Patents by Inventor John T. Strony

John T. Strony has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • "The Use of a PAR-1 Antagonist in Combination with a P2Y12 ADP Receptor Antagonist for Inhibition of Thrombosis"
    Publication number: 20120184504
    Abstract: The treatment and prevention of thrombotic events are provided through co-administration of PAR-1 and the P2Y12 ADP receptor antagonists. Combined inhibition of the PAR-1 and the P2Y12 ADP platelet activation pathways had synergistic antithrombotic and antiplatelet effects, as demonstrated in co-administration of SCH 602539 and cangrelor.
    Type: Application
    Filed: September 24, 2010
    Publication date: July 19, 2012
    Inventors: John T. Strony, Madhu Chintala
  • THROMBIN RECEPTOR ANTAGONISTS AS PROPHYLAXIS TO COMPLICATIONS FROM CARDIOPULMONARY SURGERY
    Publication number: 20090062239
    Abstract: Disclosed herein are methods of preventing, inhibiting, or ameliorating complications associated with cardiopulmonary bypass surgery by the use of a thrombin receptor antagonist compound. Among the thrombin receptor antagonist compounds useful in these methods are those of Formulas I and II, described herein.
    Type: Application
    Filed: October 30, 2008
    Publication date: March 5, 2009
    Inventors: Enrico P. Veltri, John T. Strony, Gail Berman
  • REDUCTION OF ADVERSE EVENTS AFTER PERCUTANEOUS INTERVENTION BY USE OF A THROMBIN RECEPTOR ANTAGONIST
    Publication number: 20080234236
    Abstract: Disclosed are methods of preventing adverse clinical events in a patient undergoing a percutaneous coronary intervention procedure or a peripheral percutaneous interventional procedure comprising administering a therapeutically effective amount of a thrombin receptor antagonist, such as SCH 530348, to the patient. Administration of a loading dose of about 40 mg of SCH 530348 in as little as one hour prior to the procedure can result in therapeutically effective levels of platelet aggregation.
    Type: Application
    Filed: March 19, 2008
    Publication date: September 25, 2008
    Inventors: Enrico P. Veltri, John T. Strony, Madhu Chintala
  • Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
    Patent number: 7071181
    Abstract: The present invention provides methods of treating diabetes and associated conditions by administering a composition including at least one sterol or 5?-stanol absorption inhibitor or compositions or therapeutic combinations including: (a) at least one antidiabetic medication; and (b) at least one sterol or 5?-stanol absorption inhibitor.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: July 4, 2006
    Assignee: Schering Corporation
    Inventors: Harry R. Davis, Teddy Kosoglou, Gilles J. Picard, Rudyard J. Ress, John T. Strony, Enrico P. Veltri
  • Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
    Patent number: 7056906
    Abstract: The present invention provides compositions, therapeutic combinations and methods including: (a) at least one hormone replacement therapy composition; and (b) at least one sterol absorption inhibitor which can be useful for treating vascular conditions in post-menopausal women and lowering plasma levels of sterols or 5?-stanols.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: June 6, 2006
    Assignee: Schering Corporation
    Inventor: John T. Strony
  • Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
    Patent number: 7053080
    Abstract: The present invention provides methods for the treatment of obesity using sterol or 5?-stanol absorption inhibitors and compositions and therapeutic combinations including sterol or 5?-stanol absorption inhibitors and at least one obesity control medication.
    Type: Grant
    Filed: September 19, 2002
    Date of Patent: May 30, 2006
    Assignee: Schering Corporation
    Inventors: Harry R. Davis, Rudyard J. Ress, John T. Strony, Enrico P. Veltri
  • Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
    Publication number: 20040214811
    Abstract: The present invention provides methods of treating diabetes and associated conditions by administering a composition including at least one sterol or 5&agr;-stanol absorption inhibitor or compositions or therapeutic combinations including: (a) at least one antidiabetic medication; and (b) at least one sterol or 5&agr;-stanol absorption inhibitor.
    Type: Application
    Filed: September 19, 2002
    Publication date: October 28, 2004
    Applicant: Schering Corporation
    Inventors: Harry R. Davis, Teddy Kosoglou, Gilles J. Picard, Rudyard J. Ress, John T. Strony, Enrico P. Veltri
  • Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
    Publication number: 20030119428
    Abstract: The present invention provides methods for the treatment of obesity using sterol or 5&agr;-stanol absorption inhibitors and compositions and therapeutic combinations including sterol or 5&agr;-stanol absorption inhibitors and at least one obesity control medication.
    Type: Application
    Filed: September 19, 2002
    Publication date: June 26, 2003
    Applicant: Schering Corporation
    Inventors: Harry R. Davis, Rudyard J. Ress, John T. Strony, Enrico P. Veltri
  • Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
    Publication number: 20030119796
    Abstract: The present invention provides compositions, therapeutic combinations and methods including: (a) at least one hormone replacement therapy composition; and (b) at least one sterol absorption inhibitor which can be useful for treating vascular conditions in post-menopausal women and lowering plasma levels of sterols or 5&agr;-stanols.
    Type: Application
    Filed: September 19, 2002
    Publication date: June 26, 2003
    Applicant: Schering Corporation
    Inventor: John T. Strony
  • Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
    Publication number: 20030069221
    Abstract: The present invention provides compositions, therapeutic combinations and methods including: (a) at least one sterol absorption inhibitor and (b) at least one cardiovascular agent different from the sterol absorption inhibitor, which can be useful for treating vascular conditions, obesity, diabetes and lowering plasma levels of sterols.
    Type: Application
    Filed: January 25, 2002
    Publication date: April 10, 2003
    Applicant: Schering Corporation
    Inventors: Teddy Kosoglou, Rudyard J. Ress, John T. Strony, Enrico P. Veltri, William Hauer
  • Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
    Publication number: 20020147184
    Abstract: The present invention provides compositions, therapeutic combinations and methods including: (a) at least one sterol absorption inhibitor; and (b) at least one blood modifier, which can be useful for treating vascular conditions and lowering plasma levels of sterols.
    Type: Application
    Filed: January 25, 2002
    Publication date: October 10, 2002
    Applicant: Schering Corporation
    Inventors: Teddy Kosoglou, Rudyard J. Ress, John T. Strony, Enrico P. Veltri