemical sensor and method for providing the sensor having an insulator, an electrode deposited on the insulator, an electrolytic material in contact with the electrode for providing an electrical connection, and a cooling and heating element in contact with the insulator and spaced apart from the electrode for adjusting a temperature of the sensor.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: December 13, 2011
    Assignee: PerkinElmer Health Sciences, Inc.
    Inventors: Avinash Dalmia, Mario Carozza, Michael J. Rafa, Donald L. Groeschner, John T. McCaffrey
  • Patent number: 7485262
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface to re-absorb the moisture from the surface.
    Type: Grant
    Filed: December 19, 2002
    Date of Patent: February 3, 2009
    Assignee: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Patent number: 7060223
    Abstract: Disclosed herein is a polymeric sampling swab for obtaining samples of an analyte of interest from solid surfaces or from liquid substances. The polymeric material of which the swab is composed is characterized by a high resistance to chemical and mechanical degradation. The sampling swab of the present invention is further characterized by a high internal void volume and a high absorptive capacity for fluids. The swab of the present invention is particularly suited for obtaining samples for use in chemiluminescent assays for, among other analytes of interest, microbial contamination. Also disclosed is a polymeric disc for loading with reagent mixtures suitable for use in bioluminescent assay procedures. The reagent disc of the invention is characterized by high resistance to chemical and mechanical degradation. In addition, the disc has a high void volume and high absorptive capacity.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: June 13, 2006
    Assignee: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey
  • Patent number: 6927851
    Abstract: A hand-held assay device measuring chemiluminescence generated by as ample of ATP or other entity capable of chemically reacting to generate photoluminescence includes a photodiode detecting light which is emitted from the sample to produce a sample signal, another photodiode generating a reference signal in response to environmental changes, switched integrators amplifying the sensor signal over a controllable integration time to detect an output signal indicative of the presence of the sample.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: August 9, 2005
    Assignee: Neogen Corporation
    Inventors: John T. McCaffrey, Szilveszter Jando, Sunita Carrasko
  • Patent number: 6887681
    Abstract: Disclosed is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: May 3, 2005
    Assignee: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Patent number: 6881554
    Abstract: Disclosed is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: April 19, 2005
    Assignee: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Publication number: 20030186458
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface-to re-absorb the moisture from the surface.
    Type: Application
    Filed: January 17, 2003
    Publication date: October 2, 2003
    Applicant: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Publication number: 20030129765
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface-to re-absorb the moisture from the surface.
    Type: Application
    Filed: January 17, 2003
    Publication date: July 10, 2003
    Applicant: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Publication number: 20030109057
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface to re-absorb the moisture from the surface.
    Type: Application
    Filed: December 19, 2002
    Publication date: June 12, 2003
    Applicant: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Patent number: 6548018
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface to re-absorb the moisture from the surface.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: April 15, 2003
    Assignee: Neogen Corporation
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Publication number: 20020187076
    Abstract: Disclosed herein is a polymeric sampling swab for obtaining samples of an analyte of interest from solid surfaces or from liquid substances. The polymeric material of which the swab is composed is characterized by a high resistance to chemical and mechanical degradation. The sampling swab of the present invention is further characterized by a high internal void volume and a high absorptive capacity for fluids. The swab of the present invention is particularly suited for obtaining samples for use in chemiluminescent assays for, among other analytes of interest, microbial contamination. Also disclosed is a polymeric disc for loading with reagent mixtures suitable for use in bioluminescent assay procedures. The reagent disc of the invention is characterized by high resistance to chemical and mechanical degradation. In addition, the disc has a high void volume and high absorptive capacity.
    Type: Application
    Filed: March 29, 2001
    Publication date: December 12, 2002
    Inventors: Joseph L. DiCesare, John T. McCaffrey
  • Publication number: 20020001539
    Abstract: Disclosed herein is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained personnel under the relatively harsh and variable conditions found in the field, for example in fast food restaurants and other food preparation areas. The chemiluminescence reaction that is the source of the analytical signal in the disclosed assay device and method is preferably based on a luciferase/luciferin system. The method for sampling disclosed herein comprises the steps of pre-wetting the sampling swab to a level below that of absorptive saturation; wiping a surface to be sampled with the swab with sufficient pressure to expel the wetting solution onto the surface; and, after reducing the pressure exerted on the sampling swab, further wiping the surface to re-absorb the moisture from the surface.
    Type: Application
    Filed: March 29, 2001
    Publication date: January 3, 2002
    Inventors: Joseph L. DiCesare, John T. McCaffrey, David Clark, Michael I. Crockett
  • Publication number: 20010038450
    Abstract: A hand-held assay device measuring chemiluminescence generated by as ample of ATP or other entity capable of chemically reacting to generate photoluminescence includes a photodiode detecting light which is emitted from the sample to produce a sample signal, another photodiode generating a reference signal in response to environmental changes, switched integrators amplifying the sensor signal over a controllable integration time to detect an output signal indicative of the presence of the sample.
    Type: Application
    Filed: March 29, 2001
    Publication date: November 8, 2001
    Inventors: John T. McCaffrey, Szilveszter Jando, Sunita Carrasko
  • Patent number: 4726679
    Abstract: The optical measurement signals in a flame atomic absorption spectrophotometer are first amplified in a substantially linear variable gain amplifier. The gain of the variable gain amplifier is adjusted to provide a predetermined magnitude of output signal during a calibration phase of the spectrophotometer. The resultant output signals from the variable gain amplifier are then converted to a logarithmic function in a logarithmic amplifier during optical absorption measurements.
    Type: Grant
    Filed: March 3, 1986
    Date of Patent: February 23, 1988
    Assignee: The Perkin-Elmer Corporation
    Inventor: John T. McCaffrey
  • Patent number: 4716342
    Abstract: The circuit includes an inverter to be connected to a source of d.c. power. The inverter has a transformer with a center-tapped primary winding. Separate controllable switching devices are connected to the respective ends of the primary winding. Both switching devices are arranged to be connected in common to one output terminal of the d.c. power source. The center tap of the transformer primary winding is arranged for connection to the other output terminal of the d.c. power source. The transformer has a laminated silicon steel core, and includes a secondary winding arranged for connection across the input terminals of a gaseous discharge lamp. A control circuit is connected to control conduction by the separate controllable switching devices in alternating sequence at a desired frequency of operation.
    Type: Grant
    Filed: December 5, 1985
    Date of Patent: December 29, 1987
    Assignee: The Perkin-Elmer Corporation
    Inventor: John T. McCaffrey
  • Patent number: 4647201
    Abstract: The interlock assures that the end of a drain trap entrance pipe is covered with liquid. The system includes a control circuit with a circuit element which changes impedance with temperature changes. The circuit element is arranged to be thermally coupled with the drain trap liquid when the discharge end of the drain trap entrance pipe is immersed in the liquid. The circuit applies a current to the circuit element to thereby apply energy thereto. The circuit element achieves a lower steady-state temperature when thermally coupled with the liquid. The control circuit is operable to detect the difference in resistance when the circuit element is at the lower temperature. The control circuit is connected to a valve device for controlling combustion gas for the spectrophotometer and is operable to enable the valve device to enable the spectrophotometer when the circuit element is at the lower temperature and to disable the spectrophotometer at a higher temperature.
    Type: Grant
    Filed: January 13, 1986
    Date of Patent: March 3, 1987
    Assignee: The Perkin-Elmer Corporation
    Inventor: John T. McCaffrey